ICD-10-CM Tag List · Table of Neoplasms · FY 2026 128 Codes

2026 Uncertain Behavior ICD-10-CM Codes ICD-10-CM

The FY 2026 dataset contains 128 uncertain behavior codes across 12 code blocks. Uncertain behavior codes apply when pathology cannot determine whether a neoplasm is benign or malignant. They come from the Uncertain Behavior column of the Table of Neoplasms. Each code below lists the anatomical sites that map to it.

✓ Built from the official CMS FY 2026 datasetEffective Oct 1, 2025 – Sep 30, 2026
128
Codes
12
Code Blocks
118
Billable
FY 2026
Dataset

Coding Guidance

Uncertain behavior is a pathologist's determination, not a placeholder for missing documentation. When the record simply does not state the behavior, the unspecified behavior codes apply.

ICD-10-CM

All Uncertain Behavior Codes 128 codes · searchable by anatomical site

128 of 128 shown

Neoplasm of uncertain behavior of oral cavity and digestive organs D37 · 17 codes

  • D37.01 Neoplasm of uncertain behavior of lip
  • D37.02 Neoplasm of uncertain behavior of tongue
  • D37.030 Neoplasm of uncertain behavior of the parotid salivary glands
  • D37.031 Neoplasm of uncertain behavior of the sublingual salivary glands
  • D37.032 Neoplasm of uncertain behavior of the submandibular salivary glands
  • D37.039 Neoplasm of uncertain behavior of the major salivary glands, unspecified
  • D37.04 Neoplasm of uncertain behavior of the minor salivary glands
  • D37.05 Neoplasm of uncertain behavior of pharynx
  • D37.09 Neoplasm of uncertain behavior of other specified sites of the oral cavity
  • D37.1 Neoplasm of uncertain behavior of stomach
  • D37.2 Neoplasm of uncertain behavior of small intestine
  • D37.3 Neoplasm of uncertain behavior of appendix
  • D37.4 Neoplasm of uncertain behavior of colon
  • D37.5 Neoplasm of uncertain behavior of rectum
  • D37.6 Neoplasm of uncertain behavior of liver, gallbladder and bile ducts
  • D37.8 Neoplasm of uncertain behavior of other specified digestive organs
  • D37.9 Neoplasm of uncertain behavior of digestive organ, unspecified

Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs D38 · 7 codes

  • D38.0 Neoplasm of uncertain behavior of larynx
  • D38.1 Neoplasm of uncertain behavior of trachea, bronchus and lung
  • D38.2 Neoplasm of uncertain behavior of pleura
  • D38.3 Neoplasm of uncertain behavior of mediastinum
  • D38.4 Neoplasm of uncertain behavior of thymus
  • D38.5 Neoplasm of uncertain behavior of other respiratory organs
  • D38.6 Neoplasm of uncertain behavior of respiratory organ, unspecified

Neoplasm of uncertain behavior of female genital organs D39 · 8 codes

  • D39.0 Neoplasm of uncertain behavior of uterus
  • D39.1 Neoplasm of uncertain behavior of ovaryNon-billable header
  • D39.10 Neoplasm of uncertain behavior of unspecified ovary
  • D39.11 Neoplasm of uncertain behavior of right ovary
  • D39.12 Neoplasm of uncertain behavior of left ovary
  • D39.2 Neoplasm of uncertain behavior of placenta
  • D39.8 Neoplasm of uncertain behavior of other specified female genital organs
  • D39.9 Neoplasm of uncertain behavior of female genital organ, unspecified

Neoplasm of uncertain behavior of male genital organs D40 · 7 codes

  • D40.0 Neoplasm of uncertain behavior of prostate
  • D40.1 Neoplasm of uncertain behavior of testisNon-billable header
  • D40.10 Neoplasm of uncertain behavior of unspecified testis
  • D40.11 Neoplasm of uncertain behavior of right testis
  • D40.12 Neoplasm of uncertain behavior of left testis
  • D40.8 Neoplasm of uncertain behavior of other specified male genital organs
  • D40.9 Neoplasm of uncertain behavior of male genital organ, unspecified

Neoplasm of uncertain behavior of urinary organs D41 · 16 codes

  • D41.0 Neoplasm of uncertain behavior of kidneyNon-billable header
  • D41.00 Neoplasm of uncertain behavior of unspecified kidney
  • D41.01 Neoplasm of uncertain behavior of right kidney
  • D41.02 Neoplasm of uncertain behavior of left kidney
  • D41.1 Neoplasm of uncertain behavior of renal pelvisNon-billable header
  • D41.10 Neoplasm of uncertain behavior of unspecified renal pelvis
  • D41.11 Neoplasm of uncertain behavior of right renal pelvis
  • D41.12 Neoplasm of uncertain behavior of left renal pelvis
  • D41.2 Neoplasm of uncertain behavior of ureterNon-billable header
  • D41.20 Neoplasm of uncertain behavior of unspecified ureter
  • D41.21 Neoplasm of uncertain behavior of right ureter
  • D41.22 Neoplasm of uncertain behavior of left ureter
  • D41.3 Neoplasm of uncertain behavior of urethra
  • D41.4 Neoplasm of uncertain behavior of bladder
  • D41.8 Neoplasm of uncertain behavior of other specified urinary organs
  • D41.9 Neoplasm of uncertain behavior of unspecified urinary organ

Neoplasm of uncertain behavior of meninges D42 · 3 codes

  • D42.0 Neoplasm of uncertain behavior of cerebral meninges
  • D42.1 Neoplasm of uncertain behavior of spinal meninges
  • D42.9 Neoplasm of uncertain behavior of meninges, unspecified

Neoplasm of uncertain behavior of brain and central nervous system D43 · 7 codes

  • D43.0 Neoplasm of uncertain behavior of brain, supratentorial
  • D43.1 Neoplasm of uncertain behavior of brain, infratentorial
  • D43.2 Neoplasm of uncertain behavior of brain, unspecified
  • D43.3 Neoplasm of uncertain behavior of cranial nerves
  • D43.4 Neoplasm of uncertain behavior of spinal cord
  • D43.8 Neoplasm of uncertain behavior of other specified parts of central nervous system
  • D43.9 Neoplasm of uncertain behavior of central nervous system, unspecified

Neoplasm of uncertain behavior of endocrine glands D44 · 12 codes

  • D44.0 Neoplasm of uncertain behavior of thyroid gland
  • D44.1 Neoplasm of uncertain behavior of adrenal glandNon-billable header
  • D44.10 Neoplasm of uncertain behavior of unspecified adrenal gland
  • D44.11 Neoplasm of uncertain behavior of right adrenal gland
  • D44.12 Neoplasm of uncertain behavior of left adrenal gland
  • D44.2 Neoplasm of uncertain behavior of parathyroid gland
  • D44.3 Neoplasm of uncertain behavior of pituitary gland
  • D44.4 Neoplasm of uncertain behavior of craniopharyngeal duct
  • D44.5 Neoplasm of uncertain behavior of pineal gland
  • D44.6 Neoplasm of uncertain behavior of carotid body
  • D44.7 Neoplasm of uncertain behavior of aortic body and other paraganglia
  • D44.9 Neoplasm of uncertain behavior of unspecified endocrine gland

Polycythemia vera D45 · 1 codes

  • D45 Polycythemia vera

Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue D47 · 12 codes

  • D47.0 Mast cell neoplasms of uncertain behaviorNon-billable header
  • D47.01 Cutaneous mastocytosis
  • D47.02 Systemic mastocytosis
  • D47.09 Other mast cell neoplasms of uncertain behavior
  • D47.1 Chronic myeloproliferative disease
  • D47.2 Monoclonal gammopathy
  • D47.3 Essential (hemorrhagic) thrombocythemia
  • D47.4 Osteomyelofibrosis
  • D47.9 Neoplasm of uncertain behavior of lymphoid, hematopoietic and related tissue, unspecified
  • D47.Z1 Post-transplant lymphoproliferative disorder (PTLD)
  • D47.Z2 Castleman disease
  • D47.Z9 Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue

Neoplasm of uncertain behavior of other and unspecified sites D48 · 23 codes

  • D48.0 Neoplasm of uncertain behavior of bone and articular cartilage
  • D48.1 Neoplasm of uncertain behavior of connective and other soft tissueNon-billable header
  • D48.110 Desmoid tumor of head and neck
  • D48.111 Desmoid tumor of chest wall
  • D48.112 Desmoid tumor, intrathoracic
  • D48.113 Desmoid tumor of abdominal wall
  • D48.114 Desmoid tumor, intraabdominal
  • D48.115 Desmoid tumor of upper extremity and shoulder girdle
  • D48.116 Desmoid tumor of lower extremity and pelvic girdle
  • D48.117 Desmoid tumor of back
  • D48.118 Desmoid tumor of other site
  • D48.119 Desmoid tumor of unspecified site
  • D48.19 Other specified neoplasm of uncertain behavior of connective and other soft tissue
  • D48.2 Neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system
  • D48.3 Neoplasm of uncertain behavior of retroperitoneum
  • D48.4 Neoplasm of uncertain behavior of peritoneum
  • D48.5 Neoplasm of uncertain behavior of skin
  • D48.6 Neoplasm of uncertain behavior of breastNon-billable header
  • D48.60 Neoplasm of uncertain behavior of unspecified breast
  • D48.61 Neoplasm of uncertain behavior of right breast
  • D48.62 Neoplasm of uncertain behavior of left breast
  • D48.7 Neoplasm of uncertain behavior of other specified sites
  • D48.9 Neoplasm of uncertain behavior, unspecified

Neoplasms of unspecified behavior D49 · 15 codes

  • D49.0 Neoplasm of unspecified behavior of digestive system
  • D49.1 Neoplasm of unspecified behavior of respiratory system
  • D49.2 Neoplasm of unspecified behavior of bone, soft tissue, and skin
  • D49.3 Neoplasm of unspecified behavior of breast
  • D49.4 Neoplasm of unspecified behavior of bladder
  • D49.5 Neoplasm of unspecified behavior of other genitourinary organsNon-billable header
  • D49.511 Neoplasm of unspecified behavior of right kidney
  • D49.512 Neoplasm of unspecified behavior of left kidney
  • D49.519 Neoplasm of unspecified behavior of unspecified kidney
  • D49.59 Neoplasm of unspecified behavior of other genitourinary organ
  • D49.6 Neoplasm of unspecified behavior of brain
  • D49.7 Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system
  • D49.81 Neoplasm of unspecified behavior of retina and choroid
  • D49.89 Neoplasm of unspecified behavior of other specified sites
  • D49.9 Neoplasm of unspecified behavior of unspecified site

The info icon lists every anatomical site from the table that maps to the code. The filter above searches those anatomical sites too.

Questions About This Page

How do I find the right code for a specific site?

Type the anatomical site into the filter above. Every code on this page carries the site entries that map to it in the Table of Neoplasms. For all six behavior columns side by side, use the Table of Neoplasms.

How is neoplasm behavior determined?

The pathology or clinical documentation names the behavior. When the description of the neoplasm states the behavior, that description overrides the Index guidance, and the matching column of the Table of Neoplasms supplies the code.

How many uncertain behavior codes are there?

The FY 2026 dataset contains 128 uncertain behavior codes across 12 code blocks, 118 of them billable.

Related References

Source: official CMS FY 2026 ICD-10-CM release, effective October 1, 2025 through September 30, 2026.