2027 ICD-10-CM Diagnosis Code C80Malignant neoplasm without specification of site

ICD-10-CM Codes›C00–D49›C76-C80›C80

ICD-10-CM C80
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

C80 is a non-billable ICD-10-CM category code for malignant neoplasm without specification of site, so it cannot be submitted on claims. Use a more specific code from this category instead, such as C80.0, C80.1, and C80.2.

Code Identity

ICD-10-CM Code
C80
Billable Status
No — Non-Billable Category
Code Describes
Malignant neoplasm without specification of site
Short Description
Malignant neoplasm without specification of site
Same as the full description in the CMS dataset.
Chapter
C76-C80
Malignant neoplasms of ill-defined, other secondary and unspecified sites

Code Classification

ChapterC00–D49Neoplasms
SectionC76-C80Malignant neoplasms of ill-defined, other secondary and unspecified sites
CategoryC80Malignant neoplasm without specification of site
This CodeC80Malignant neoplasm without specification of site

Specific Coding for Malignant neoplasm without specification of siteOverview

Non-specific codes like C80 require more characters. Use one of these billable codes instead:

  • Use C80.0 for Disseminated malignant neoplasm, unspecified

  • Use C80.1 for Malignant (primary) neoplasm, unspecified

  • Use C80.2 for Malignant neoplasm associated with transplanted organ

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to C80: its own notes plus those printed at Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • malignant carcinoid tumor of unspecified site (C7A.00)
  • malignant neoplasm of specified multiple sites- code to each site

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

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Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About C80Overview

What is the ICD-10 code for malignant neoplasm without specification of site?

C80 is the ICD-10-CM category for malignant neoplasm without specification of site, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is C80 (Malignant neoplasm without specification of site) a billable code?

No. This is a category header that groups the codes for malignant neoplasm without specification of site, and headers cannot be submitted on claims. Claims for malignant neoplasm without specification of site need a more specific code from this category, such as C80.0, C80.1, and C80.2.

Can C80 be reported with C7A.00?

Not as a rule. The Excludes1 note on C80 lists "malignant carcinoid tumor of unspecified site (C7A.00)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).