2026 ICD-10-CM Diagnosis Code D45Polycythemia vera

ICD-10-CM CodesC00–D49D37-D48D45

ICD-10-CM D45
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D45 is a billable ICD-10-CM diagnosis code for polycythemia vera. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 820 through 825, 840 through 842. Coders also document this condition as chorea due to polycythemia rubra vera. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D45
Billable Status
Yes — Valid for Submission
Code Describes
Polycythemia vera
Chapter
D37-D48
Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD45Polycythemia vera
This CodeD45Polycythemia vera

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chorea due to polycythemia rubra vera
  • Erythrocytosis due to polycythemia vera
  • Myelofibrosis
  • Myelofibrosis due to another disorder
  • Polycythemia vera
  • Polycythemia vera in remission
  • Post-polycythemia vera myelofibrosis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • familial polycythemia D75.0
  • secondary polycythemia D75.1

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Erythremia(acute)
      • chronic
    • Heilmeyer-Schoner disease
    • Polycythemia(secondary)
      • vera

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Polycythemia Vera

    a myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. hematopoiesis is also reactive in extramedullary sites (liver and spleen). in time myelofibrosis occurs.

Patient EducationClinical

Bone Marrow Diseases

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D45 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
207.10 Chr erythrm w/o ach rmsn
Approximate The match is approximate rather than exact.
ICD-9-CM
207.11 Chr erythrm w remision
Approximate The match is approximate rather than exact.
ICD-9-CM
207.12 Chr erythrmia in relapse
Approximate The match is approximate rather than exact.
ICD-9-CM
238.4 Polycythemia vera
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D45Overview

Is D45 (Polycythemia vera) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report polycythemia vera on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D45 group to?

When polycythemia vera is the principal diagnosis on an inpatient stay, it groups to MS-DRG 820, 821, 822, 823, 824, 825, 840, 841, 842, with relative weights from 1.0104 to 5.8648 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D45?

Under the General Equivalence Mappings, polycythemia vera converts to ICD-9-CM 207.10 (chr erythrm w/o ach rmsn), 207.11 (chr erythrm w remision), and 207.12 (chr erythrmia in relapse). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.