2027 ICD-10-CM Diagnosis Code C90Multiple myeloma and malignant plasma cell neoplasms

ICD-10-CM Codes›C00–D49›C81-C96›C90

ICD-10-CM C90
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

C90 is a non-billable ICD-10-CM category code for multiple myeloma and malignant plasma cell neoplasms, so it cannot be submitted on claims. Use a more specific code from this category instead, such as C90.00, C90.01, C90.02, and C90.10.

Code Identity

ICD-10-CM Code
C90
Billable Status
No — Non-Billable Category
Code Describes
Multiple myeloma and malignant plasma cell neoplasms
Short Description
Multiple myeloma and malignant plasma cell neoplasms
Same as the full description in the CMS dataset.
Chapter
C81-C96
Malignant neoplasms of lymphoid, hematopoietic and related tissue

Code Classification

ChapterC00–D49Neoplasms
SectionC81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue
CategoryC90Multiple myeloma and malignant plasma cell neoplasms
This CodeC90Multiple myeloma and malignant plasma cell neoplasms

Specific Coding for Multiple myeloma and malignant plasma cell neoplasmsOverview

Non-specific codes like C90 require more characters. Use one of these billable codes instead:

  • C90.0 for Multiple myeloma

  • Use C90.00 for Multiple myeloma not having achieved remission

  • Use C90.01 for Multiple myeloma in remission

  • Use C90.02 for Multiple myeloma in relapse

  • C90.1 for Plasma cell leukemia

  • Use C90.10 for Plasma cell leukemia not having achieved remission

  • Use C90.11 for Plasma cell leukemia in remission

  • Use C90.12 for Plasma cell leukemia in relapse

  • C90.2 for Extramedullary plasmacytoma

  • Use C90.20 for Extramedullary plasmacytoma not having achieved remission

  • Use C90.21 for Extramedullary plasmacytoma in remission

  • Use C90.22 for Extramedullary plasmacytoma in relapse

  • C90.3 for Solitary plasmacytoma

  • Use C90.30 for Solitary plasmacytoma not having achieved remission

  • Use C90.31 for Solitary plasmacytoma in remission

  • Use C90.32 for Solitary plasmacytoma in relapse

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to C90: its own notes plus those printed at block C81-C96 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue applies to 533 codes
  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name C90, its category, or a range that includes it.

Applicable To 1

These notes mention C90.

  • Z85.79 Personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues
    Conditions classifiable to C88-C90, C96 names C88-C90, which includes this code

Patient EducationClinical

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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About C90Overview

What is the ICD-10 code for multiple myeloma and malignant plasma cell neoplasms?

C90 is the ICD-10-CM category for multiple myeloma and malignant plasma cell neoplasms, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is C90 (Multiple myeloma and malignant plasma cell neoplasms) a billable code?

No. This is a category header that groups the codes for multiple myeloma and malignant plasma cell neoplasms, and headers cannot be submitted on claims. Claims for multiple myeloma and malignant plasma cell neoplasms need a more specific code from this category, such as C90.00, C90.01, and C90.02.

Can C90 be reported with Z85.79?

Not as a rule. The Excludes1 note on C90 lists "personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).