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  3. 2025 Secondary Malignant Neoplasms ICD-10-CM Codes

2025 Secondary Malignant Neoplasms ICD-10-CM Codes

The 2025 Secondary Malignant Neoplasms ICD-10-CM Codes list includes 37 codes for cancers that have metastasized from the primary site. Coders must carefully identify and document both the primary malignant neoplasm and all secondary metastatic locations. Correct sequencing and code assignment are critical for proper claims submission, treatment planning, and Medicare compliance.

Secondary and unspecified malignant neoplasm of lymph nodes (C77)

  • C77.0 - Secondary and unspecified malignant neoplasm of lymph nodes of head, face and neck Billable

  • C77.1 - Secondary and unspecified malignant neoplasm of intrathoracic lymph nodes Billable

  • C77.2 - Secondary and unspecified malignant neoplasm of intra-abdominal lymph nodes Billable

  • C77.3 - Secondary and unspecified malignant neoplasm of axilla and upper limb lymph nodes Billable

  • C77.4 - Secondary and unspecified malignant neoplasm of inguinal and lower limb lymph nodes Billable

  • C77.5 - Secondary and unspecified malignant neoplasm of intrapelvic lymph nodes Billable

  • C77.8 - Secondary and unspecified malignant neoplasm of lymph nodes of multiple regions Billable

  • C77.9 - Secondary and unspecified malignant neoplasm of lymph node, unspecified Billable

Secondary malignant neoplasm of other and unspecified sites (C79)

  • C79.0 - Secondary malignant neoplasm of kidney and renal pelvis Non-Billable

  • C79.10 - Secondary malignant neoplasm of unspecified urinary organs Billable

  • C79.11 - Secondary malignant neoplasm of bladder Billable

  • C79.19 - Secondary malignant neoplasm of other urinary organs Billable

  • C79.2 - Secondary malignant neoplasm of skin Billable

  • C79.31 - Secondary malignant neoplasm of brain Billable

  • C79.32 - Secondary malignant neoplasm of cerebral meninges Billable

  • C79.40 - Secondary malignant neoplasm of unspecified part of nervous system Billable

  • C79.49 - Secondary malignant neoplasm of other parts of nervous system Billable

  • C79.51 - Secondary malignant neoplasm of bone Billable

  • C79.52 - Secondary malignant neoplasm of bone marrow Billable

  • C79.6 - Secondary malignant neoplasm of ovary Non-Billable

  • C79.7 - Secondary malignant neoplasm of adrenal gland Non-Billable

  • C79.8 - Secondary malignant neoplasm of other specified sites Non-Billable

  • C79.81 - Secondary malignant neoplasm of breast Billable

  • C79.82 - Secondary malignant neoplasm of genital organs Billable

  • C79.89 - Secondary malignant neoplasm of other specified sites Billable

  • C79.9 - Secondary malignant neoplasm of unspecified site Billable

Secondary malignant neoplasm of respiratory and digestive organs (C78)

  • C78.0 - Secondary malignant neoplasm of lung Non-Billable

  • C78.1 - Secondary malignant neoplasm of mediastinum Billable

  • C78.2 - Secondary malignant neoplasm of pleura Billable

  • C78.30 - Secondary malignant neoplasm of unspecified respiratory organ Billable

  • C78.39 - Secondary malignant neoplasm of other respiratory organs Billable

  • C78.4 - Secondary malignant neoplasm of small intestine Billable

  • C78.5 - Secondary malignant neoplasm of large intestine and rectum Billable

  • C78.6 - Secondary malignant neoplasm of retroperitoneum and peritoneum Billable

  • C78.7 - Secondary malignant neoplasm of liver and intrahepatic bile duct Billable

  • C78.80 - Secondary malignant neoplasm of unspecified digestive organ Billable

  • C78.89 - Secondary malignant neoplasm of other digestive organs Billable