2026 ICD-10-CM Diagnosis Code D49Neoplasms of unspecified behavior

ICD-10-CM Codes›D50–D89›D49›D49

ICD-10-CM D49
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D49 is a non-billable ICD-10-CM category code for neoplasms of unspecified behavior, so it cannot be submitted on claims. Use a more specific code from this category instead, such as D49.0, D49.1, D49.2, and D49.3.

Code Identity

ICD-10-CM Code
D49
Billable Status
No — Non-Billable Category
Code Describes
Neoplasms of unspecified behavior
Short Description
Neoplasms of unspecified behavior
Same as the full description in the CMS dataset.
Chapter
D49
Neoplasms of unspecified behavior

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD49Neoplasms of unspecified behavior
CategoryD49Neoplasms of unspecified behavior
This CodeD49Neoplasms of unspecified behavior

Specific Coding for Neoplasms of unspecified behaviorOverview

Non-specific codes like D49 require more characters. Use one of these billable codes instead:

  • Use D49.0 for Neoplasm of unspecified behavior of digestive system

  • Use D49.1 for Neoplasm of unspecified behavior of respiratory system

  • Use D49.2 for Neoplasm of unspecified behavior of bone, soft tissue, and skin

  • Use D49.3 for Neoplasm of unspecified behavior of breast

  • Use D49.4 for Neoplasm of unspecified behavior of bladder

  • D49.5 for Neoplasm of unspecified behavior of other genitourinary organs

  • D49.51 for Neoplasm of unspecified behavior of kidney

  • Use D49.59 for Neoplasm of unspecified behavior of other genitourinary organ

  • Use D49.6 for Neoplasm of unspecified behavior of brain

  • Use D49.7 for Neoplasm of unspecified behavior of endocrine glands and other parts of nervous system

  • D49.8 for Neoplasm of unspecified behavior of other specified sites

  • Use D49.81 for Neoplasm of unspecified behavior of retina and choroid

  • Use D49.89 for Neoplasm of unspecified behavior of other specified sites

  • Use D49.9 for Neoplasm of unspecified behavior of unspecified site

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Includes

  • 'growth' NOS
  • neoplasm NOS
  • new growth NOS
  • tumor NOS

Type 1 Excludes

  • neoplasms of uncertain behavior D37 D44 D48

  • Category D49 classifies by site neoplasms of unspecified morphology and behavior. The term 'mass', unless otherwise stated, is not to be regarded as a neoplastic growth.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D49Overview

Is D49 (Neoplasms of unspecified behavior) a billable code?

No. This is a category header that groups the codes for neoplasms of unspecified behavior, and headers cannot be submitted on claims. Claims for neoplasms of unspecified behavior need a more specific code from this category, such as D49.0, D49.1, and D49.2.