ICD-10 Diagnosis Code D48.1

Neoplasm of uncertain behavior of connctv/soft tiss

Diagnosis Code D48.1

ICD-10: D48.1
Short Description: Neoplasm of uncertain behavior of connctv/soft tiss
Long Description: Neoplasm of uncertain behavior of connective and other soft tissue
This is the 2019 version of the ICD-10-CM diagnosis code D48.1

Valid for Submission
The code D48.1 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Neoplasms (C00–D48)
    • Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
      • Neoplasm of uncertain behavior of other and unsp sites (D48)


Version 2019 Billable Code Neoplasm Uncertain Behavior

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code D48.1 is grouped in the following Diagnostic Related Group(s) (MS-DRG V35.0)

  • 564 - OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH MCC
  • 565 - OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITH CC
  • 566 - OTHER MUSCULOSKELETAL SYSTEM AND CONNECTIVE TISSUE DIAGNOSES WITHOUT CC/MCC

Convert to ICD-9
  • 238.1 - Unc behav neo soft tissu (Approximate Flag)

Synonyms
  • Aggressive angiomyxoma
  • Aggressive fibromatosis
  • Alport syndrome X-linked
  • Angiomyxoma
  • Atypical fibrous histiocytoma of soft tissue
  • Atypical fibrous histiocytoma of soft tissue
  • Atypical fibroxanthoma - spindle cell type
  • Atypical fibroxanthoma of skin
  • Atypical lipoma of soft tissue
  • Chondromatosis
  • Chondromatosis of synovium of hip joint
  • Chondromatosis of synovium of knee joint
  • Chondromatosis of synovium of temporomandibular joint
  • Composite hemangioendothelioma
  • Congenital nephritis
  • Desmoplastic fibroma of lower limb
  • Epithelioid hemangioendothelioma
  • Extragastrointestinal stromal tumor of peritoneum
  • Giant cell tumor of synovium and/or tendon sheath
  • Hemangiopericytoma
  • Kaposiform hemangioendothelioma
  • Lymphangiomyomatosis of connective tissue
  • Myxoma
  • Neoplasm of coccygeal body
  • Neoplasm of diaphragm
  • Neoplasm of great vessels
  • Neoplasm of muscle of abdomen
  • Neoplasm of muscle of buttock
  • Neoplasm of muscle of face
  • Neoplasm of muscle of hip
  • Neoplasm of muscle of hip
  • Neoplasm of muscle of inguinal region
  • Neoplasm of muscle of neck
  • Neoplasm of muscle of perineum
  • Neoplasm of muscle of shoulder
  • Neoplasm of muscle of thorax
  • Neoplasm of muscle of thorax
  • Neoplasm of muscle of upper limb
  • Neoplasm of muscle of upper limb
  • Neoplasm of soft tissues of hip
  • Neoplasm of soft tissues of inguinal region
  • Neoplasm of soft tissues of neck
  • Neoplasm of soft tissues of shoulder
  • Neoplasm of uncertain behavior of axilla
  • Neoplasm of uncertain behavior of blood vessel
  • Neoplasm of uncertain behavior of coccygeal body
  • Neoplasm of uncertain behavior of connective and soft tissue
  • Neoplasm of uncertain behavior of diaphragm
  • Neoplasm of uncertain behavior of great vessels
  • Neoplasm of uncertain behavior of inguinal region
  • Neoplasm of uncertain behavior of inguinal region
  • Neoplasm of uncertain behavior of muscle
  • Neoplasm of uncertain behavior of muscle of abdomen
  • Neoplasm of uncertain behavior of muscle of buttock
  • Neoplasm of uncertain behavior of muscle of face
  • Neoplasm of uncertain behavior of muscle of head
  • Neoplasm of uncertain behavior of muscle of hip
  • Neoplasm of uncertain behavior of muscle of inguinal region
  • Neoplasm of uncertain behavior of muscle of lower limb
  • Neoplasm of uncertain behavior of muscle of neck
  • Neoplasm of uncertain behavior of muscle of pelvis
  • Neoplasm of uncertain behavior of muscle of perineum
  • Neoplasm of uncertain behavior of muscle of shoulder
  • Neoplasm of uncertain behavior of muscle of thorax
  • Neoplasm of uncertain behavior of muscle of trunk
  • Neoplasm of uncertain behavior of muscle of upper limb
  • Neoplasm of uncertain behavior of paraganglia
  • Neoplasm of uncertain behavior of shoulder
  • Neoplasm of uncertain behavior of shoulder
  • Neoplasm of uncertain behavior of soft tissues
  • Neoplasm of uncertain behavior of soft tissues of abdomen
  • Neoplasm of uncertain behavior of soft tissues of axilla
  • Neoplasm of uncertain behavior of soft tissues of buttock
  • Neoplasm of uncertain behavior of soft tissues of face
  • Neoplasm of uncertain behavior of soft tissues of head
  • Neoplasm of uncertain behavior of soft tissues of hip
  • Neoplasm of uncertain behavior of soft tissues of inguinal region
  • Neoplasm of uncertain behavior of soft tissues of lower limb
  • Neoplasm of uncertain behavior of soft tissues of neck
  • Neoplasm of uncertain behavior of soft tissues of pelvis
  • Neoplasm of uncertain behavior of soft tissues of perineum
  • Neoplasm of uncertain behavior of soft tissues of shoulder
  • Neoplasm of uncertain behavior of soft tissues of thorax
  • Neoplasm of uncertain behavior of soft tissues of trunk
  • Neoplasm of uncertain behavior of soft tissues of upper limb
  • Periosteal desmoid
  • Pleomorphic hyalinizing angiectatic tumor of soft tissue
  • Reactive fibrous tissue proliferation
  • Retiform hemangioendothelioma
  • Soft tissue lesion of shoulder region
  • Superficial angiomyxoma
  • Synovial chondromatosis
  • X-linked diffuse leiomyomatosis with Alport syndrome

Index to Diseases and Injuries
References found for the code D48.1 in the Index to Diseases and Injuries:


Tabular List of Diseases and Injuries
References found for the code D48.1 in the Tabular List of Diseases and Injuries:

  • Inclusion Terms:
    • Neoplasm of uncertain behavior of conNEC tive tissue of ear
    • Neoplasm of uncertain behavior of conNEC tive tissue of eyelid
    • Stromal tumors of uncertain behavior of digestive system
  • Type 1 Excludes Notes:
    • neoplasm of uncertain behavior of articular cartilage (D48.0)
    • neoplasm of uncertain behavior of cartilage of larynx (D38.0)
    • neoplasm of uncertain behavior of cartilage of nose (D38.5)
    • neoplasm of uncertain behavior of conNEC tive tissue of breast (D48.6-)

Table of Neoplasms

The code D48.1 is included in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

The Tabular must be reviewed for the complete diagnosis code.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»abdomen, abdominal
  »wall [See Also: Neoplasm, abdomen, wall, skin]
    »connective tissue
C49.4C79.8D21.4D48.1D49.2
»adipose tissue [See Also: Neoplasm, connective tissue]
C49.4C79.89D21.9D48.1D49.2
»aorta (thoracic)
C49.3C79.89D21.3D48.1D49.2
»aorta (thoracic)
  »abdominal
C49.4C79.89D21.4D48.1D49.2
»aponeurosis
C49.9C79.89D21.9D48.1D49.2
»aponeurosis
  »palmar
C49.1C79.89D21.1D48.1D49.2
»aponeurosis
  »plantar
C49.2C79.89D21.2D48.1D49.2
»carotid (artery)
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »auricular
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »ear (external)
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »eyelid
C49.0C79.89D21.0D48.1D49.2
»cartilage (articular) (joint) NEC [See Also: Neoplasm, bone]
  »pinna
C49.0C79.89D21.0D48.1D49.2
»coccygeal
C49.5C79.89D21.5D48.1D49.2
»coccygeal
  »body or glomus
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »abdomen
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »abdominal wall
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »ankle
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »antecubital fossa or space
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »arm
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »auricle (ear)
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »axilla
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »back
C49.6C79.89D21.6D48.1D49.2
»connective tissue NEC
  »buttock
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »calf
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »cervical region
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »cheek
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »chest (wall)
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »chin
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »diaphragm
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »ear (external)
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »elbow
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »extrarectal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »extremity
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »extremity
    »lower
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »extremity
    »upper
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »eyelid
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »face
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »finger
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »flank
C49.6C79.89D21.6D48.1D49.2
»connective tissue NEC
  »foot
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »forearm
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »forehead
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »gastric
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »gastrointestinal
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »gluteal region
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »great vessels NEC
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »groin
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »hand
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »head
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »heel
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »hip
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »hypochondrium
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »iliopsoas muscle
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »infraclavicular region
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »inguinal (canal) (region)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »intestinal
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »intrathoracic
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »ischiorectal fossa
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »jaw
C03.9C79.89D00.03D10.39D48.1D49.0
»connective tissue NEC
  »knee
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »leg
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »limb NEC
C49.9C79.89D21.9D48.1D49.2
»connective tissue NEC
  »limb NEC
    »lower
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »limb NEC
    »upper
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »nates
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »neck
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »orbit
C69.6C79.49D09.2D31.6D48.1D49.89
»connective tissue NEC
  »pararectal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »para-urethral
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »paravaginal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »pelvis (floor)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »pelvo-abdominal
C49.8C79.89D21.6D48.1D49.2
»connective tissue NEC
  »perineum
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »perirectal (tissue)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »periurethral (tissue)
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »popliteal fossa or space
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »presacral
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »psoas muscle
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »pterygoid fossa
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »rectovaginal septum or wall
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »rectovesical
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »sacrococcygeal region
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »scalp
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »scapular region
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »shoulder
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »stomach
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »submental
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »supraclavicular region
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »temple
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »temporal region
C49.0C79.89D21.0D48.1D49.2
»connective tissue NEC
  »thigh
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »thoracic (duct) (wall)
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »thorax
C49.3C79.89D21.3D48.1D49.2
»connective tissue NEC
  »thumb
C49.1C79.89D21.1D48.1D49.2
»connective tissue NEC
  »toe
C49.2C79.89D21.2D48.1D49.2
»connective tissue NEC
  »trunk
C49.6C79.89D21.6D48.1D49.2
»connective tissue NEC
  »umbilicus
C49.4C79.89D21.4D48.1D49.2
»connective tissue NEC
  »vesicorectal
C49.5C79.89D21.5D48.1D49.2
»connective tissue NEC
  »wrist
C49.1C79.89D21.1D48.1D49.2
»diaphragm
C49.3C79.89D21.3D48.1D49.2
»ear (external) [See Also: Neoplasm, skin, ear]
  »cartilage
C49.0C79.89D21.0D48.1D49.2
»eyelid (lower) (skin) (upper)
  »cartilage
C49.0C79.89D21.0D48.1D49.2
»fascia [See Also: Neoplasm, connective tissue]
C49.1C79.89D21.1D48.1D49.2
»fascia [See Also: Neoplasm, connective tissue]
  »palmar
C49.1C79.89D21.1D48.1D49.2
»fascia [See Also: Neoplasm, connective tissue]
  »plantar
C49.2C79.89D21.2D48.1D49.2
»fossa (of)
  »pterygoid
C49.0C79.89D21.0D48.1D49.2
»glomus
C49.5C79.89D21.5D48.1D49.2
»glomus
  »coccygeal
C49.5C79.89D21.5D48.1D49.2
»great vessels NEC
C49.3C79.89D21.3D48.1D49.2
»lymph, lymphatic channel NEC
C49.9C79.89D21.9D48.1D49.2
»lymph, lymphatic channel NEC
  »vessel [See Also: Neoplasm, connective tissue]
C49.9C79.89D21.9D48.1D49.2
»pterygoid fossa
C49.0C79.89D21.0D48.1D49.2
»thorax, thoracic (cavity) (organs NEC)
  »duct
C49.3C79.89D21.3D48.1D49.2
»vena cava (abdominal) (inferior)
C49.4C79.89D21.4D48.1D49.2
»vena cava (abdominal) (inferior)
  »superior
C49.3C79.89D21.3D48.1D49.2

Information for Patients


Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

  • Dupuytrens contracture (Medical Encyclopedia)

[Read More]

ICD-10 Footnotes

General Equivalence Map Definitions
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Approximate Flag - The approximate flag is on, indicating that the relationship between the code in the source system and the code in the target system is an approximate equivalent.
  • No Map Flag - The no map flag indicates that a code in the source system is not linked to any code in the target system.
  • Combination Flag - The combination flag indicates that more than one code in the target system is required to satisfy the full equivalent meaning of a code in the source system.

Index of Diseases and Injuries Definitions

  • And - The word "and" should be interpreted to mean either "and" or "or" when it appears in a title.
  • Code also note - A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
  • Code first - Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
  • Type 1 Excludes Notes - A type 1 Excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Type 2 Excludes Notes - A type 2 Excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • Includes Notes - This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
  • Inclusion terms - List of terms is included under some codes. These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • NEC "Not elsewhere classifiable" - This abbreviation in the Alphabetic Index represents "other specified". When a specific code is not available for a condition, the Alphabetic Index directs the coder to the "other specified” code in the Tabular List.
  • NOS "Not otherwise specified" - This abbreviation is the equivalent of unspecified.
  • See - The "see" instruction following a main term in the Alphabetic Index indicates that another term should be referenced. It is necessary to go to the main term referenced with the "see" note to locate the correct code.
  • See Also - A "see also" instruction following a main term in the Alphabetic Index instructs that there is another main term that may also be referenced that may provide additional Alphabetic Index entries that may be useful. It is not necessary to follow the "see also" note when the original main term provides the necessary code.
  • 7th Characters - Certain ICD-10-CM categories have applicable 7th characters. The applicable 7th character is required for all codes within the category, or as the notes in the Tabular List instruct. The 7th character must always be the 7th character in the data field. If a code that requires a 7th character is not 6 characters, a placeholder X must be used to fill in the empty characters.
  • With - The word "with" should be interpreted to mean "associated with" or "due to" when it appears in a code title, the Alphabetic Index, or an instructional note in the Tabular List. The word "with" in the Alphabetic Index is sequenced immediately following the main term, not in alphabetical order.

Present on Admission
The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement.

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