2021 ICD-10-CM Code D48.1

Neoplasm of uncertain behavior of connective and other soft tissue

Version 2021

Valid for Submission

D48.1 is a billable diagnosis code used to specify a medical diagnosis of neoplasm of uncertain behavior of connective and other soft tissue. The code D48.1 is valid during the fiscal year 2021 from October 01, 2020 through September 30, 2021 for the submission of HIPAA-covered transactions.

The ICD-10-CM code D48.1 might also be used to specify conditions or terms like aggressive angiomyxoma, aggressive fibromatosis, alport syndrome, alport syndrome x-linked, angiomyxoma , atypical fibrous histiocytoma of soft tissue, etc.

The following anatomical sites found in the Table of Neoplasms apply to this code given the correct histological behavior: Neoplasm, neoplastic abdomen, abdominal wall [See Also: Neoplasm, abdomen, wall, skin] connective tissue ; Neoplasm, neoplastic adipose tissue [See Also: Neoplasm, connective tissue] ; Neoplasm, neoplastic aorta (thoracic) ; Neoplasm, neoplastic aorta (thoracic) abdominal ; Neoplasm, neoplastic aponeurosis ; Neoplasm, neoplastic aponeurosis palmar ; Neoplasm, neoplastic aponeurosis plantar ; etc

ICD-10:D48.1
Short Description:Neoplasm of uncertain behavior of connctv/soft tiss
Long Description:Neoplasm of uncertain behavior of connective and other soft tissue

Code Classification

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D48.1:


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D48.1 are found in the index:

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

Convert D48.1 to ICD-9 Code

The General Equivalency Mapping (GEM) crosswalk indicates an approximate mapping between the ICD-10 code D48.1 its ICD-9 equivalent. The approximate mapping means there is not an exact match between the ICD-10 code and the ICD-9 code and the mapped code is not a precise representation of the original code.

Table of Neoplasms

The code D48.1 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »abdomen, abdominal
    »wall [See Also: Neoplasm, abdomen, wall, skin]
      »connective tissue
C49.4C79.8D21.4D48.1D49.2
»Neoplasm, neoplastic
  »adipose tissue [See Also: Neoplasm, connective tissue]
C49.4C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »aorta (thoracic)
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »aorta (thoracic)
    »abdominal
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »aponeurosis
C49.9C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »aponeurosis
    »palmar
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »aponeurosis
    »plantar
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »carotid (artery)
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
    »auricular
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
    »ear (external)
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
    »eyelid
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
    »pinna
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »coccygeal
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »coccygeal
    »body or glomus
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
C49.9C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »abdomen
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »abdominal wall
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »ankle
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »antecubital fossa or space
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »arm
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »auricle (ear)
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »axilla
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »back
C49.6C79.89D21.6D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »buttock
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »calf
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »cervical region
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »cheek
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »chest (wall)
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »chin
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »diaphragm
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »ear (external)
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »elbow
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »extrarectal
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »extremity
C49.9C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »extremity
      »lower
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »extremity
      »upper
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »eyelid
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »face
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »finger
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »flank
C49.6C79.89D21.6D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »foot
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »forearm
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »forehead
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »gastric
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »gastrointestinal
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »gluteal region
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »great vessels NEC
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »groin
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »hand
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »head
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »heel
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »hip
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »hypochondrium
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »iliopsoas muscle
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »infraclavicular region
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »inguinal (canal) (region)
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »intestinal
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »intrathoracic
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »ischiorectal fossa
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »jaw
C03.9C79.89D00.03D10.39D48.1D49.0
»Neoplasm, neoplastic
  »connective tissue NEC
    »knee
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »leg
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »limb NEC
C49.9C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »limb NEC
      »lower
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »limb NEC
      »upper
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »nates
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »neck
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »orbit
C69.6C79.49D09.2D31.6D48.1D49.89
»Neoplasm, neoplastic
  »connective tissue NEC
    »pararectal
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »para-urethral
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »paravaginal
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »pelvis (floor)
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »pelvo-abdominal
C49.8C79.89D21.6D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »perineum
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »perirectal (tissue)
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »periurethral (tissue)
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »popliteal fossa or space
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »presacral
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »psoas muscle
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »pterygoid fossa
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »rectovaginal septum or wall
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »rectovesical
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »sacrococcygeal region
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »scalp
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »scapular region
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »shoulder
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »stomach
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »submental
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »supraclavicular region
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »temple
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »temporal region
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »thigh
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »thoracic (duct) (wall)
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »thorax
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »thumb
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »toe
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »trunk
C49.6C79.89D21.6D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »umbilicus
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »vesicorectal
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »wrist
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »diaphragm
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »ear (external) [See Also: Neoplasm, skin, ear]
    »cartilage
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »eyelid (lower) (skin) (upper)
    »cartilage
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »fascia [See Also: Neoplasm, connective tissue]
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »fascia [See Also: Neoplasm, connective tissue]
    »palmar
C49.1C79.89D21.1D48.1D49.2
»Neoplasm, neoplastic
  »fascia [See Also: Neoplasm, connective tissue]
    »plantar
C49.2C79.89D21.2D48.1D49.2
»Neoplasm, neoplastic
  »fossa (of)
    »pterygoid
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »glomus
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »glomus
    »coccygeal
C49.5C79.89D21.5D48.1D49.2
»Neoplasm, neoplastic
  »great vessels NEC
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »lymph, lymphatic channel NEC
C49.9C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »lymph, lymphatic channel NEC
    »vessel [See Also: Neoplasm, connective tissue]
C49.9C79.89D21.9D48.1D49.2
»Neoplasm, neoplastic
  »pterygoid fossa
C49.0C79.89D21.0D48.1D49.2
»Neoplasm, neoplastic
  »thorax, thoracic (cavity) (organs NEC)
    »duct
C49.3C79.89D21.3D48.1D49.2
»Neoplasm, neoplastic
  »vena cava (abdominal) (inferior)
C49.4C79.89D21.4D48.1D49.2
»Neoplasm, neoplastic
  »vena cava (abdominal) (inferior)
    »superior
C49.3C79.89D21.3D48.1D49.2

Information for Patients


Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


[Learn More in MedlinePlus]

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)