ICD-10-CM Excludes1 Notes · Chapter 2 · FY 2027 C00-D49

Excludes1 Notes in Chapter 2: Neoplasms ICD-10-CM

An Excludes1 note means "NOT CODED HERE": the excluded code should never be reported together with the code above the note. In Chapter 2 (C00-D49), notes printed in the chapter name other codes 460 times, and Excludes1 Notes anywhere in the Tabular List name the chapter’s codes 516 times, covering 292 distinct codes, categories and ranges. Switch views to read the list either way.

✓ From the official FY 2027 ICD-10-CM Tabular ListDefinitions follow the Official Guidelines, Section I.A
460
References in Its Notes
516
References to Its Codes
292
Chapter Codes Named
C00-D49
Chapter 2
Chapter 2

Excludes1 Notes by the code that carries the note

206 of 206 shown
  • C00 Malignant neoplasm of lip applies to 9 codes
    • malignant melanoma of lip (C43.0)
    • Merkel cell carcinoma of lip (C4A.0)
    • other and unspecified malignant neoplasm of skin of lip (C44.0-)
  • C05 Malignant neoplasm of palate applies to 5 codes
    • Kaposi's sarcoma of palate (C46.2)
  • C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx applies to 3 codes
    • malignant neoplasm of oral cavity NOS (C06.9)
  • C14.8 Malignant neoplasm of overlapping sites of lip, oral cavity and pharynx
    • 'book leaf' neoplasm [ventral surface of tongue and floor of mouth] (C06.89)
  • Block note Block C15-C26 Malignant neoplasms of digestive organs applies to 60 codes
    • Kaposi's sarcoma of gastrointestinal sites (C46.4)
  • C15.5 Malignant neoplasm of lower third of esophagus
    • malignant neoplasm of cardio-esophageal junction (C16.0)
  • C17 Malignant neoplasm of small intestine applies to 6 codes
    • malignant carcinoid tumors of the small intestine (C7A.01)
  • C17.2 Malignant neoplasm of ileum
    • malignant neoplasm of ileocecal valve (C18.0)
  • C17.3 Meckel's diverticulum, malignant
    • Meckel's diverticulum, congenital (Q43.0)
  • C18 Malignant neoplasm of colon applies to 10 codes
    • malignant carcinoid tumors of the colon (C7A.02-)
  • C18.7 Malignant neoplasm of sigmoid colon
    • malignant neoplasm of rectosigmoid junction (C19)
  • C19 Malignant neoplasm of rectosigmoid junction
    • malignant carcinoid tumors of the colon (C7A.02-)
  • C20 Malignant neoplasm of rectum
    • malignant carcinoid tumor of the rectum (C7A.026)
  • C22 Malignant neoplasm of liver and intrahepatic bile ducts applies to 8 codes
    • malignant neoplasm of biliary tract NOS (C24.9)
    • secondary malignant neoplasm of liver and intrahepatic bile duct (C78.7)
  • C22.1 Intrahepatic bile duct carcinoma
    • malignant neoplasm of hepatic duct (C24.0)
  • C24 Malignant neoplasm of other and unspecified parts of biliary tract applies to 4 codes
    • malignant neoplasm of intrahepatic bile duct (C22.1)
  • C26 Malignant neoplasm of other and ill-defined digestive organs applies to 3 codes
    • malignant neoplasm of peritoneum and retroperitoneum (C48.-)
  • C26.1 Malignant neoplasm of spleen
  • C26.9 Malignant neoplasm of ill-defined sites within the digestive system
    • malignant neoplasm of abdominal NOS (C76.2)
    • malignant neoplasm of intra-abdominal NOS (C76.2)
  • Block note Block C30-C39 Malignant neoplasms of respiratory and intrathoracic organs applies to 40 codes
  • C30.0 Malignant neoplasm of nasal cavity
    • malignant neoplasm of nasal bone (C41.0)
    • malignant neoplasm of nose NOS (C76.0)
    • malignant neoplasm of olfactory bulb (C72.2-)
    • malignant neoplasm of posterior margin of nasal septum and choana (C11.3)
    • malignant melanoma of skin of nose (C43.31)
    • malignant neoplasm of turbinates (C41.0)
    • other and unspecified malignant neoplasm of skin of nose (C44.301, C44.311, C44.321, C44.391)
  • C30.1 Malignant neoplasm of middle ear
    • malignant neoplasm of auricular canal (external) (C43.2-,C44.2-)
    • malignant neoplasm of bone of ear (meatus) (C41.0)
    • malignant neoplasm of cartilage of ear (C49.0)
    • malignant melanoma of skin of (external) ear (C43.2-)
    • other and unspecified malignant neoplasm of skin of (external) ear (C44.2-)
  • C34 Malignant neoplasm of bronchus and lung applies to 16 codes
    • Kaposi's sarcoma of lung (C46.5-)
    • malignant carcinoid tumor of the bronchus and lung (C7A.090)
  • C37 Malignant neoplasm of thymus
    • malignant carcinoid tumor of the thymus (C7A.091)
  • C38 Malignant neoplasm of heart, mediastinum and pleura applies to 6 codes
  • C38.0 Malignant neoplasm of heart
    • malignant neoplasm of great vessels (C49.3)
  • C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs applies to 2 codes
    • intrathoracic malignant neoplasm NOS (C76.1)
    • thoracic malignant neoplasm NOS (C76.1)
  • Block note Block C40-C41 Malignant neoplasms of bone and articular cartilage applies to 24 codes
    • malignant neoplasm of bone marrow NOS (C96.9)
    • malignant neoplasm of synovia (C49.-)
  • C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites applies to 6 codes
    • malignant neoplasm of bones of limbs (C40.-)
    • malignant neoplasm of cartilage of ear (C49.0)
    • malignant neoplasm of cartilage of eyelid (C49.0)
    • malignant neoplasm of cartilage of larynx (C32.3)
    • malignant neoplasm of cartilage of limbs (C40.-)
    • malignant neoplasm of cartilage of nose (C30.0)
  • C41.2 Malignant neoplasm of vertebral column
    • malignant neoplasm of sacrum and coccyx (C41.4)
  • C43 Malignant melanoma of skin applies to 24 codes
  • C43.0 Malignant melanoma of lip
    • malignant neoplasm of vermilion border of lip (C00.0-C00.2)
  • C44 Other and unspecified malignant neoplasm of skin applies to 101 codes
    • Kaposi's sarcoma of skin (C46.0)
    • malignant melanoma of skin (C43.-)
    • malignant neoplasm of skin of genital organs (C51-C52, C60.-, C63.2)
    • Merkel cell carcinoma (C4A.-)
  • C44.0 Other and unspecified malignant neoplasm of skin of lip applies to 4 codes
    • malignant neoplasm of lip (C00.-)
  • C44.1 Other and unspecified malignant neoplasm of skin of eyelid, including canthus applies to 25 codes
    • connective tissue of eyelid (C49.0)
  • C44.2 Other and unspecified malignant neoplasm of skin of ear and external auricular canal applies to 12 codes
    • connective tissue of ear (C49.0)
  • C44.5 Other and unspecified malignant neoplasm of skin of trunk applies to 12 codes
  • C45.0 Mesothelioma of pleura
    • other malignant neoplasm of pleura (C38.4)
  • C45.1 Mesothelioma of peritoneum
    • other malignant neoplasm of soft tissue of peritoneum (C48.-)
  • C45.2 Mesothelioma of pericardium
    • other malignant neoplasm of pericardium (C38.0)
  • C47 Malignant neoplasm of peripheral nerves and autonomic nervous system applies to 13 codes
    • Kaposi's sarcoma of soft tissue (C46.1)
  • C47.0 Malignant neoplasm of peripheral nerves of head, face and neck
    • malignant neoplasm of peripheral nerves of orbit (C69.6-)
  • C48 Malignant neoplasm of retroperitoneum and peritoneum applies to 4 codes
    • Kaposi's sarcoma of connective tissue (C46.1)
    • mesothelioma (C45.-)
  • C49 Malignant neoplasm of other connective and soft tissue applies to 20 codes
  • C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck
    • connective tissue of orbit (C69.6-)
  • C49.3 Malignant neoplasm of connective and soft tissue of thorax
    • malignant neoplasm of breast (C50.-)
    • malignant neoplasm of heart (C38.0)
    • malignant neoplasm of mediastinum (C38.1-C38.3)
    • malignant neoplasm of thymus (C37)
  • C4A.0 Merkel cell carcinoma of lip
    • malignant neoplasm of vermilion border of lip (C00.0-C00.2)
  • C50 Malignant neoplasm of breast applies to 57 codes
  • C51 Malignant neoplasm of vulva applies to 5 codes
    • carcinoma in situ of vulva (D07.1)
  • C52 Malignant neoplasm of vagina
    • carcinoma in situ of vagina (D07.2)
  • C53 Malignant neoplasm of cervix uteri applies to 4 codes
    • carcinoma in situ of cervix uteri (D06.-)
  • C58 Malignant neoplasm of placenta
    • chorioadenoma (destruens) (D39.2)
    • hydatidiform mole NOS (O01.9)
    • invasive hydatidiform mole (D39.2)
    • male choriocarcinoma NOS (C62.9-)
    • malignant hydatidiform mole (D39.2)
  • C61 Malignant neoplasm of prostate
    • malignant neoplasm of seminal vesicle (C63.7)
  • C64 Malignant neoplasm of kidney, except renal pelvis applies to 3 codes
    • malignant carcinoid tumor of the kidney (C7A.093)
    • malignant neoplasm of renal calyces (C65.-)
    • malignant neoplasm of renal pelvis (C65.-)
  • C66 Malignant neoplasm of ureter applies to 3 codes
    • malignant neoplasm of ureteric orifice of bladder (C67.6)
  • C68 Malignant neoplasm of other and unspecified urinary organs applies to 4 codes
    • malignant neoplasm of female genitourinary tract NOS (C57.9)
    • malignant neoplasm of male genitourinary tract NOS (C63.9)
  • C68.0 Malignant neoplasm of urethra
    • malignant neoplasm of urethral orifice of bladder (C67.5)
  • C69 Malignant neoplasm of eye and adnexa applies to 27 codes
    • malignant neoplasm of connective tissue of eyelid (C49.0)
    • malignant neoplasm of eyelid (skin) (C43.1-, C44.1-)
    • malignant neoplasm of optic nerve (C72.3-)
  • C69.2 Malignant neoplasm of retina applies to 3 codes
    • dark area on retina (D49.81)
    • neoplasm of unspecified behavior of retina and choroid (D49.81)
    • retinal freckle (D49.81)
  • C69.6 Malignant neoplasm of orbit applies to 3 codes
    • malignant neoplasm of orbital bone (C41.0)
  • C71 Malignant neoplasm of brain applies to 10 codes
    • malignant neoplasm of cranial nerves (C72.2-C72.5)
    • retrobulbar malignant neoplasm (C69.6-)
  • C71.5 Malignant neoplasm of cerebral ventricle
    • malignant neoplasm of fourth cerebral ventricle (C71.7)
  • C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system applies to 14 codes
    • malignant neoplasm of meninges (C70.-)
    • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • C75 Malignant neoplasm of other endocrine glands and related structures applies to 8 codes
    • malignant carcinoid tumors (C7A.0-)
    • malignant neoplasm of adrenal gland (C74.-)
    • malignant neoplasm of endocrine pancreas (C25.4)
    • malignant neoplasm of islets of Langerhans (C25.4)
    • malignant neoplasm of ovary (C56.-)
    • malignant neoplasm of testis (C62.-)
    • malignant neoplasm of thymus (C37)
    • malignant neoplasm of thyroid gland (C73)
    • malignant neuroendocrine tumors (C7A.-)
  • C76 Malignant neoplasm of other and ill-defined sites applies to 11 codes
    • malignant neoplasm of female genitourinary tract NOS (C57.9)
    • malignant neoplasm of male genitourinary tract NOS (C63.9)
    • malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)
    • malignant neoplasm of skin (C44.-)
    • malignant neoplasm of unspecified site NOS (C80.1)
  • C77 Secondary and unspecified malignant neoplasm of lymph nodes applies to 8 codes
    • malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)
    • mesentery metastasis of carcinoid tumor (C7B.04)
    • secondary carcinoid tumors of distant lymph nodes (C7B.01)
  • C78 Secondary malignant neoplasm of respiratory and digestive organs applies to 15 codes
    • secondary carcinoid tumors of liver (C7B.02)
    • secondary carcinoid tumors of peritoneum (C7B.04)
  • C79 Secondary malignant neoplasm of other and unspecified sites applies to 25 codes
    • secondary carcinoid tumors (C7B.-)
    • secondary neuroendocrine tumors (C7B.-)
  • C79.2 Secondary malignant neoplasm of skin
    • secondary Merkel cell carcinoma (C7B.1)
  • C79.5 Secondary malignant neoplasm of bone and bone marrow applies to 2 codes
    • secondary carcinoid tumors of bone (C7B.03)
  • C79.9 Secondary malignant neoplasm of unspecified site
    • carcinomatosis NOS (C80.0)
    • generalized cancer NOS (C80.0)
    • malignant (primary) neoplasm of unspecified site (C80.1)
  • C80 Malignant neoplasm without specification of site applies to 3 codes
    • malignant carcinoid tumor of unspecified site (C7A.00)
  • C80.1 Malignant (primary) neoplasm, unspecified
    • secondary malignant neoplasm of unspecified site (C79.9)
  • C81 Hodgkin lymphoma applies to 77 codes
    • personal history of Hodgkin lymphoma (Z85.71)
  • C81.4 Lymphocyte-rich Hodgkin lymphoma applies to 11 codes
    • nodular lymphocyte predominant Hodgkin lymphoma (C81.0-)
  • C82 Follicular lymphoma applies to 99 codes
    • mature T/NK-cell lymphomas (C84.-)
    • personal history of non-Hodgkin lymphoma (Z85.72)
  • C83 Non-follicular lymphoma applies to 78 codes
    • personal history of non-Hodgkin lymphoma (Z85.72)
  • C83.0 Small cell B-cell lymphoma applies to 11 codes
    • chronic lymphocytic leukemia (C91.1)
    • mature T/NK-cell lymphomas (C84.-)
    • Waldenström macroglobulinemia (C88.00)
  • C83.3 Diffuse large B-cell lymphoma applies to 12 codes
    • mediastinal (thymic) large B-cell lymphoma (C85.2-)
    • mature T/NK-cell lymphomas (C84.-)
  • C83.390 Primary central nervous system lymphoma
    • Primary central nervous system lymphoma, Burkitt (C83.79)
    • Primary central nervous system lymphoma, lymphoblastic (C83.59)
    • Primary central nervous system lymphoma, other (C83.89)
    • Primary central nervous system lymphoma, peripheral T-cell (C84.49)
  • C83.7 Burkitt lymphoma applies to 11 codes
    • mature B-cell leukemia Burkitt type (C91.A-)
  • C83.8 Other non-follicular lymphoma applies to 11 codes
    • mediastinal (thymic) large B-cell lymphoma (C85.2-)
    • T-cell rich B-cell lymphoma (C83.3-)
  • C84 Mature T/NK-cell lymphomas applies to 89 codes
    • personal history of non-Hodgkin lymphoma (Z85.72)
  • C84.0 Mycosis fungoides applies to 11 codes
    • peripheral T-cell lymphoma, not elsewhere classified (C84.4-)
  • C84.7 Anaplastic large cell lymphoma, ALK-negative applies to 12 codes
    • primary cutaneous CD30-positive T-cell proliferations (C86.6-)
  • C84.9 Mature T/NK-cell lymphomas, unspecified applies to 11 codes
    • mature T-cell lymphoma, not elsewhere classified (C84.4-)
  • C84.Z Other mature T/NK-cell lymphomas applies to 11 codes
    • angioimmunoblastic T-cell lymphoma (C86.50)
    • blastic NK-cell lymphoma (C86.40)
    • enteropathy-type T-cell lymphoma (C86.20)
    • extranodal NK-cell lymphoma, nasal type (C86.00)
    • hepatosplenic T-cell lymphoma (C86.10)
    • primary cutaneous CD30-positive T-cell proliferations (C86.60)
    • subcutaneous panniculitis-like T-cell lymphoma (C86.30)
    • T-cell leukemia (C91.1-)
  • C85 Other specified and unspecified types of non-Hodgkin lymphoma applies to 44 codes
    • other specified types of T/NK-cell lymphoma (C86.-)
    • personal history of non-Hodgkin lymphoma (Z85.72)
  • C86 Other specified types of T/NK-cell lymphoma applies to 14 codes
    • anaplastic large cell lymphoma, ALK negative (C84.7-)
    • anaplastic large cell lymphoma, ALK positive (C84.6-)
    • mature T/NK-cell lymphomas (C84.-)
    • other specified types of non-Hodgkin lymphoma (C85.8-)
  • C88 Malignant immunoproliferative diseases and certain other B-cell lymphomas applies to 12 codes
    • B-cell lymphoma, unspecified (C85.1-)
    • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
  • C88.0 Waldenstrom macroglobulinemia applies to 2 codes
    • small cell B-cell lymphoma (C83.0)
  • C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma] applies to 2 codes
    • high malignant (diffuse large B-cell) lymphoma (C83.3-)
  • C90 Multiple myeloma and malignant plasma cell neoplasms applies to 12 codes
    • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
  • C90.0 Multiple myeloma applies to 3 codes
  • C91 Lymphoid leukemia applies to 27 codes
    • personal history of leukemia (Z85.6)
  • C91.1 Chronic lymphocytic leukemia of B-cell type applies to 3 codes
    • lymphoplasmacytic lymphoma (C83.0-)
  • C91.A Mature B-cell leukemia Burkitt-type applies to 3 codes
  • C92 Myeloid leukemia applies to 30 codes
    • personal history of leukemia (Z85.6)
  • C92.0 Acute myeloblastic leukemia applies to 3 codes
    • acute exacerbation of chronic myeloid leukemia (C92.10)
    • refractory anemia with excess of blasts not in transformation (D46.2-)
  • C92.1 Chronic myeloid leukemia, BCR/ABL-positive applies to 3 codes
    • atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
    • chronic myelomonocytic leukemia (C93.1-)
    • chronic myeloproliferative disease (D47.1)
  • C93 Monocytic leukemia applies to 15 codes
    • personal history of leukemia (Z85.6)
  • C94 Other leukemias of specified cell type applies to 16 codes
    • leukemic reticuloendotheliosis (C91.4-)
    • myelodysplastic syndromes (D46.-)
    • personal history of leukemia (Z85.6)
    • plasma cell leukemia (C90.1-)
  • C94.4 Acute panmyelosis with myelofibrosis applies to 3 codes
    • myelofibrosis NOS (D75.81)
    • secondary myelofibrosis NOS (D75.81)
  • C95 Leukemia of unspecified cell type applies to 9 codes
    • personal history of leukemia (Z85.6)
  • C95.0 Acute leukemia of unspecified cell type applies to 3 codes
    • acute exacerbation of unspecified chronic leukemia (C95.10)
  • C96 Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue applies to 11 codes
    • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)
  • C96.0 Multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis
    • adult pulmonary Langerhans cell histiocytosis (J84.82)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
    • unifocal Langerhans-cell histiocytosis (C96.6)
  • C96.2 Malignant mast cell neoplasm applies to 4 codes
    • indolent mastocytosis (D47.02)
    • mast cell leukemia (C94.30)
    • mastocytosis (congenital) (cutaneous) (Q82.2)
  • C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
    • multifocal and multisystemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • unifocal Langerhans-cell histiocytosis (C96.6)
  • C96.6 Unifocal Langerhans-cell histiocytosis
    • multifocal and multisysemic (disseminated) Langerhans-cell histiocytosis (C96.0)
    • multifocal and unisystemic Langerhans-cell histiocytosis (C96.5)
  • D00 Carcinoma in situ of oral cavity, esophagus and stomach applies to 11 codes
  • D00.0 Carcinoma in situ of lip, oral cavity and pharynx applies to 9 codes
    • carcinoma in situ of aryepiglottic fold or interarytenoid fold, laryngeal aspect (D02.0)
    • carcinoma in situ of epiglottis NOS (D02.0)
    • carcinoma in situ of epiglottis suprahyoid portion (D02.0)
    • carcinoma in situ of skin of lip (D03.0, D04.0)
  • D01 Carcinoma in situ of other and unspecified digestive organs applies to 9 codes
  • D01.0 Carcinoma in situ of colon
    • carcinoma in situ of rectosigmoid junction (D01.1)
  • D01.3 Carcinoma in situ of anus and anal canal
    • anal intraepithelial neoplasia I and II [AIN I and AIN II] (K62.82)
    • carcinoma in situ of anal margin (D04.5)
    • carcinoma in situ of anal skin (D04.5)
    • carcinoma in situ of perianal skin (D04.5)
  • D01.4 Carcinoma in situ of other and unspecified parts of intestine applies to 2 codes
    • carcinoma in situ of ampulla of Vater (D01.5)
  • D02 Carcinoma in situ of middle ear and respiratory system applies to 7 codes
  • D02.0 Carcinoma in situ of larynx
    • carcinoma in situ of aryepiglottic fold or interarytenoid fold NOS (D00.08)
    • carcinoma in situ of hypopharyngeal aspect (D00.08)
    • carcinoma in situ of marginal zone (D00.08)
  • D02.3 Carcinoma in situ of other parts of respiratory system
    • carcinoma in situ of ear (external) (skin) (D04.2-)
    • carcinoma in situ of nose NOS (D09.8)
    • carcinoma in situ of skin of nose (D04.3)
  • D03.8 Melanoma in situ of other sites
    • carcinoma in situ of scrotum (D07.61)
  • D04 Carcinoma in situ of skin applies to 21 codes
    • erythroplasia of Queyrat (penis) NOS (D07.4)
    • melanoma in situ (D03.-)
  • D04.5 Carcinoma in situ of skin of trunk
    • carcinoma in situ of anus NOS (D01.3)
    • carcinoma in situ of scrotum (D07.61)
    • carcinoma in situ of skin of genital organs (D07.-)
  • D05 Carcinoma in situ of breast applies to 12 codes
    • carcinoma in situ of skin of breast (D04.5)
    • malignant neoplasm of breast (C50.-)
    • melanoma in situ of breast (skin) (D03.5)
    • Paget's disease of breast or nipple (C50.-)
  • D06 Carcinoma in situ of cervix uteri applies to 4 codes
    • cervical intraepithelial neoplasia II [CIN II] (N87.1)
    • cytologic evidence of malignancy of cervix without histologic confirmation (R87.614)
    • high grade squamous intraepithelial lesion (HGSIL) of cervix (R87.613)
    • melanoma in situ of cervix (D03.5)
    • moderate cervical dysplasia (N87.1)
  • D07 Carcinoma in situ of other and unspecified genital organs applies to 10 codes
    • melanoma in situ of trunk (D03.5)
  • D07.1 Carcinoma in situ of vulva
    • moderate dysplasia of vulva (N90.1)
    • vulvar intraepithelial neoplasia II [VIN II] (N90.1)
  • D07.2 Carcinoma in situ of vagina
    • moderate dysplasia of vagina (N89.1)
    • vaginal intraepithelial neoplasia II [VIN II] (N89.1)
  • D07.5 Carcinoma in situ of prostate
    • dysplasia (mild) (moderate) of prostate (N42.3-)
    • prostatic intraepithelial neoplasia II [PIN II] (N42.3-)
  • D09 Carcinoma in situ of other and unspecified sites applies to 9 codes
  • D09.2 Carcinoma in situ of eye applies to 3 codes
    • carcinoma in situ of skin of eyelid (D04.1-)
  • D09.3 Carcinoma in situ of thyroid and other endocrine glands
    • carcinoma in situ of endocrine pancreas (D01.7)
    • carcinoma in situ of ovary (D07.39)
    • carcinoma in situ of testis (D07.69)
  • D10.0 Benign neoplasm of lip
  • D10.39 Benign neoplasm of other parts of mouth
    • benign odontogenic neoplasms (D16.4-D16.5)
    • benign neoplasm of mucosa of lip (D10.0)
    • benign neoplasm of nasopharyngeal surface of soft palate (D10.6)
  • D10.4 Benign neoplasm of tonsil
    • benign neoplasm of lingual tonsil (D10.1)
    • benign neoplasm of pharyngeal tonsil (D10.6)
    • benign neoplasm of tonsillar fossa (D10.5)
    • benign neoplasm of tonsillar pillars (D10.5)
  • D10.5 Benign neoplasm of other parts of oropharynx
    • benign neoplasm of epiglottis NOS (D14.1)
    • benign neoplasm of epiglottis, suprahyoid portion (D14.1)
  • D11 Benign neoplasm of major salivary glands applies to 3 codes
    • benign neoplasms of minor salivary glands NOS (D10.39)
  • D12.1 Benign neoplasm of appendix
    • benign carcinoid tumor of the appendix (D3A.020)
  • D12.8 Benign neoplasm of rectum
    • benign carcinoid tumor of the rectum (D3A.026)
  • D12.9 Benign neoplasm of anus and anal canal
  • D13 Benign neoplasm of other and ill-defined parts of digestive system applies to 11 codes
    • benign stromal tumors of digestive system (D21.4)
  • D13.1 Benign neoplasm of stomach
    • benign carcinoid tumor of the stomach (D3A.092)
  • D13.2 Benign neoplasm of duodenum
    • benign carcinoid tumor of the duodenum (D3A.010)
  • D13.3 Benign neoplasm of other and unspecified parts of small intestine applies to 2 codes
    • benign carcinoid tumors of the small intestine (D3A.01-)
    • benign neoplasm of ileocecal valve (D12.0)
  • D13.6 Benign neoplasm of pancreas
    • benign neoplasm of endocrine pancreas (D13.7)
  • D14.0 Benign neoplasm of middle ear, nasal cavity and accessory sinuses
    • benign neoplasm of auricular canal (external) (D22.2-, D23.2-)
    • benign neoplasm of bone of ear (D16.4)
    • benign neoplasm of bone of nose (D16.4)
    • benign neoplasm of cartilage of ear (D21.0)
    • benign neoplasm of ear (external)(skin) (D22.2-, D23.2-)
    • benign neoplasm of nose NOS (D36.7)
    • benign neoplasm of skin of nose (D22.39, D23.39)
    • benign neoplasm of olfactory bulb (D33.3)
    • benign neoplasm of posterior margin of septum and choanae (D10.6)
    • polyp of accessory sinus (J33.8)
    • polyp of ear (middle) (H74.4)
    • polyp of nasal (cavity) (J33.-)
  • D14.1 Benign neoplasm of larynx
    • benign neoplasm of epiglottis, anterior aspect (D10.5)
    • polyp (nonadenomatous) of vocal cord or larynx (J38.1)
  • D14.3 Benign neoplasm of bronchus and lung applies to 3 codes
    • benign carcinoid tumor of the bronchus and lung (D3A.090)
  • D15 Benign neoplasm of other and unspecified intrathoracic organs applies to 5 codes
    • benign neoplasm of mesothelial tissue (D19.-)
  • D15.0 Benign neoplasm of thymus
    • benign carcinoid tumor of the thymus (D3A.091)
  • D15.1 Benign neoplasm of heart
    • benign neoplasm of great vessels (D21.3)
  • D16 Benign neoplasm of bone and articular cartilage applies to 18 codes
    • benign neoplasm of connective tissue of ear (D21.0)
    • benign neoplasm of connective tissue of eyelid (D21.0)
    • benign neoplasm of connective tissue of larynx (D14.1)
    • benign neoplasm of connective tissue of nose (D14.0)
    • benign neoplasm of synovia (D21.-)
  • D16.6 Benign neoplasm of vertebral column
    • benign neoplasm of sacrum and coccyx (D16.8)
  • D17.5 Benign lipomatous neoplasm of intra-abdominal organs
    • benign lipomatous neoplasm of peritoneum and retroperitoneum (D17.79)
  • D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum applies to 2 codes
    • benign lipomatous neoplasm of peritoneum and retroperitoneum (D17.79)
    • benign neoplasm of mesothelial tissue (D19.-)
  • D21 Other benign neoplasms of connective and other soft tissue applies to 12 codes
    • benign neoplasm of articular cartilage (D16.-)
    • benign neoplasm of cartilage of larynx (D14.1)
    • benign neoplasm of cartilage of nose (D14.0)
    • benign neoplasm of connective tissue of breast (D24.-)
    • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
    • benign neoplasm of peritoneum (D20.1)
    • benign neoplasm of retroperitoneum (D20.0)
    • benign neoplasm of uterine ligament, any (D28.2)
    • benign neoplasm of vascular tissue (D18.-)
    • hemangioma (D18.0-)
    • lipomatous neoplasm (D17.-)
    • lymphangioma (D18.1)
    • uterine leiomyoma (D25.-)
  • D21.0 Benign neoplasm of connective and other soft tissue of head, face and neck
    • benign neoplasm of connective tissue of orbit (D31.6-)
  • D21.3 Benign neoplasm of connective and other soft tissue of thorax
    • benign neoplasm of heart (D15.1)
    • benign neoplasm of mediastinum (D15.2)
    • benign neoplasm of thymus (D15.0)
  • D21.5 Benign neoplasm of connective and other soft tissue of pelvis
    • benign neoplasm of any uterine ligament (D28.2)
    • uterine leiomyoma (D25.-)
  • D23 Other benign neoplasms of skin applies to 20 codes
  • D23.0 Other benign neoplasm of skin of lip
    • benign neoplasm of vermilion border of lip (D10.0)
  • D23.5 Other benign neoplasm of skin of trunk
    • benign neoplasm of anus NOS (D12.9)
  • D28 Benign neoplasm of other and unspecified female genital organs applies to 5 codes
  • D29.1 Benign neoplasm of prostate
    • enlarged prostate (N40.-)
  • D30.0 Benign neoplasm of kidney applies to 3 codes
    • benign carcinoid tumor of the kidney (D3A.093)
    • benign neoplasm of renal calyces (D30.1-)
    • benign neoplasm of renal pelvis (D30.1-)
  • D30.2 Benign neoplasm of ureter applies to 3 codes
    • benign neoplasm of ureteric orifice of bladder (D30.3)
  • D30.4 Benign neoplasm of urethra
    • benign neoplasm of urethral orifice of bladder (D30.3)
  • D31 Benign neoplasm of eye and adnexa applies to 24 codes
    • benign neoplasm of connective tissue of eyelid (D21.0)
    • benign neoplasm of optic nerve (D33.3)
    • benign neoplasm of skin of eyelid (D22.1-, D23.1-)
  • D31.2 Benign neoplasm of retina applies to 3 codes
    • dark area on retina (D49.81)
    • hemangioma of retina (D49.81)
    • neoplasm of unspecified behavior of retina and choroid (D49.81)
    • retinal freckle (D49.81)
  • D31.6 Benign neoplasm of unspecified site of orbit applies to 3 codes
    • benign neoplasm of orbital bone (D16.4)
  • D33 Benign neoplasm of brain and other parts of central nervous system applies to 7 codes
    • angioma (D18.0-)
    • benign neoplasm of meninges (D32.-)
    • benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
    • hemangioma (D18.0-)
    • neurofibromatosis (Q85.0-)
    • retro-ocular benign neoplasm (D31.6-)
  • D33.0 Benign neoplasm of brain, supratentorial
    • benign neoplasm of fourth ventricle (D33.1)
  • D35 Benign neoplasm of other and unspecified endocrine glands applies to 11 codes
    • benign neoplasm of endocrine pancreas (D13.7)
    • benign neoplasm of ovary (D27.-)
    • benign neoplasm of testis (D29.2.-)
    • benign neoplasm of thymus (D15.0)
  • D36.0 Benign neoplasm of lymph nodes
  • D36.1 Benign neoplasm of peripheral nerves and autonomic nervous system applies to 8 codes
    • benign neoplasm of peripheral nerves of orbit (D31.6-)
    • neurofibromatosis (Q85.0-)
  • Block note Block D37-D48 Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes applies to 137 codes
    • neoplasms of unspecified behavior (D49.-)
  • D37 Neoplasm of uncertain behavior of oral cavity and digestive organs applies to 17 codes
    • stromal tumors of uncertain behavior of digestive system (D48.1-)
  • D37.0 Neoplasm of uncertain behavior of lip, oral cavity and pharynx applies to 9 codes
    • neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold, laryngeal aspect (D38.0)
    • neoplasm of uncertain behavior of epiglottis NOS (D38.0)
    • neoplasm of uncertain behavior of skin of lip (D48.5)
    • neoplasm of uncertain behavior of suprahyoid portion of epiglottis (D38.0)
  • D37.8 Neoplasm of uncertain behavior of other specified digestive organs
    • neoplasm of uncertain behavior of anal margin (D48.5)
    • neoplasm of uncertain behavior of anal skin (D48.5)
    • neoplasm of uncertain behavior of perianal skin (D48.5)
  • D38 Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs applies to 7 codes
    • neoplasm of uncertain behavior of heart (D48.7)
  • D38.0 Neoplasm of uncertain behavior of larynx
    • neoplasm of uncertain behavior of aryepiglottic fold or interarytenoid fold NOS (D37.05)
    • neoplasm of uncertain behavior of hypopharyngeal aspect of aryepiglottic fold (D37.05)
    • neoplasm of uncertain behavior of marginal zone of aryepiglottic fold (D37.05)
  • D38.5 Neoplasm of uncertain behavior of other respiratory organs
    • neoplasm of uncertain behavior of ear (external) (skin) (D48.5)
    • neoplasm of uncertain behavior of nose NOS (D48.7)
    • neoplasm of uncertain behavior of skin of nose (D48.5)
  • D39.2 Neoplasm of uncertain behavior of placenta
    • hydatidiform mole NOS (O01.9)
  • D41.0 Neoplasm of uncertain behavior of kidney applies to 3 codes
    • neoplasm of uncertain behavior of renal pelvis (D41.1-)
  • D43 Neoplasm of uncertain behavior of brain and central nervous system applies to 7 codes
    • neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system (D48.2)
  • D43.0 Neoplasm of uncertain behavior of brain, supratentorial
    • neoplasm of uncertain behavior of fourth ventricle (D43.1)
  • D44 Neoplasm of uncertain behavior of endocrine glands applies to 11 codes
    • multiple endocrine adenomatosis (E31.2-)
    • multiple endocrine neoplasia (E31.2-)
    • neoplasm of uncertain behavior of endocrine pancreas (D37.8)
    • neoplasm of uncertain behavior of ovary (D39.1-)
    • neoplasm of uncertain behavior of testis (D40.1-)
    • neoplasm of uncertain behavior of thymus (D38.4)
  • D45 Polycythemia vera
    • familial polycythemia (D75.0)
    • secondary polycythemia (D75.1)
  • D46.Z Other myelodysplastic syndromes
    • chronic myelomonocytic leukemia (C93.1-)
  • D47.0 Mast cell neoplasms of uncertain behavior applies to 3 codes
    • congenital cutaneous mastocytosis (Q82.2)
    • histiocytic neoplasms of uncertain behavior (D47.Z9)
    • malignant mast cell neoplasm (C96.2-)
  • D47.01 Cutaneous mastocytosis
    • congenital (diffuse) (maculopapular) cutaneous mastocytosis (Q82.2)
    • congenital urticaria pigmentosa (Q82.2)
    • extracutaneous mastocytoma (D47.09)
  • D47.02 Systemic mastocytosis
    • aggressive systemic mastocytosis (C96.21)
    • mast cell leukemia (C94.3-)
  • D47.1 Chronic myeloproliferative disease
    • atypical chronic myeloid leukemia BCR/ABL-negative (C92.2-)
    • chronic myeloid leukemia BCR/ABL-positive (C92.1-)
    • myelofibrosis NOS (D75.81)
    • myelophthisic anemia (D61.82)
    • myelophthisis (D61.82)
    • secondary myelofibrosis NOS (D75.81)
  • D47.4 Osteomyelofibrosis
  • D48 Neoplasm of uncertain behavior of other and unspecified sites applies to 21 codes
    • neurofibromatosis (nonmalignant) (Q85.0-)
  • D48.0 Neoplasm of uncertain behavior of bone and articular cartilage
    • neoplasm of uncertain behavior of cartilage of ear (D48.1-)
    • neoplasm of uncertain behavior of cartilage of larynx (D38.0)
    • neoplasm of uncertain behavior of cartilage of nose (D38.5)
    • neoplasm of uncertain behavior of connective tissue of eyelid (D48.1-)
    • neoplasm of uncertain behavior of synovia (D48.1-)
  • D48.1 Neoplasm of uncertain behavior of connective and other soft tissue applies to 11 codes
    • neoplasm of uncertain behavior of articular cartilage (D48.0)
    • neoplasm of uncertain behavior of cartilage of larynx (D38.0)
    • neoplasm of uncertain behavior of cartilage of nose (D38.5)
    • neoplasm of uncertain behavior of connective tissue of breast (D48.6-)
  • D48.2 Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
    • neoplasm of uncertain behavior of peripheral nerves of orbit (D48.7)
  • D48.5 Neoplasm of uncertain behavior of skin
    • neoplasm of uncertain behavior of anus NOS (D37.8)
    • neoplasm of uncertain behavior of skin of genital organs (D39.8, D40.8)
    • neoplasm of uncertain behavior of vermilion border of lip (D37.0)
  • D48.6 Neoplasm of uncertain behavior of breast applies to 3 codes
    • neoplasm of uncertain behavior of skin of breast (D48.5)
  • D48.7 Neoplasm of uncertain behavior of other specified sites
    • neoplasm of uncertain behavior of connective tissue (D48.1-)
    • neoplasm of uncertain behavior of skin of eyelid (D48.5)
  • D49.0 Neoplasm of unspecified behavior of digestive system
    • neoplasm of unspecified behavior of margin of anus (D49.2)
    • neoplasm of unspecified behavior of perianal skin (D49.2)
    • neoplasm of unspecified behavior of skin of anus (D49.2)
  • D49.2 Neoplasm of unspecified behavior of bone, soft tissue, and skin
    • neoplasm of unspecified behavior of anal canal (D49.0)
    • neoplasm of unspecified behavior of anus NOS (D49.0)
    • neoplasm of unspecified behavior of bone marrow (D49.89)
    • neoplasm of unspecified behavior of cartilage of larynx (D49.1)
    • neoplasm of unspecified behavior of cartilage of nose (D49.1)
    • neoplasm of unspecified behavior of connective tissue of breast (D49.3)
    • neoplasm of unspecified behavior of skin of genital organs (D49.59)
    • neoplasm of unspecified behavior of vermilion border of lip (D49.0)
  • D49.3 Neoplasm of unspecified behavior of breast
    • neoplasm of unspecified behavior of skin of breast (D49.2)
  • D49.6 Neoplasm of unspecified behavior of brain
    • neoplasm of unspecified behavior of cerebral meninges (D49.7)
    • neoplasm of unspecified behavior of cranial nerves (D49.7)
  • D49.7 Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
    • neoplasm of unspecified behavior of peripheral, sympathetic, and parasympathetic nerves and ganglia (D49.2)
  • D49.8 Neoplasm of unspecified behavior of other specified sites applies to 2 codes
    • neoplasm of unspecified behavior of eyelid (skin) (D49.2)
    • neoplasm of unspecified behavior of eyelid cartilage (D49.2)
    • neoplasm of unspecified behavior of great vessels (D49.2)
    • neoplasm of unspecified behavior of optic nerve (D49.7)

The first view lists notes printed in this chapter (a note on a category or block applies to every code beneath it). The second lists codes of this chapter named by Excludes1 Notes anywhere in the Tabular List, including notes in other chapters.

Questions About Excludes1 Notes

What does an Excludes1 note mean?

An Excludes1 note means “NOT CODED HERE!”: the excluded code should never be used at the same time as the code above the note. It is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition (Section I.A.12.a). The FY 2027 Tabular List has 5,411 of them; 5,284 name other codes, with 5,710 references to 3,528 distinct codes, categories and ranges.

Is there any exception to an Excludes1 note?

Yes: when the two conditions are unrelated to each other. The Guidelines’ example is F45.8, whose Excludes1 note names sleep related teeth grinding (G47.63). A patient with psychogenic dysmenorrhea (an inclusion term of F45.8) and teeth grinding may have both codes reported. If it is not clear whether the conditions are related, query the provider.

Related References

Source: FY 2027 ICD-10-CM Tabular List (CMS and NCHS) and the ICD-10-CM Official Guidelines for Coding and Reporting FY 2027, Section I.A. ICD List is not affiliated with CMS or NCHS.