2024 ICD-10-CM Diagnosis Code D37.8

Neoplasm of uncertain behavior of other specified digestive organs

ICD-10-CM Code:
D37.8
ICD-10 Code for:
Neoplasm of uncertain behavior of oth digestive organs
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Neoplasms
    (C00–D49)
    • Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
      (D37-D48)
      • Neoplasm of uncertain behavior of oral cavity and digestive organs
        (D37)

D37.8 is a billable diagnosis code used to specify a medical diagnosis of neoplasm of uncertain behavior of other specified digestive organs. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic anorectum, anorectal (junction) ; Neoplasm, neoplastic anus, anal ; Neoplasm, neoplastic anus, anal canal ; Neoplasm, neoplastic anus, anal cloacogenic zone ; Neoplasm, neoplastic anus, anal sphincter ; Neoplasm, neoplastic canal ; Neoplasm, neoplastic canal anal ; etc

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Carcinoid tumor of intestine
  • Carcinoid tumor of pancreas
  • Diffuse leiomyomatosis of esophagus
  • Gastrinoma
  • Gastrinoma of pancreas
  • Glucagonoma syndrome
  • Necrolytic migratory erythema
  • Neoplasm of body of pancreas
  • Neoplasm of cervical esophagus
  • Neoplasm of head of pancreas
  • Neoplasm of muscle of perineum
  • Neoplasm of tail of pancreas
  • Neoplasm of uncertain behavior of abdominal esophagus
  • Neoplasm of uncertain behavior of anal canal
  • Neoplasm of uncertain behavior of anal canal and sphincter
  • Neoplasm of uncertain behavior of anus
  • Neoplasm of uncertain behavior of body of pancreas
  • Neoplasm of uncertain behavior of cervical esophagus
  • Neoplasm of uncertain behavior of esophagus
  • Neoplasm of uncertain behavior of head of pancreas
  • Neoplasm of uncertain behavior of intestinal tract
  • Neoplasm of uncertain behavior of islets of Langerhans
  • Neoplasm of uncertain behavior of lower third of esophagus
  • Neoplasm of uncertain behavior of mediastinum
  • Neoplasm of uncertain behavior of middle third of esophagus
  • Neoplasm of uncertain behavior of muscle of perineum
  • Neoplasm of uncertain behavior of muscle of trunk
  • Neoplasm of uncertain behavior of pancreas
  • Neoplasm of uncertain behavior of pancreatic duct
  • Neoplasm of uncertain behavior of spleen
  • Neoplasm of uncertain behavior of tail of pancreas
  • Neoplasm of uncertain behavior of thoracic esophagus
  • Neoplasm of uncertain behavior of upper third of esophagus
  • Somatostatinoma

Clinical Classification

Clinical Information

  • Barrett Esophagus

    a condition with damage to the lining of the lower esophagus resulting from chronic acid reflux (esophagitis, reflux). through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the intestine or the salmon-pink mucosa of the stomach. barrett's columnar epithelium is a marker for severe reflux and precursor to adenocarcinoma of the esophagus.
  • Esophageal Motility Disorders

    disorders affecting the motor function of the upper esophageal sphincter; lower esophageal sphincter; the esophagus body, or a combination of these parts. the failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (gastroesophageal reflux). other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus).
  • Esophageal Mucosa

    circular innermost layer of the esophagus wall that mediates esophageal peristalsis which pushes ingested food bolus toward the stomach.
  • Esophageal Neoplasms

    tumors or cancer of the esophagus.
  • Esophagus

    the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.
  • Carcinoma, Pancreatic Ductal

    carcinoma that arises from the pancreatic ducts. it accounts for the majority of cancers derived from the pancreas.
  • Cystic Fibrosis

    an autosomal recessive genetic disease of the exocrine glands. it is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator expressed in several organs including the lung, the pancreas, the biliary system, and the sweat glands. cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in airway obstruction; chronic respiratory infections; pancreatic insufficiency; maldigestion; salt depletion; and heat prostration.
  • Insulin Infusion Systems

    portable or implantable devices for infusion of insulin. includes open-loop systems which may be patient-operated or controlled by a pre-set program and are designed for constant delivery of small quantities of insulin, increased during food ingestion, and closed-loop systems which deliver quantities of insulin automatically based on an electronic glucose sensor.
  • Islets of Langerhans

    irregular microscopic structures consisting of cords of endocrine cells that are scattered throughout the pancreas among the exocrine acini. each islet is surrounded by connective tissue fibers and penetrated by a network of capillaries. there are four major cell types. the most abundant beta cells (50-80%) secrete insulin. alpha cells (5-20%) secrete glucagon. pp cells (10-35%) secrete pancreatic polypeptide. delta cells (~5%) secrete somatostatin.
  • Nesidioblastosis

    an inherited autosomal recessive syndrome characterized by the disorganized formation of new islets in the pancreas and congenital hyperinsulinism. it is due to focal hyperplasia of pancreatic islet cells budding off from the ductal structures and forming new islets of langerhans. mutations in the islet cells involve the potassium channel gene kcnj11 or the atp-binding cassette transporter gene abcc8, both on chromosome 11.
  • Pancreas

    a nodular organ in the abdomen that contains a mixture of endocrine glands and exocrine glands. the small endocrine portion consists of the islets of langerhans secreting a number of hormones into the blood stream. the large exocrine portion (exocrine pancreas) is a compound acinar gland that secretes several digestive enzymes into the pancreatic ductal system that empties into the duodenum.
  • Pancreas Divisum

    anatomic variants in pancreatic ducts characterized by failure of fusion of the ventral and dorsal endodermal buds. pancreas divisum results in inadequate or no communication between dorsal and ventral ducts. while most cases are asymptomatic, it may be associated with recurrent pancreatitis.
  • Pancreas Transplantation

    the transference of a pancreas from one human or animal to another.
  • Pancreas, Artificial

    devices for simulating the activity of the pancreas. they can be either electromechanical, consisting of a glucose sensor, computer, and insulin pump or bioartificial, consisting of isolated islets of langerhans in an artificial membrane.
  • Pancreas, Exocrine

    the major component (about 80%) of the pancreas composed of acinar functional units of tubular and spherical cells. the acinar cells synthesize and secrete several digestive enzymes such as trypsinogen; lipase; amylase; and ribonuclease. secretion from the exocrine pancreas drains into the pancreatic ductal system and empties into the duodenum.
  • Pancreatic Neoplasms

    tumors or cancer of the pancreas. depending on the types of islet cells present in the tumors, various hormones can be secreted: glucagon from pancreatic alpha cells; insulin from pancreatic beta cells; and somatostatin from the somatostatin-secreting cells. most are malignant except the insulin-producing tumors (insulinoma).
  • Pancrelipase

    a preparation of hog pancreatic enzymes standardized for lipase content.
  • Shwachman-Diamond Syndrome

    an inherited syndrome characterized by exocrine pancreatic insufficiency; hematologic abnormalities (e.g., bone marrow hypoplasia), and skeletal abnormalities (e.g., metaphyseal chondroplasia). germline mutations in the sbds gene are associated with shwachman-diamond syndrome.
  • Necrolytic Migratory Erythema

    recurrent cutaneous manifestation of glucagonoma characterized by necrolytic polycyclic migratory lesions with scaling borders. it is associated with elevated secretion of glucagon by the tumor. other conditions with elevated serum glucagon levels such as hepatic cirrhosis may also result in similar skin lesions, which are referred to as pseudoglucagonoma syndrome.
  • Somatostatinoma

    a somatostatin-secreting tumor derived from the pancreatic delta cells (somatostatin-secreting cells). it is also found in the intestine. somatostatinomas are associated with diabetes mellitus; cholelithiasis; steatorrhea; and hypochlorhydria. the majority of somatostatinomas have the potential for metastasis.
  • Gastrinoma

    a gastrin-secreting neuroendocrine tumor of the non-beta islet cells, the gastrin-secreting cells. this type of tumor is primarily located in the pancreas or the duodenum. majority of gastrinomas are malignant. they metastasize to the liver; lymph nodes; and bone but rarely elsewhere. the presence of gastrinoma is one of three requirements to be met for identification of zollinger-ellison syndrome, which sometimes occurs in families with multiple endocrine neoplasia type 1; (men 1).

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Neoplasm of uncertain behavior of anal canal
  • Neoplasm of uncertain behavior of anal sphincter
  • Neoplasm of uncertain behavior of anus NOS
  • Neoplasm of uncertain behavior of esophagus
  • Neoplasm of uncertain behavior of intestine NOS
  • Neoplasm of uncertain behavior of pancreas

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • neoplasm of uncertain behavior of anal margin D48.5
  • neoplasm of uncertain behavior of anal skin D48.5
  • neoplasm of uncertain behavior of perianal skin D48.5

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert D37.8 to ICD-9-CM

  • ICD-9-CM Code: 235.5 - Unc behav neo GI NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Table of Neoplasms

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »anorectum, anorectal (junction)
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
C21.0C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
    »canal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
    »cloacogenic zone
C21.2C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »anus, anal
    »sphincter
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »canal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »canal
    »anal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »cloacogenic zone
C21.2C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »crypt of Morgagni
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
C15.9C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »abdominal
C15.5C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »cervical
C15.3C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »distal (third)
C15.5C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »lower (third)
C15.5C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »middle (third)
C15.4C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »proximal (third)
C15.3C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »thoracic
C15.4C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »esophagus
    »upper (third)
C15.3C78.89D00.1D13.0D37.8D49.0
»Neoplasm, neoplastic
  »hemorrhoidal zone
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »insular tissue (pancreas)
C25.4C78.89D01.7D13.7D37.8D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
C26.0C78.80D01.40D13.99D37.8D49.0
»Neoplasm, neoplastic
  »intestine, intestinal
    »tract NEC
C26.0C78.89D01.40D13.99D37.8D49.0
»Neoplasm, neoplastic
  »islands or islets of Langerhans
C25.4C78.89D01.7D13.7D37.8D49.0
»Neoplasm, neoplastic
  »junction
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »junction
    »anorectal
C21.8C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »Langerhans, islands or islets
C25.4C78.89D01.7D13.7D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
C25.9C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »body
C25.1C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »duct (of Santorini) (of Wirsung)
C25.3C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »ectopic tissue
C25.7C78.89 D13.6D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »head
C25.0C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »islet cells
C25.4C78.89D01.7D13.7D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »neck
C25.7C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »pancreas
    »tail
C25.2C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »Santorini's duct
C25.3C78.89D01.7D13.6D37.8D49.0
»Neoplasm, neoplastic
  »sphincter
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »sphincter
    »anal
C21.1C78.5D01.3D12.9D37.8D49.0
»Neoplasm, neoplastic
  »spleen, splenic NEC
C26.1C78.89D01.7D13.99D37.8D49.0
»Neoplasm, neoplastic
  »Wirsung's duct
C25.3C78.89D01.7D13.6D37.8D49.0

Patient Education


Digestive Diseases

When you eat, your body breaks food down to a form it can use to build and nourish cells and provide energy. This process is called digestion.

Your digestive system is a series of hollow organs joined in a long, twisting tube. It runs from your mouth to your anus and includes your esophagus, stomach, and small and large intestines. Your liver, gallbladder and pancreas are also involved. They produce juices to help digestion.

There are many types of digestive disorders. The symptoms vary widely depending on the problem. In general, you should see your doctor if you have:

  • Blood in your stool
  • Changes in bowel habits
  • Severe abdominal pain
  • Unintentional weight loss
  • Heartburn not relieved by antacids

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.