ICD-10-CM Code D48.1

Neoplasm of uncertain behavior of connective and other soft tissue

Version 2020 Billable Code Neoplasm Uncertain Behavior

Valid for Submission

D48.1 is a billable code used to specify a medical diagnosis of neoplasm of uncertain behavior of connective and other soft tissue. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D48.1 might also be used to specify conditions or terms like aggressive angiomyxoma, aggressive fibromatosis, alport syndrome, alport syndrome x-linked, angiomyxoma, atypical fibrous histiocytoma of soft tissue, etc

The following anatomical sites found in the Table of Neoplasms apply to this code given the correct histological behavior: abdomen, abdominal wall [See Also: Neoplasm, abdomen, wall, skin] connective tissue ; adipose tissue [See Also: Neoplasm, connective tissue] ; aorta (thoracic) ; aorta (thoracic) abdominal ; aponeurosis ; aponeurosis palmar ; aponeurosis plantar ; etc

ICD-10:D48.1
Short Description:Neoplasm of uncertain behavior of connctv/soft tiss
Long Description:Neoplasm of uncertain behavior of connective and other soft tissue

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D48.1:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Neoplasm of uncertain behavior of connective tissue of ear
  • Neoplasm of uncertain behavior of connective tissue of eyelid
  • Stromal tumors of uncertain behavior of digestive system

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • neoplasm of uncertain behavior of articular cartilage D48.0
  • neoplasm of uncertain behavior of cartilage of larynx D38.0
  • neoplasm of uncertain behavior of cartilage of nose D38.5
  • neoplasm of uncertain behavior of connective tissue of breast D48.6

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D48.1 are found in the index:


Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Aggressive angiomyxoma
  • Aggressive fibromatosis
  • Alport syndrome
  • Alport syndrome X-linked
  • Angiomyxoma
  • Atypical fibrous histiocytoma of soft tissue
  • Atypical fibrous histiocytoma of soft tissue
  • Atypical fibroxanthoma - spindle cell type
  • Atypical fibroxanthoma of skin
  • Atypical lipoma of soft tissue
  • Chondromatosis
  • Chondromatosis of synovium of hip joint
  • Chondromatosis of synovium of knee joint
  • Chondromatosis of synovium of temporomandibular joint
  • Composite hemangioendothelioma
  • Congenital nephritis
  • Desmoplastic fibroma of lower limb
  • Epithelioid hemangioendothelioma
  • Extragastrointestinal stromal tumor of peritoneum
  • Giant cell tumor of synovium and/or tendon sheath
  • Hemangiopericytoma
  • Kaposiform hemangioendothelioma
  • Lymphangiomyomatosis of connective tissue
  • Myxoma
  • Neoplasm of coccygeal body
  • Neoplasm of diaphragm
  • Neoplasm of great vessels
  • Neoplasm of muscle of buttock
  • Neoplasm of muscle of face
  • Neoplasm of muscle of hip
  • Neoplasm of muscle of hip
  • Neoplasm of muscle of inguinal region
  • Neoplasm of muscle of neck
  • Neoplasm of muscle of pelvis
  • Neoplasm of muscle of pelvis
  • Neoplasm of muscle of perineum
  • Neoplasm of muscle of shoulder
  • Neoplasm of muscle of thorax
  • Neoplasm of muscle of thorax
  • Neoplasm of muscle of upper limb
  • Neoplasm of muscle of upper limb
  • Neoplasm of soft tissues of hip
  • Neoplasm of soft tissues of inguinal region
  • Neoplasm of soft tissues of shoulder
  • Neoplasm of uncertain behavior of axilla
  • Neoplasm of uncertain behavior of blood vessel
  • Neoplasm of uncertain behavior of coccygeal body
  • Neoplasm of uncertain behavior of connective and soft tissue
  • Neoplasm of uncertain behavior of diaphragm
  • Neoplasm of uncertain behavior of great vessels
  • Neoplasm of uncertain behavior of inguinal region
  • Neoplasm of uncertain behavior of inguinal region
  • Neoplasm of uncertain behavior of muscle
  • Neoplasm of uncertain behavior of muscle of abdomen
  • Neoplasm of uncertain behavior of muscle of buttock
  • Neoplasm of uncertain behavior of muscle of face
  • Neoplasm of uncertain behavior of muscle of head
  • Neoplasm of uncertain behavior of muscle of hip
  • Neoplasm of uncertain behavior of muscle of inguinal region
  • Neoplasm of uncertain behavior of muscle of lower limb
  • Neoplasm of uncertain behavior of muscle of neck
  • Neoplasm of uncertain behavior of muscle of pelvis
  • Neoplasm of uncertain behavior of muscle of perineum
  • Neoplasm of uncertain behavior of muscle of shoulder
  • Neoplasm of uncertain behavior of muscle of thorax
  • Neoplasm of uncertain behavior of muscle of trunk
  • Neoplasm of uncertain behavior of muscle of upper limb
  • Neoplasm of uncertain behavior of paraganglia
  • Neoplasm of uncertain behavior of shoulder
  • Neoplasm of uncertain behavior of shoulder
  • Neoplasm of uncertain behavior of soft tissue of hand
  • Neoplasm of uncertain behavior of soft tissues
  • Neoplasm of uncertain behavior of soft tissues of abdomen
  • Neoplasm of uncertain behavior of soft tissues of axilla
  • Neoplasm of uncertain behavior of soft tissues of buttock
  • Neoplasm of uncertain behavior of soft tissues of face
  • Neoplasm of uncertain behavior of soft tissues of head
  • Neoplasm of uncertain behavior of soft tissues of hip
  • Neoplasm of uncertain behavior of soft tissues of inguinal region
  • Neoplasm of uncertain behavior of soft tissues of lower limb
  • Neoplasm of uncertain behavior of soft tissues of neck
  • Neoplasm of uncertain behavior of soft tissues of pelvis
  • Neoplasm of uncertain behavior of soft tissues of perineum
  • Neoplasm of uncertain behavior of soft tissues of shoulder
  • Neoplasm of uncertain behavior of soft tissues of thorax
  • Neoplasm of uncertain behavior of soft tissues of trunk
  • Neoplasm of uncertain behavior of soft tissues of upper limb
  • Periosteal desmoid
  • Pleomorphic hyalinizing angiectatic tumor of soft tissue
  • Reactive fibrous tissue proliferation
  • Retiform hemangioendothelioma
  • Superficial angiomyxoma
  • Synovial chondromatosis
  • X-linked diffuse leiomyomatosis with Alport syndrome

Diagnostic Related Groups

The ICD-10 code D48.1 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.

  • 564 - OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH MCC
  • 565 - OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH CC
  • 566 - OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITHOUT CC/MCC

Convert D48.1 to ICD-9

  • 238.1 - Unc behav neo soft tissu (Approximate Flag)

Code Classification

  • Neoplasms (C00–D48)
    • Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
      • Neoplasm of uncertain behavior of other and unsp sites (D48)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Table of Neoplasms

The code D48.1 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»abdomen, abdominal
  »wall [See Also: Neoplasm, abdomen, wall, skin]
    »connective tissue
C49.4C79.8D21.4D48.1D49.2
»adipose tissue [See Also: Neoplasm, connective tissue]
C49.4C79.89D21.9D48.1D49.2
»aorta (thoracic)
C49.3C79.89D21.3D48.1D49.2
»aorta (thoracic)
  »abdominal
C49.4C79.89D21.4D48.1D49.2
»aponeurosis
C49.9C79.89D21.9D48.1D49.2
»aponeurosis
  »palmar
C49.1C79.89D21.1D48.1D49.2
»aponeurosis
  »plantar
C49.2C79.89D21.2D48.1D49.2
»carotid (artery)
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »auricular
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »ear (external)
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »eyelid
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »pinna
C49.0C79.89D21.0D48.1D49.2
»coccygeal
C49.5C79.89D21.5D48.1D49.2
»coccygeal
  »body or glomus
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »abdomen
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »abdominal wall
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »ankle
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »antecubital fossa or space
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »arm
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »auricle (ear)
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »axilla
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »back
C49.6C79.89D21.6D48.1D49.2
»connective tissue NEC
  »buttock
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »calf
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »cervical region
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »cheek
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »chest (wall)
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »chin
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »diaphragm
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »ear (external)
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »elbow
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »extrarectal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »extremity
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »extremity
    »lower
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »extremity
    »upper
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »eyelid
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »face
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »finger
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »flank
C49.6C79.89D21.6D48.1D49.2
»connective tissue NEC
  »foot
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »forearm
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »forehead
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »gastric
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »gastrointestinal
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »gluteal region
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »great vessels NEC
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »groin
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »hand
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »head
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »heel
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »hip
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »hypochondrium
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »iliopsoas muscle
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »infraclavicular region
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »inguinal (canal) (region)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »intestinal
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »intrathoracic
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »ischiorectal fossa
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »jaw
C03.9C79.89D00.03D10.39D48.1D49.0
»connective tissue NEC
  »knee
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »leg
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »limb NEC
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »limb NEC
    »lower
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »limb NEC
    »upper
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »nates
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »neck
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »orbit
C69.6C79.49D09.2D31.6D48.1D49.89
»connective tissue NEC
  »pararectal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »para-urethral
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »paravaginal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »pelvis (floor)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »pelvo-abdominal
C49.8C79.89D21.6D48.1D49.2
»connective tissue NEC
  »perineum
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »perirectal (tissue)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »periurethral (tissue)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »popliteal fossa or space
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »presacral
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »psoas muscle
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »pterygoid fossa
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »rectovaginal septum or wall
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »rectovesical
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »sacrococcygeal region
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »scalp
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »scapular region
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »shoulder
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »stomach
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »submental
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »supraclavicular region
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »temple
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »temporal region
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »thigh
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »thoracic (duct) (wall)
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »thorax
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »thumb
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »toe
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »trunk
C49.6C79.89D21.6D48.1D49.2
»connective tissue NEC
  »umbilicus
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »vesicorectal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »wrist
C49.1C79.89D21.1D48.1D49.2
»diaphragm
C49.3C79.89D21.3D48.1D49.2
»ear (external) [See Also: Neoplasm, skin, ear]
  »cartilage
C49.0C79.89D21.0D48.1D49.2
»eyelid (lower) (skin) (upper)
  »cartilage
C49.0C79.89D21.0D48.1D49.2
»fascia [See Also: Neoplasm, connective tissue]
C49.1C79.89D21.1D48.1D49.2
»fascia [See Also: Neoplasm, connective tissue]
  »palmar
C49.1C79.89D21.1D48.1D49.2
»fascia [See Also: Neoplasm, connective tissue]
  »plantar
C49.2C79.89D21.2D48.1D49.2
»fossa (of)
  »pterygoid
C49.0C79.89D21.0D48.1D49.2
»glomus
C49.5C79.89D21.5D48.1D49.2
»glomus
  »coccygeal
C49.5C79.89D21.5D48.1D49.2
»great vessels NEC
C49.3C79.89D21.3D48.1D49.2
»lymph, lymphatic channel NEC
C49.9C79.89D21.9D48.1D49.2
»lymph, lymphatic channel NEC
  »vessel [See Also: Neoplasm, connective tissue]
C49.9C79.89D21.9D48.1D49.2
»pterygoid fossa
C49.0C79.89D21.0D48.1D49.2
»thorax, thoracic (cavity) (organs NEC)
  »duct
C49.3C79.89D21.3D48.1D49.2
»vena cava (abdominal) (inferior)
C49.4C79.89D21.4D48.1D49.2
»vena cava (abdominal) (inferior)
  »superior
C49.3C79.89D21.3D48.1D49.2

Information for Patients


Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


[Learn More]