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  6. 2024 ICD-10-CM Code D53.1

2024 ICD-10-CM Diagnosis Code D53.1

Other megaloblastic anemias, not elsewhere classified

ICD-10-CM Code:
D53.1
ICD-10 Code for:
Other megaloblastic anemias, not elsewhere classified
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    (D50–D89)
    • Nutritional anemias
      (D50-D53)
      • Other nutritional anemias
        (D53)

D53.1 is a billable diagnosis code used to specify a medical diagnosis of other megaloblastic anemias, not elsewhere classified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acute megaloblastic anemia
  • Acute megaloblastic anemia
  • Acute megaloblastic anemia
  • Acute megaloblastic anemia
  • Acute megaloblastic anemia
  • Acute megaloblastic anemia due to dialysis
  • Acute megaloblastic anemia due to nitrous oxide
  • Acute megaloblastic anemia due to severe illness
  • Acute megaloblastic anemia secondary to total parenteral nutrition
  • Alcohol induced disorder co-occurrent and due to alcohol dependence
  • Anemia due to multiple mechanisms
  • Anemia in mother complicating pregnancy, childbirth AND/OR puerperium
  • Anemia of pregnancy
  • Combined B12 and folate deficiency anemia
  • Combined deficiency anemia
  • Cystic fibrosis with gastritis and megaloblastic anemia syndrome
  • Dimorphic anemia
  • Diphyllobothriasis
  • Helicobacter pylori-associated gastritis
  • Helicobacter-associated gastritis
  • Juvenile type megaloblastic anemia
  • Megaloblastic anemia
  • Megaloblastic anemia due to alcoholism
  • Megaloblastic anemia due to blind loop syndrome
  • Megaloblastic anemia due to celiac disease
  • Megaloblastic anemia due to chronic hemolytic anemia
  • Megaloblastic anemia due to decreased intake of vitamin B>12<
  • Megaloblastic anemia due to dihydrofolate reductase deficiency
  • Megaloblastic anemia due to disease of small intestine
  • Megaloblastic anemia due to disease of small intestine
  • Megaloblastic anemia due to disease of small intestine
  • Megaloblastic anemia due to drugs
  • Megaloblastic anemia due to drugs
  • Megaloblastic anemia due to drugs
  • Megaloblastic anemia due to error of cobalamin metabolism
  • Megaloblastic anemia due to exfoliative dermatitis
  • Megaloblastic anemia due to fish tapeworm
  • Megaloblastic anemia due to gastrectomy
  • Megaloblastic anemia due to hemodialysis
  • Megaloblastic anemia due to hyperalimentation
  • Megaloblastic anemia due to hyperalimentation
  • Megaloblastic anemia due to impaired absorption of folate
  • Megaloblastic anemia due to impaired absorption of folate
  • Megaloblastic anemia due to impaired absorption of folate
  • Megaloblastic anemia due to impaired absorption of folate
  • Megaloblastic anemia due to impaired absorption of folate
  • Megaloblastic anemia due to inborn errors of metabolism
  • Megaloblastic anemia due to inborn errors of metabolism
  • Megaloblastic anemia due to increased requirements
  • Megaloblastic anemia due to pancreatic insufficiency
  • Megaloblastic anemia due to pregnancy
  • Megaloblastic anemia due to tropical sprue
  • Megaloblastic anemia due to vitamin B>12< deficiency
  • Megaloblastic anemia due to Zollinger-Ellison syndrome
  • Megaloblastic anemia, thiamine-responsive, with diabetes mellitus and sensorineural deafness
  • Megaloblastic erythropoiesis
  • Pernicious anemia
  • Refractory megaloblastic anemia
  • Thiamine-responsive megaloblastic anemia
  • Thiamine-responsive megaloblastic anemia

Clinical Classification

Clinical Information

  • Diphyllobothriasis

    infection with tapeworms of the genus diphyllobothrium.

  • Diphyllobothriasis

    an infection that is caused by the tapeworm diphyllobothrium latum and related species; it is transmitted via consumption of raw or undercooked fish, and symptoms include abdominal discomfort, diarrhea, vomiting, fatigue, weight loss, and vitamin b12 deficiency.

  • Arakawa Syndrome II|Arakawa's Syndrome 2|Arakawa's Syndrome II|Homocystinuria-Megaloblastic Anemia, cblG Complementation Type|Methionine Synthase Deficiency|Methylcobalamin Deficiency, cblG Type|Tetrahydrofolate Methyltransferase Deficiency|Tetrahydrofolate Methyltransferase Deficiency

    a rare autosomal dominant inherited metabolic disorder characterized by deficiency of the enzyme tetrahydrofolate-methyltransferase. it results in the abnormal metabolism of methylcobalamin. signs and symptoms include mental retardation, megaloblastic anemia, hypotonia, epilepsy, and hepatosplenomegaly.

  • Homocystinuria-Megaloblastic Anemia, cblE Complementation Type|HMAE|Methylcobalamin Deficiency, cblE Type

    an autosomal recessive condition caused by mutation(s) in the mtrr gene, encoding methionine synthase reductase. it is characterized by homocystinuria and megaloblastic anemia.

  • Megaloblastic Anemia

    anemia characterized by the presence of unusually large erythroblasts in the bone marrow called megaloblasts. it is usually caused by vitamin b12 or folic acid deficiency. other causes include toxins and drugs.

  • Megaloblastic Anemia 1|Imerslund-Gräsbeck Syndrome|Juvenile Megaloblastic Anemia|MGA-1

    an autosomal recessive disorder caused by mutations in the cubn or amn genes. it is characterized by vitamin b12 deficiency due to selective malabsorption of the vitamin, and usually results in megaloblastic anemia appearing in childhood (but not immediately after birth).

  • Other Megaloblastic Anemias, not Elsewhere Classified|Other megaloblastic anemias, not elsewhere classified

    evidence of other megaloblastic anemias, not elsewhere classified not specified elsewhere.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Megaloblastic anemia NOS

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Di Guglielmo's disease C94.0

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert D53.1 to ICD-9-CM

  • ICD-9-CM Code: 281.3 - Megaloblastic anemia NEC

Patient Education


Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include:

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.