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  6. 2026 ICD-10-CM Code C90

2026 ICD-10-CM Diagnosis Code C90

Multiple myeloma and malignant plasma cell neoplasms

ICD-10-CM Code:
C90
ICD-10 Code for:
Multiple myeloma and malignant plasma cell neoplasms
Is Billable?
Not Valid for Submission
Code Navigator:

C90 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of multiple myeloma and malignant plasma cell neoplasms. The code is not specific and is NOT valid for the year 2026 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Multiple myeloma and malignant plasma cell neoplasms

Non-specific codes like C90 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for multiple myeloma and malignant plasma cell neoplasms:

  • C90.0 for Multiple myeloma - NON-BILLABLE CODE

  • Use C90.00 for Multiple myeloma not having achieved remission - BILLABLE CODE

  • Use C90.01 for Multiple myeloma in remission - BILLABLE CODE

  • Use C90.02 for Multiple myeloma in relapse - BILLABLE CODE

  • C90.1 for Plasma cell leukemia - NON-BILLABLE CODE

  • Use C90.10 for Plasma cell leukemia not having achieved remission - BILLABLE CODE

  • Use C90.11 for Plasma cell leukemia in remission - BILLABLE CODE

  • Use C90.12 for Plasma cell leukemia in relapse - BILLABLE CODE

  • C90.2 for Extramedullary plasmacytoma - NON-BILLABLE CODE

  • Use C90.20 for Extramedullary plasmacytoma not having achieved remission - BILLABLE CODE

  • Use C90.21 for Extramedullary plasmacytoma in remission - BILLABLE CODE

  • Use C90.22 for Extramedullary plasmacytoma in relapse - BILLABLE CODE

  • C90.3 for Solitary plasmacytoma - NON-BILLABLE CODE

  • Use C90.30 for Solitary plasmacytoma not having achieved remission - BILLABLE CODE

  • Use C90.31 for Solitary plasmacytoma in remission - BILLABLE CODE

  • Use C90.32 for Solitary plasmacytoma in relapse - BILLABLE CODE

Code Classification

  • Neoplasms
    C00–D49
    • Malignant neoplasms of lymphoid, hematopoietic and related tissue
      C81-C96
      • Multiple myeloma and malignant plasma cell neoplasms
        C90

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues Z85.79

Patient Education


Cancer

What is cancer?

Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor.

Tumors can be benign or malignant. Benign tumors aren't cancer, while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of your body. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the type of cancer and how advanced it is.

What are the types of cancer?

There are more than 100 different types of cancer. Cancer can start almost anywhere in your body. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast.

Cancer may also be described by the type of cell that formed it, such as sarcoma if cancer begins in your bone and soft tissue. Carcinoma is the most common type of cancer. It is formed by epithelial cells, the cells that cover the inside and outside surfaces of your body.

How does cancer develop?

Cancer is a genetic disease. That means changes in your genes cause it. Changes in your genes are also called gene variants or mutations. Genes are parts of DNA in your cells that you inherit from your parents. However, only some cancers are caused by genes passed down from your parents.

Genetic changes can occur to your genes over your lifetime that affect how your cells function. Usually, your body gets rid of damaged cells before they turn cancerous, but this ability goes down as you age. Other factors that may affect your risk of developing cancer can include:

  • Exposure to ultraviolet (UV) rays from the sun
  • Smoking
  • Your diet
  • Physical inactivity

What are the symptoms of cancer?

Cancer symptoms depend on the type of cancer. For example, some of the symptoms that cancer may cause can include:

  • A lump in your breast
  • Blood in your urine (pee) or stool (poop)
  • Bleeding or bruising for no known reason
  • A sore that doesn't heal
  • Trouble swallowing
  • A new mole or a change to a mole you already have

Cancer may cause various symptoms but often doesn't cause pain. Don't wait until you're having pain before seeing your health care provider. See your provider if you have symptoms that don't get better in a few weeks.

How is cancer diagnosed?

There is no single test that can diagnose cancer. The tests ordered are usually based on your symptoms. Your provider may:

  • Ask about your medical history
  • Ask about your family health history, including relatives who have had cancer
  • Do a physical exam
  • Do a screening test such as a mammogram, colonoscopy, or a Pap test
  • Order blood tests or imaging tests

To find out if you have cancer, your provider may order a biopsy. A biopsy is the procedure of removing and examining tissue, cells, or fluids from your body.

What are the treatments for cancer?

Treatment depends on the type of cancer and how advanced it is. Most treatment plans may include surgery, radiation, and/or chemotherapy. Some may involve hormone therapy, immunotherapy or other types of biological therapy, or stem cell transplantation.

Can cancer be prevented?

It's usually not possible to know exactly why cancer develops in some people but not others. There are some things that you can't control which may increase or decrease your risk of getting cancer, such as inheriting certain genes or your age. But some lifestyle habits may increase your risk of certain types of cancer. Avoid or reduce lifestyle habits such as:

  • Smoking and tobacco use
  • Having too much sun exposure
  • Drinking too much alcohol
  • Not getting enough physical activity
  • Having obesity

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Plasma Cell Neoplasms (Including Multiple Myeloma) Treatment (PDQ®)

Learn about plasma cell neoplasm (including multiple myeloma) risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Code History

  • FY 2026 - No Change, effective from 10/1/2025 through 9/30/2026
  • FY 2025 - No Change, effective from 10/1/2024 through 9/30/2025
  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.