2026 ICD-10-CM Diagnosis Code C80Malignant neoplasm without specification of site

ICD-10-CM CodesC00–D49C76-C80C80

ICD-10-CM C80
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C80 is a non-billable ICD-10-CM category code for malignant neoplasm without specification of site, so it cannot be submitted on claims. Use a more specific code from this category instead, such as C80.0, C80.1, and C80.2.

Code Identity

ICD-10-CM Code
C80
Billable Status
No — Non-Billable Category
Code Describes
Malignant neoplasm without specification of site
Short Description
Malignant neoplasm without specification of site
Same as the full description in the CMS dataset.
Chapter
C76-C80
Malignant neoplasms of ill-defined, other secondary and unspecified sites

Code Classification

ChapterC00–D49Neoplasms
SectionC76-C80Malignant neoplasms of ill-defined, other secondary and unspecified sites
CategoryC80Malignant neoplasm without specification of site
This CodeC80Malignant neoplasm without specification of site

Specific Coding for Malignant neoplasm without specification of siteOverview

Non-specific codes like C80 require more characters. Use one of these billable codes instead:

  • Use C80.0 for Disseminated malignant neoplasm, unspecified

  • Use C80.1 for Malignant (primary) neoplasm, unspecified

  • Use C80.2 for Malignant neoplasm associated with transplanted organ

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • malignant carcinoid tumor of unspecified site C7A.00
  • malignant neoplasm of specified multiple sites- code to each site

Patient EducationClinical

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Read the full article at MedlinePlus

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Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C80Overview

Is C80 (Malignant neoplasm without specification of site) a billable code?

No. This is a category header that groups the codes for malignant neoplasm without specification of site, and headers cannot be submitted on claims. Claims for malignant neoplasm without specification of site need a more specific code from this category, such as C80.0, C80.1, and C80.2.