2026 ICD-10-CM Diagnosis Code D43Neoplasm of uncertain behavior of brain and central nervous system

ICD-10-CM Codes›C00–D49›D37-D48›D43

ICD-10-CM D43
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D43 is a non-billable ICD-10-CM category code for neoplasm of uncertain behavior of brain and central nervous system, so it cannot be submitted on claims. Use a more specific code from this category instead, such as D43.0, D43.1, D43.2, and D43.3.

Code Identity

ICD-10-CM Code
D43
Billable Status
No — Non-Billable Category
Code Describes
Neoplasm of uncertain behavior of brain and central nervous system
Chapter
D37-D48
Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD43Neoplasm of uncertain behavior of brain and central nervous system
This CodeD43Neoplasm of uncertain behavior of brain and central nervous system

Specific Coding for Neoplasm of uncertain behavior of brain and cnslOverview

Non-specific codes like D43 require more characters. Use one of these billable codes instead:

  • Use D43.0 for Neoplasm of uncertain behavior of brain, supratentorial

  • Use D43.1 for Neoplasm of uncertain behavior of brain, infratentorial

  • Use D43.2 for Neoplasm of uncertain behavior of brain, unspecified

  • Use D43.3 for Neoplasm of uncertain behavior of cranial nerves

  • Use D43.4 for Neoplasm of uncertain behavior of spinal cord

  • Use D43.8 for Neoplasm of uncertain behavior of other specified parts of central nervous system

  • Use D43.9 for Neoplasm of uncertain behavior of central nervous system, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • neoplasm of uncertain behavior of peripheral nerves and autonomic nervous system D48.2

Patient EducationClinical

Brain Diseases

Your brain is the control center of your body. It controls your thoughts, memory, speech, and movement. It regulates the function of many organs. It's part of your nervous system, which also includes your spinal cord and peripheral nerves. The nervous system sends signals between your brain and the rest of the body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D43Overview

Is D43 a billable code?

No. This is a category header that groups the codes for neoplasm of uncertain behavior of brain and central nervous system, and headers cannot be submitted on claims. Claims for neoplasm of uncertain behavior of brain and central nervous system need a more specific code from this category, such as D43.0, D43.1, and D43.2.