Not Valid for Submission
C95.9 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of leukemia, unspecified. The code is not specific and is NOT valid for the year 2021 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Unspecified diagnosis codes like C95.9 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.
Specific Coding for Leukemia, unspecified
Non-specific codes like C95.9 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for leukemia, unspecified:
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code C95.9 are found in the index:
- - Arthritis, arthritic (acute) (chronic) (nonpyogenic) (subacute) - M19.90
- ABELSON MURINE LEUKEMIA VIRUS-. a replication defective strain of murine leukemia virus leukemia virus murine capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukemia after superinfection with friend murine leukemia virus; moloney murine leukemia virus; or rauscher virus.
- ANEMIA REFRACTORY WITH EXCESS OF BLASTS-. chronic refractory anemia with granulocytopenia and/or thrombocytopenia. myeloblasts and progranulocytes constitute 5 to 40 percent of the nucleated marrow cells.
- LEUKEMIA VIRUS BOVINE-. the type species of deltaretrovirus that causes a form of bovine lymphosarcoma enzootic bovine leukosis or persistent lymphocytosis.
- BURKITT LYMPHOMA-. a form of undifferentiated malignant lymphoma usually found in central africa but also reported in other parts of the world. it is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. b cell antigens are expressed on the immature cells that make up the tumor in virtually all cases of burkitt lymphoma. the epstein barr virus herpesvirus 4 human has been isolated from burkitt lymphoma cases in africa and it is implicated as the causative agent in these cases; however most non african cases are ebv negative.
- LEUKEMIA ERYTHROBLASTIC ACUTE-. a myeloproliferative disorder characterized by neoplastic proliferation of erythroblastic and myeloblastic elements with atypical erythroblasts and myeloblasts in the peripheral blood.
- LEUKEMIA VIRUS FELINE-. a species of gammaretrovirus causing leukemia lymphosarcoma immune deficiency or other degenerative diseases in cats. several cellular oncogenes confer on felv the ability to induce sarcomas see also sarcoma viruses feline.
- LEUKEMIA-. a progressive malignant disease of the blood forming organs characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. from the merck manual 2006
- LEUKEMIA L1210-. an experimental lymphocytic leukemia of mice.
- LEUKEMIA L5178-. an experimental lymphocytic leukemia of mice.
- LEUKEMIA P388-. an experimental lymphocytic leukemia originally induced in dba/2 mice by painting with methylcholanthrene.
- LEUKEMIA EXPERIMENTAL-. leukemia induced experimentally in animals by exposure to leukemogenic agents such as viruses; radiation; or by transplantation of leukemic tissues.
- LEUKEMIA HAIRY CELL-. a neoplastic disease of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset splenomegaly anemia granulocytopenia thrombocytopenia little or no lymphadenopathy and the presence of "hairy" or "flagellated" cells in the blood and bone marrow.
- LEUKEMIA LYMPHOID-. leukemia associated with hyperplasia of the lymphoid tissues and increased numbers of circulating malignant lymphocytes and lymphoblasts.
- LEUKEMIA MAST CELL-. a form of systemic mastocytosis mastocytosis systemic characterized by the presence of large numbers of tissue mast cells in the peripheral blood without skin lesions. it is a high grade leukemia disease with bone marrow smear of >20% mast cells multi organ failure and a short survival.
- LEUKEMIA MEGAKARYOBLASTIC ACUTE-. an acute myeloid leukemia in which 20 30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. myelofibrosis or increased bone marrow reticulin is common.
- LEUKEMIA MONOCYTIC ACUTE-. an acute myeloid leukemia in which 80% or more of the leukemic cells are of monocytic lineage including monoblasts promonocytes and monocytes.
- LEUKEMIA MYELOID-. form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors myeloid progenitor cells in the bone marrow and other sites.
- LEUKEMIA PLASMA CELL-. a rare aggressive variant of multiple myeloma characterized by the circulation of excessive plasma cells in the peripheral blood. it can be a primary manifestation of multiple myeloma or develop as a terminal complication during the disease.
- LEUKEMIA RADIATION INDUCED-. leukemia produced by exposure to ionizing radiation or non ionizing radiation.
- MOLONEY MURINE LEUKEMIA VIRUS-. a strain of murine leukemia virus leukemia virus murine arising during the propagation of s37 mouse sarcoma and causing lymphoid leukemia in mice. it also infects rats and newborn hamsters. it is apparently transmitted to embryos in utero and to newborns through mother's milk.
- LEUKEMIA VIRUS MURINE-. species of gammaretrovirus containing many well defined strains producing leukemia in mice. disease is commonly induced by injecting filtrates of propagable tumors into newborn mice.
- RAUSCHER VIRUS-. a strain of murine leukemia virus associated with mouse tumors similar to those caused by the friend murine leukemia virus. it is a replication competent murine leukemia virus. it can act as a helper virus when complexing with a defective transforming component rauscher spleen focus forming virus.
- HUMAN T LYMPHOTROPIC VIRUS 2-. a strain of primate t lymphotropic virus 2 that can transform normal t lymphocytes and can replicate in both t and b cell lines. the virus is related to but distinct from htlv 1.
- HUMAN T LYMPHOTROPIC VIRUS 1-. a strain of primate t lymphotropic virus 1 isolated from mature t4 cells in patients with t lymphoproliferation malignancies. it causes adult t cell leukemia leukemia lymphoma t cell acute htlv i associated t cell lymphoma lymphoma t cell and is involved in mycosis fungoides sezary syndrome and tropical spastic paraparesis paraparesis tropical spastic.
- LEUKEMIA B CELL-. a malignant disease of the b lymphocytes in the bone marrow and/or blood.
- LEUKEMIA LYMPHOCYTIC CHRONIC B CELL-. a chronic leukemia characterized by abnormal b lymphocytes and often generalized lymphadenopathy. in patients presenting predominately with blood and bone marrow involvement it is called chronic lymphocytic leukemia cll; in those predominately with enlarged lymph nodes it is called small lymphocytic lymphoma. these terms represent spectrums of the same disease.
- PRECURSOR B CELL LYMPHOBLASTIC LEUKEMIA LYMPHOMA-. a leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. frequent sites involve lymph nodes skin and bones. it most commonly presents as leukemia.
- LEUKEMIA BIPHENOTYPIC ACUTE-. an acute leukemia exhibiting cell features characteristic of both the myeloid and lymphoid lineages and probably arising from multipotent stem cells.
- LEUKEMIA T CELL-. a malignant disease of the t lymphocytes in the bone marrow thymus and/or blood.
- LEUKEMIA LYMPHOMA ADULT T CELL-. aggressive t cell malignancy with adult onset caused by human t lymphotropic virus 1. it is endemic in japan the caribbean basin southeastern united states hawaii and parts of central and south america and sub saharan africa.
- LEUKEMIA PROLYMPHOCYTIC T CELL-. a lymphoid leukemia characterized by a profound lymphocytosis with or without lymphadenopathy hepatosplenomegaly frequently rapid progression and short survival. it was formerly called t cell chronic lymphocytic leukemia.
- LEUKEMIA PROLYMPHOCYTIC-. a chronic leukemia characterized by a large number of circulating prolymphocytes. it can arise spontaneously or as a consequence of transformation of chronic lymphocytic leukemia.
- LEUKEMIA MYELOGENOUS CHRONIC BCR ABL POSITIVE-. clonal hematopoetic disorder caused by an acquired genetic defect in pluripotent stem cells. it starts in myeloid cells of the bone marrow invades the blood and then other organs. the condition progresses from a stable more indolent chronic phase leukemia myeloid chronic phase lasting up to 7 years to an advanced phase composed of an accelerated phase leukemia myeloid accelerated phase and blast crisis.
- LEUKEMIA MYELOID ACCELERATED PHASE-. the phase of chronic myeloid leukemia following the chronic phase leukemia myeloid chronic phase where there are increased systemic symptoms worsening cytopenias and refractory leukocytosis.
- LEUKEMIA MYELOID CHRONIC PHASE-. the initial phase of chronic myeloid leukemia consisting of an relatively indolent period lasting from 4 to 7 years. patients range from asymptomatic to those exhibiting anemia; splenomegaly; and increased cell turnover. there are 5% or fewer blast cells in the blood and bone marrow in this phase.
- LEUKEMIA NEUTROPHILIC CHRONIC-. a rare myeloproliferative disorder that is characterized by a sustained mature neutrophilic leukocytosis. no monocytosis eosinophilia or basophilia is present nor is there a philadelphia chromosome or bcr abl fusion gene genes abl.
- LEUKEMIA MYELOID ACUTE-. clonal expansion of myeloid blasts in bone marrow blood and other tissue. myeloid leukemias develop from changes in cells that normally produce neutrophils; basophils; eosinophils; and monocytes.
- LEUKEMIA BASOPHILIC ACUTE-. a rare acute myeloid leukemia in which the primary differentiation is to basophils. it is characterized by an extreme increase of immature basophilic granulated cells in the bone marrow and blood. mature basophils are usually sparse.
- LEUKEMIA EOSINOPHILIC ACUTE-. a rare acute myeloid leukemia characterized by abnormal eosinophils in the bone marrow.
- LEUKEMIA PROMYELOCYTIC ACUTE-. an acute myeloid leukemia in which abnormal promyelocytes predominate. it is frequently associated with disseminated intravascular coagulation.
- LEUKEMIA MYELOMONOCYTIC CHRONIC-. a myelodysplastic myeloproliferative disease characterized by monocytosis increased monocytes in the bone marrow variable degrees of dysplasia but an absence of immature granulocytes in the blood.
- LEUKEMIA MYELOMONOCYTIC ACUTE-. a pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. at least 20% of non erythroid cells are of monocytic origin.
- DELTARETROVIRUS ANTIBODIES-. antibodies reactive with various types of human t cell leukemia/lymphoma antigens or bovine leukemia virus antigens.
- HTLV I ANTIBODIES-. antibodies reactive with the htlv i antigens.
- HTLV II ANTIBODIES-. antibodies reactive with the htlv ii antigens.
- DELTARETROVIRUS ANTIGENS-. antigens associated with the deltaretrovirus; htlv i antigens and htlv ii antigens belong to this group.
- HTLV I ANTIGENS-. antigens associated with human t lymphotropic virus 1.
- HTLV II ANTIGENS-. antigens associated with human t lymphotropic virus 2.
- LEUKEMIA FELINE-. a neoplastic disease of cats frequently associated with feline leukemia virus infection.
- ENZOOTIC BOVINE LEUKOSIS-. a lymphoid neoplastic disease in cattle caused by the bovine leukemia virus. enzootic bovine leukosis may take the form of lymphosarcoma malignant lymphoma or leukemia but the presence of malignant cells in the blood is not a consistent finding.
- RADIATION LEUKEMIA VIRUS-. a strain of murine leukemia virus leukemia virus murine isolated from radiation induced lymphomas in c57bl mice. it is leukemogenic thymotrophic can be transmitted vertically and replicates only in vivo.
- HYPEREOSINOPHILIC SYNDROME-. a heterogeneous group of disorders with the common feature of prolonged eosinophilia of unknown cause and associated organ system dysfunction including the heart central nervous system kidneys lungs gastrointestinal tract and skin. there is a massive increase in the number of eosinophils in the blood mimicking leukemia and extensive eosinophilic infiltration of the various organs.
- DELTARETROVIRUS-. a genus in the family retroviridae consisting of exogenous horizontally transmitted viruses found in a few groups of mammals. infections caused by these viruses include human b or adult t cell leukemia/lymphoma leukemia lymphoma t cell acute htlv i associated and bovine leukemia enzootic bovine leukosis. the type species is leukemia virus bovine.
- LEUKEMIA VIRUS GIBBON APE-. a species of gammaretrovirus causing leukemia in the gibbon ape. natural transmission is by contact.
- STATHMIN-. a ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of signal transduction pathways. phosphorylation of stathmin occurs during cell cycle progression and stathmin functions as a microtubule destabilizing protein that promotes microtubule depolymerization during interphase and late mitosis. stathmin is expressed at very high levels in a variety of human cancers.
- LEUKEMIA INHIBITORY FACTOR-. an interleukin 6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation differentiation and survival. leukemia inhibitory factor binds to and acts through the lif receptor.
- RECEPTORS OSM LIF-. cell surface receptors formed from the dimerization of lif receptor alpha subunit with cytokine receptor gp130. although originally described as receptors for leukemia inhibitory factor these receptors also bind the closely related protein oncostatin m and are referred to as both lif receptors and type i oncostatin m receptors.
- LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT-. a receptor subunit that combines with cytokine receptor gp130 to form the dual specificity receptor for leukemia inhibitory factor and oncostatin m. the subunit is also a component of the ciliary neurotrophic factor receptor. both membrane bound and secreted isoforms of the receptor subunit exist due to alternative splicing of its mrna. the secreted isoform is believed to act as an inhibitory receptor while the membrane bound form is a signaling receptor.
- LEUKEMIA LARGE GRANULAR LYMPHOCYTIC-. a spectrum of disorders characterized by clonal expansions of the peripheral blood lymphocyte populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. subtypes develop from either cd3 negative natural killer cells or cd3 positive t cells. the clinical course of both subtypes can vary from spontaneous regression to progressive malignant disease.
- PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA LYMPHOMA-. a neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. it is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
- PRECURSOR T CELL LYMPHOBLASTIC LEUKEMIA LYMPHOMA-. a leukemia/lymphoma found predominately in children and young adults and characterized lymphadenopathy and thymus gland involvement. it most frequently presents as a lymphoma but a leukemic progression in the bone marrow is common.
- LEUKEMIA PROLYMPHOCYTIC B CELL-. a neoplasm of prolymphocytes affecting the blood bone marrow and spleen. it is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.
- LEUKEMIA MYELOMONOCYTIC JUVENILE-. a leukemia affecting young children characterized by splenomegaly enlarged lymph nodes rashes and hemorrhages. traditionally classed as a myeloproliferative disease it is now considered a mixed myeloproliferative mylelodysplastic disorder.
- LEUKEMIA MYELOID CHRONIC ATYPICAL BCR ABL NEGATIVE-. a myelodysplastic/myeloproliferative disorder characterized by myelodysplasia associated with bone marrow and peripheral blood patterns similar to chronic myeloid leukemia but cytogenetically lacking a philadelphia chromosome or bcr/abl fusion gene genes abl.
- TETRASPANIN 29-. a subtype of tetraspanin protein that plays a role in cell adhesion cell motility and tumor metastasis. it functions in platelet activation and aggregation the formation of paranodal junctions in neuronal tissue and the fusion of sperm with egg.
Information for Patients
Leukemia is cancer of the white blood cells. White blood cells help your body fight infection. Your blood cells form in your bone marrow. In leukemia, the bone marrow produces abnormal white blood cells. These cells crowd out the healthy blood cells, making it hard for blood to do its work.
There are different types of leukemia, including
- Acute lymphocytic leukemia
- Acute myeloid leukemia
- Chronic lymphocytic leukemia
- Chronic myeloid leukemia
Leukemia can develop quickly or slowly. Chronic leukemia grows slowly. In acute leukemia, the cells are very abnormal and their number increases rapidly. Adults can get either type; children with leukemia most often have an acute type.Some leukemias can often be cured. Other types are hard to cure, but you can often control them. Treatments may include chemotherapy, radiation and stem cell transplantation. Even if symptoms disappear, you might need therapy to prevent a relapse.
NIH: National Cancer Institute
- B-cell leukemia/lymphoma panel (Medical Encyclopedia)
- Bone marrow transplant (Medical Encyclopedia)
- Hairy cell leukemia (Medical Encyclopedia)
- Leukemia (Medical Encyclopedia)
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