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  6. 2024 ICD-10-CM Code D48.2

2024 ICD-10-CM Diagnosis Code D48.2

Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system

ICD-10-CM Code:
D48.2
ICD-10 Code for:
Neoplm of uncrt behav of prph nerves and autonm nervous sys
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Neoplasms
    (C00–D49)
    • Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
      (D37-D48)
      • Neoplasm of uncertain behavior of other and unspecified sites
        (D48)

D48.2 is a billable diagnosis code used to specify a medical diagnosis of neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic brachial plexus ; Neoplasm, neoplastic ganglia [See Also: Neoplasm, nerve, peripheral] ; Neoplasm, neoplastic lumbosacral plexus ; Neoplasm, neoplastic nerve (ganglion) ; Neoplasm, neoplastic nerve (ganglion) autonomic NEC [See Also: Neoplasm, nerve, peripheral] ; Neoplasm, neoplastic nerve (ganglion) brachial ; Neoplasm, neoplastic nerve (ganglion) femoral ; etc

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Neoplasm of uncertain behavior of peripheral nerve
  • Neoplasm of uncertain behavior of peripheral nerves and peripheral autonomic nervous system

Clinical Classification

Clinical Information

  • Brachial Plexus

    the large network of nerve fibers which distributes the innervation of the upper extremity. the brachial plexus extends from the neck into the axilla. in humans, the nerves of the plexus usually originate from the lower cervical and the first thoracic spinal cord segments (c5-c8 and t1), but variations are not uncommon.

  • Brachial Plexus Block

    a blocking of neural conduction in the network of nerve fibers innervating the upper extremity.

  • Brachial Plexus Neuritis

    a syndrome associated with inflammation of the brachial plexus. clinical features include severe pain in the shoulder region which may be accompanied by muscle weakness and loss of sensation in the upper extremity. this condition may be associated with virus diseases; immunization; surgery; heroin use (see heroin dependence); and other conditions. the term brachial neuralgia generally refers to pain associated with brachial plexus injury. (from adams et al., principles of neurology, 6th ed, pp1355-6)

  • Brachial Plexus Neuropathies

    diseases of the cervical (and first thoracic) roots, nerve trunks, cords, and peripheral nerve components of the brachial plexus. clinical manifestations include regional pain, paresthesia; muscle weakness, and decreased sensation (hypesthesia) in the upper extremity. these disorders may be associated with trauma (including birth injuries); thoracic outlet syndrome; neoplasms; neuritis; radiotherapy; and other conditions. (from adams et al., principles of neurology, 6th ed, pp1351-2)

  • Lumbosacral Plexus

    the lumbar and sacral plexuses taken together. the fibers of the lumbosacral plexus originate in the lumbar and upper sacral spinal cord (l1 to s3) and innervate the lower extremities.

  • Sciatic Nerve

    a nerve which originates in the lumbar and sacral spinal cord (l4 to s3) and supplies motor and sensory innervation to the lower extremity. the sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. it has two major branches, the tibial nerve and the peroneal nerve.

  • Sciatic Neuropathy

    disease or damage involving the sciatic nerve, which divides into the peroneal nerve and tibial nerve (see also peroneal neuropathies and tibial neuropathy). clinical manifestations may include sciatica or pain localized to the hip, paresis or paralysis of posterior thigh muscles and muscles innervated by the peroneal and tibial nerves, and sensory loss involving the lateral and posterior thigh, posterior and lateral leg, and sole of the foot. the sciatic nerve may be affected by trauma; ischemia; collagen diseases; and other conditions. (from adams et al., principles of neurology, 6th ed, p1363)

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • neoplasm of uncertain behavior of peripheral nerves of orbit D48.7

Convert D48.2 to ICD-9-CM

  • ICD-9-CM Code: 238.1 - Unc behav neo soft tissu
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Table of Neoplasms

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary		 Malignant
Secondary		 CaInSitu Benign Uncertain
Behavior		 Unspecified
Behavior
»Neoplasm, neoplastic
  »brachial plexus
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »ganglia [See Also: Neoplasm, nerve, peripheral]
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »lumbosacral plexus
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »autonomic NEC [See Also: Neoplasm, nerve, peripheral]
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »brachial
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »femoral
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »ganglion NEC [See Also: Neoplasm, nerve, peripheral]
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »intercostal
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »lumbar
C47.6C79.89 D36.17D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »median
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »obturator
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »parasympathetic NEC
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »abdomen
C47.4C79.89 D36.15D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »abdominal wall
C47.4C79.89 D36.15D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »ankle
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »antecubital fossa or space
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »arm
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »auricle (ear)
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »axilla
C47.3C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »back
C47.6C79.89 D36.17D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »buttock
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »calf
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »cervical region
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »cheek
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »chest (wall)
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »chin
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »ear (external)
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »elbow
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »extrarectal
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »extremity
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »extremity
        »lower
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »extremity
        »upper
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »eyelid
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »face
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »finger
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »flank
C47.6C79.89 D36.17D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »foot
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »forearm
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »forehead
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »gluteal region
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »groin
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »hand
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »head
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »heel
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »hip
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »infraclavicular region
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »inguinal (canal) (region)
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »intrathoracic
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »ischiorectal fossa
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »knee
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »leg
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »limb NEC
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »limb NEC
        »lower
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »limb NEC
        »upper
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »nates
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »neck
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »pararectal
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »paraurethral
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »paravaginal
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »pelvis (floor)
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »pelvoabdominal
C47.8C79.89 D36.17D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »perineum
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »perirectal (tissue)
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »periurethral (tissue)
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »popliteal fossa or space
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »presacral
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »pterygoid fossa
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »rectovaginal septum or wall
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »rectovesical
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »sacrococcygeal region
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »scalp
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »scapular region
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »shoulder
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »submental
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »supraclavicular region
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »temple
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »temporal region
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »thigh
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »thoracic (duct) (wall)
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »thorax
C47.3C79.89 D36.14D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »thumb
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »toe
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »trunk
C47.6C79.89 D36.17D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »umbilicus
C47.4C79.89 D36.15D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »vesicorectal
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »peripheral NEC
      »wrist
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »radial
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »sacral
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »sciatic
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »spinal NEC
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »sympathetic NEC [See Also: Neoplasm, nerve, peripheral]
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »nerve (ganglion)
    »ulnar
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »peripheral nerve NEC
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »plexus
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »plexus
    »brachial
C47.1C79.89 D36.12D48.2D49.2
»Neoplasm, neoplastic
  »plexus
    »cervical
C47.0C79.89 D36.11D48.2D49.2
»Neoplasm, neoplastic
  »plexus
    »lumbosacral
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »plexus
    »sacral
C47.5C79.89 D36.16D48.2D49.2
»Neoplasm, neoplastic
  »sciatic nerve
C47.2C79.89 D36.13D48.2D49.2
»Neoplasm, neoplastic
  »spine, spinal (column)
    »nerve (root)
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »spine, spinal (column)
    »root
C47.9C79.89 D36.10D48.2D49.2
»Neoplasm, neoplastic
  »sympathetic nerve or nervous system NEC
C47.9C79.89 D36.10D48.2D49.2

Patient Education


Autonomic Nervous System Disorders

Your autonomic nervous system is the part of your nervous system that controls involuntary actions, such as the beating of your heart and the widening or narrowing of your blood vessels. When something goes wrong in this system, it can cause serious problems, including:

  • Blood pressure problems
  • Heart problems
  • Trouble with breathing and swallowing
  • Erectile dysfunction in men

Autonomic nervous system disorders can occur alone or as the result of another disease, such as Parkinson's disease, alcoholism and diabetes. Problems can affect either part of the system, as in complex regional pain syndromes, or all of the system. Some types are temporary, but many worsen over time. When they affect your breathing or heart function, these disorders can be life-threatening.

Some autonomic nervous system disorders get better when an underlying disease is treated. Often, however, there is no cure. In that case, the goal of treatment is to improve symptoms.

NIH: National Institute of Neurological Disorders and Stroke


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.