2024 ICD-10-CM Diagnosis Code D01.5

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Biliary intraepithelial neoplasia grade 3 of liver
• Carcinoma in situ of ampulla of Vater
• Carcinoma in situ of biliary tract
• Carcinoma in situ of common bile duct
• Carcinoma in situ of common hepatic duct
• Carcinoma in situ of cystic duct
• Carcinoma in situ of duodenum
• Carcinoma in situ of duodenum
• Carcinoma in situ of extrahepatic bile ducts
• Carcinoma in situ of gallbladder
• Carcinoma in situ of hepatic duct
• Carcinoma in situ of intrahepatic bile ducts
• Carcinoma in situ of liver
• Carcinoma in situ of liver and/or biliary system
• Carcinoma in situ of pancreas
• Carcinoma in situ of pancreas
• Carcinoma in situ of pancreatic duct
• Carcinoma in situ of pancreatic duct
• Carcinoma in situ of small intestine
• Carcinoma in situ of small intestine
• Carcinoma in situ of sphincter of Oddi
• High grade flat intraepithelial neoplasia of ampulla of Vater
• High grade flat intraepithelial neoplasia of biliary duct
• High grade flat intraepithelial neoplasia of gallbladder
• High grade glandular intraepithelial neoplasia of duodenum
• High grade glandular intraepithelial neoplasia of small intestine
• Intraductal papillary neoplasia with high grade intraepithelial neoplasia of liver
• Neoplasm of cystic duct

Clinical Information

• Ampulla of Vater

  a dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct, also known as the hepatopancreatic ampulla.

• Acalculous Cholecystitis

  inflammation of the gallbladder wall in the absence of gallstones.

• Biliary Dyskinesia

  a motility disorder characterized by biliary colic, absence of gallstones, and an abnormal gallbladder ejection fraction. it is caused by gallbladder dyskinesia and/or sphincter of oddi dysfunction.

• Cholecystitis

  inflammation of the gallbladder; generally caused by impairment of bile flow, gallstones in the biliary tract, infections, or other diseases.

• Gallbladder

  a storage reservoir for bile secretion. gallbladder allows the delivery of bile acids at a high concentration and in a controlled manner, via the cystic duct to the duodenum, for degradation of dietary lipid.

• Gallbladder Diseases

  diseases of the gallbladder. they generally involve the impairment of bile flow, gallstones in the biliary tract, infections, neoplasms, or other diseases.

• Gallbladder Emptying

  a process whereby bile is delivered from the gallbladder into the duodenum. the emptying is caused by both contraction of the gallbladder and relaxation of the sphincter mechanism at the choledochal terminus.

• Gallbladder Neoplasms

  tumors or cancer of the gallbladder.

• Hep G2 Cells

  a human liver tumor cell line used to study a variety of liver-specific metabolic functions.

• Hepatoblastoma

  a malignant neoplasm occurring in young children, primarily in the liver, composed of tissue resembling embryonal or fetal hepatic epithelium, or mixed epithelial and mesenchymal tissues. (stedman, 25th ed)

D01.5 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

MS-DRG	MS-DRG Title	MCD	Relative Weight
435	MALIGNANCY OF HEPATOBILIARY SYSTEM OR PANCREAS WITH MCC	07	1.7599
436	MALIGNANCY OF HEPATOBILIARY SYSTEM OR PANCREAS WITH CC	07	1.1007
437	MALIGNANCY OF HEPATOBILIARY SYSTEM OR PANCREAS WITHOUT CC/MCC	07	0.8311

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Convert D01.5 to ICD-9-CM

• ICD-9-CM Code: 230.8 - Ca in situ liver/biliary

Table of Neoplasms

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Filter table of neoplasms:

Neoplasm, neoplastic	Malignant Primary	Malignant Secondary	CaInSitu	Benign	Uncertain Behavior	Unspecified Behavior
»Neoplasm, neoplastic   »ampulla of Vater	C24.1	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)	C24.9	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)     »canaliculi (biliferi) (intrahepatic)	C22.1	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)     »canals, interlobular	C22.1	C78.89	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)     »duct or passage (common) (cystic) (extrahepatic)	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)     »duct or passage (common) (cystic) (extrahepatic)       »interlobular	C22.1	C78.89	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)     »duct or passage (common) (cystic) (extrahepatic)       »intrahepatic	C22.1	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »bile or biliary (tract)     »duct or passage (common) (cystic) (extrahepatic)       »intrahepatic         »and extrahepatic	C24.8	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »canaliculi, biliary (biliferi) (intrahepatic)	C22.1	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »cholangiole	C22.1	C78.89	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »choledochal duct	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »common (bile) duct	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »cystic (bile) duct (common)	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »extrahepatic (bile) duct	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »gall duct (extrahepatic)	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »gall duct (extrahepatic)     »intrahepatic	C22.1	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »gallbladder	C23	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »hepatic [See Also: Index to disease, by histology]	C22.9	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »hepatic [See Also: Index to disease, by histology]     »duct (bile)	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »hepatic [See Also: Index to disease, by histology]     »primary	C22.8	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »hepatobiliary	C24.9	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »hepatoblastoma	C22.2	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »hepatoma	C22.0	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »intrahepatic (bile) duct	C22.1	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »liver [See Also: Index to disease, by histology]	C22.9	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »liver [See Also: Index to disease, by histology]     »primary	C22.8	C78.7	D01.5	D13.4	D37.6	D49.0
»Neoplasm, neoplastic   »sphincter     »of Oddi	C24.0	C78.89	D01.5	D13.5	D37.6	D49.0
»Neoplasm, neoplastic   »Vater's ampulla	C24.1	C78.89	D01.5	D13.5	D37.6	D49.0

Patient Education

Bile Duct Cancer

Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes.

Bile duct cancer is rare. It can happen in the parts of the bile ducts that are outside or inside the liver. Cancer of the bile duct outside of the liver is much more common. Risk factors include having inflammation of the bile duct, ulcerative colitis, and some liver diseases.

Symptoms can include:

• Jaundice
• Itchy skin
• Fever
• Abdominal pain

Tests to diagnose bile duct cancer may include a physical exam, imaging tests of the liver and bile ducts, blood tests, and a biopsy.

Treatments include surgery, radiation therapy, and chemotherapy.

NIH: National Cancer Institute

[Learn More in MedlinePlus]

Gallbladder Cancer

Your gallbladder is a pear-shaped organ under your liver. It stores bile, a fluid made by your liver to digest fat. As your stomach and intestines digest food, your gallbladder releases bile through a tube called the common bile duct. The duct connects your gallbladder and liver to your small intestine.

Cancer of the gallbladder is rare. It is more common in women and Native Americans. Symptoms include

• Jaundice (yellowing of the skin and whites of the eyes)
• Pain above the stomach
• Fever
• Nausea and vomiting
• Bloating
• Lumps in the abdomen

It is hard to diagnose gallbladder cancer in its early stages. Sometimes doctors find it when they remove the gallbladder for another reason. But people with gallstones rarely have gallbladder cancer. Because it is often found late, it can be hard to treat gallbladder cancer. Treatment options include surgery, chemotherapy, radiation, or a combination.

NIH: National Cancer Institute

[Learn More in MedlinePlus]

Liver Cancer

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons. Primary liver cancer starts in the liver. Metastatic liver cancer starts somewhere else and spreads to your liver.

Risk factors for primary liver cancer include :

• Having hepatitis B or C
• Heavy alcohol use
• Having cirrhosis, or scarring of the liver
• Having hemochromatosis, an iron storage disease
• Obesity and diabetes

Symptoms can include a lump or pain on the right side of your abdomen and yellowing of the skin. However, you may not have symptoms until the cancer is advanced. This makes it harder to treat. Doctors use tests that examine the liver and the blood to diagnose liver cancer. Treatment options include surgery, radiation, chemotherapy, or liver transplantation.

NIH: National Cancer Institute

[Learn More in MedlinePlus]

What is Bile Duct Cancer (Cholangiocarcinoma)?

Learn about bile duct cancer (cholangiocarcinoma) risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.