Not Valid for Submission
C45 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of mesothelioma. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding for Mesothelioma
Non-specific codes like C45 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for mesothelioma:
- MESOTHELIOMA MALIGNANT-. a type of mesothelioma with a tendency to metastasize. the majority of the tumors originate from either the pleura or peritoneum but which may also orginate in the pericardium or testicular tissue. it is associated with asbestos exposure. somatic mutations identified in wt1 bcl10 cdkn2a nf2 and bap1 genes are associated with the malignancy. omim: 156240
- MESOTHELIOMA-. a tumor derived from mesothelial tissue peritoneum pleura pericardium. it appears as broad sheets of cells with some regions containing spindle shaped sarcoma like cells and other regions showing adenomatous patterns. pleural mesotheliomas have been linked to exposure to asbestos. dorland 27th ed
- MESOTHELIOMA CYSTIC-. a peritoneal mesothelioma affecting mainly young females and producing cysts of variable size and number lined by a single layer of benign mesothelial cells. the disease follows a benign course and is compatible with a normal life expectancy requiring occasionally partial excision or decompression for relief of pain or other symptoms. malignant potential is exceptional. from holland et al. cancer medicine 3d ed p1345
- SOLITARY FIBROUS TUMOR PLEURAL-. a rare neoplasm usually benign derived from mesenchymal fibroblasts located in the submesothelial lining of the pleura. it spite of its various synonyms it has no features of mesothelial cells and is not related to malignant mesothelioma or asbestos exposure.
Information for Patients
The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma, also known as malignant mesothelioma, is cancer of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs.
Malignant mesothelioma is rare but serious. Most people who get it have worked on jobs where they inhaled asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form.
- Trouble breathing
- Pain under the rib cage
- Pain, swelling, or lumps in the abdomen
- Weight loss for no known reason
Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. Your doctor uses imaging tests and a biopsy to make the diagnosis. Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment may include surgery, radiation, chemotherapy, and/or targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells.
NIH: National Cancer Institute
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