2022 ICD-10-CM Code C45

Mesothelioma

Version 2021

Not Valid for Submission

ICD-10:C45
Short Description:Mesothelioma
Long Description:Mesothelioma

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of mesothelial and soft tissue (C45-C49)
      • Mesothelioma (C45)

C45 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of mesothelioma. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding for Mesothelioma

Non-specific codes like C45 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for mesothelioma:

  • BILLABLE CODE - Use C45.0 for Mesothelioma of pleura
  • BILLABLE CODE - Use C45.1 for Mesothelioma of peritoneum
  • BILLABLE CODE - Use C45.2 for Mesothelioma of pericardium
  • BILLABLE CODE - Use C45.7 for Mesothelioma of other sites
  • BILLABLE CODE - Use C45.9 for Mesothelioma, unspecified

Clinical Information

Information for Patients


Mesothelioma

The tissue that lines your lungs, stomach, heart, and other organs is called mesothelium. Mesothelioma, also known as malignant mesothelioma, is cancer of that tissue. It usually starts in the lungs, but can also start in the abdomen or other organs.

Malignant mesothelioma is rare but serious. Most people who get it have worked on jobs where they inhaled asbestos particles. After being exposed to asbestos, it usually takes a long time for the disease to form.

Symptoms include

Sometimes it is hard to tell the difference between malignant mesothelioma and lung cancer. Your doctor uses imaging tests and a biopsy to make the diagnosis. Malignant mesothelioma is often found when it is advanced. This makes it harder to treat. Treatment may include surgery, radiation, chemotherapy, and/or targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)