2026 ICD-10-CM Diagnosis Code C22Malignant neoplasm of liver and intrahepatic bile ducts

ICD-10-CM Codes›C00–D49›C15-C26›C22

ICD-10-CM C22
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C22 is a non-billable ICD-10-CM category code for malignant neoplasm of liver and intrahepatic bile ducts, so it cannot be submitted on claims. Use a more specific code from this category instead, such as C22.0, C22.1, C22.2, and C22.3.

Code Identity

ICD-10-CM Code
C22
Billable Status
No — Non-Billable Category
Code Describes
Malignant neoplasm of liver and intrahepatic bile ducts
Chapter
C15-C26
Malignant neoplasms of digestive organs

Code Classification

ChapterC00–D49Neoplasms
SectionC15-C26Malignant neoplasms of digestive organs
CategoryC22Malignant neoplasm of liver and intrahepatic bile ducts
This CodeC22Malignant neoplasm of liver and intrahepatic bile ducts

Specific Coding for Malignant neoplasm of liver and intrahepatic bile ductsOverview

Non-specific codes like C22 require more characters. Use one of these billable codes instead:

  • Use C22.0 for Liver cell carcinoma

  • Use C22.1 for Intrahepatic bile duct carcinoma

  • Use C22.2 for Hepatoblastoma

  • Use C22.3 for Angiosarcoma of liver

  • Use C22.4 for Other sarcomas of liver

  • Use C22.7 for Other specified carcinomas of liver

  • Use C22.8 for Malignant neoplasm of liver, primary, unspecified as to type

  • Use C22.9 for Malignant neoplasm of liver, not specified as primary or secondary

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Use Additional Code

Type 1 Excludes

  • malignant neoplasm of biliary tract NOS C24.9
  • secondary malignant neoplasm of liver and intrahepatic bile duct C78.7

Patient EducationClinical

Bile Duct Cancer

Your liver makes a digestive juice called bile. Your gallbladder stores it between meals. When you eat, your gallbladder pushes the bile into tubes called bile ducts. They carry the bile to your small intestine. The bile helps break down fat. It also helps the liver get rid of toxins and wastes.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C22Overview

Is C22 (Malignant neoplasm of liver and intrahepatic bile ducts) a billable code?

No. This is a category header that groups the codes for malignant neoplasm of liver and intrahepatic bile ducts, and headers cannot be submitted on claims. Claims for malignant neoplasm of liver and intrahepatic bile ducts need a more specific code from this category, such as C22.0, C22.1, and C22.2.