2026 ICD-10-CM Diagnosis Code C61Malignant neoplasm of prostate
ICD-10-CM Codes›C00–D49›C60-C63›C61
- Billable — Valid for Submission
- Chronic Condition
C61 is a billable ICD-10-CM diagnosis code for malignant neoplasm of prostate. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 715 through 716, 722 through 724. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Male reproductive system cancers - prostate.
Code Identity
Code Classification
Quality Payment Program MeasuresBilling
Medicare quality measures that can apply when C61 is part of the patient record.
Radical Prostatectomy Pathology Reporting
High Priority: NO
Measure Type: Process
Submission Methods: Claims, Registry
Description: Percentage of radical prostatectomy pathology reports that include the pT category, the pN category, the Gleason score and a statement about margin status.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acinar cell cystadenocarcinoma of prostate
- Adenocarcinoma of prostate
- Carcinoma of prostate
- Endometrioid carcinoma of prostate
- Extraprostatic extension of tumor present
- Extraprostatic extension of tumor present, focal
- Extraprostatic extension of tumor present, multifocal
- Extraprostatic extension of tumor present, non-focal
- Extraprostatic extension of tumor present, unifocal
- Familial prostate cancer
- Hormone refractory prostate cancer
- Hormone sensitive prostate cancer
- Infiltrating duct carcinoma of prostate
- Local recurrence of malignant neoplasm of prostate
- Malignant neoplasm involving urinary bladder by direct extension from prostate
- Malignant neoplasm of prostate
- Malignant neoplasm of seminal vesicle
- Malignant tumor involving an organ by direct extension from prostate
- Malignant tumor involving rectum by direct extension from prostate
- Malignant tumor involving seminal vesicle by direct extension from prostate
- Malignant tumor involving urethra by direct extension from prostate
- Malignant tumor involving vasa deferentia by direct extension from prostate
- Metastatic castration-resistant prostate cancer
- Neoplasm of seminal vesicle
- Non-metastatic prostate cancer
- Obstructive nephropathy due to malignancy
- Obstructive nephropathy due to prostate cancer
- Primary acinar cell cystadenocarcinoma of prostate
- Primary adenocarcinoma of prostate
- Primary carcinoma of prostate
- Primary endometrioid carcinoma of prostate
- Primary infiltrating duct carcinoma of prostate
- Primary malignant hormone-refractory neoplasm of prostate
- Primary malignant neoplasm of prostate
- Prostate cancer metastatic to eye
- Recurrent malignant neoplasm of prostate
- Squamous cell carcinoma of male genital
- Squamous cell carcinoma of prostate
- Tumor invasion of perineural tissue absent
- Tumor invasion of perineural tissue present
- Tumor invasion of periprostatic fat absent
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Use Additional Code
- code, if applicable, to identify:
- hormone sensitivity status Z19.1 Z19.2
- rising PSA following treatment for malignant neoplasm of prostate R97.21
Type 1 Excludes
- malignant neoplasm of seminal vesicle C63.7
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- Adenocarcinoma - See Also: Neoplasm, malignant, by site;
- Carcinoma (malignant) - See Also: Neoplasm, by site, malignant;
- male - C61
- Cystadenocarcinoma - See: Neoplasm, malignant, by site;
- endometrioid - See: Neoplasm, malignant, by site;
- male - C61
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- Adenocarcinoma
- duct
- unspecified site
- male
- Carcinoma(malignant)
- endometrioid
- unspecified site
- male
- Cystadenocarcinoma
- endometrioid
- unspecified site
- male
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Table of NeoplasmsClinical
Patient EducationClinical
Prostate Cancer
Cancer is a disease in which cells in the body grow out of control. Prostate cancer begins in the cells of the prostate. The prostate is a gland in the male reproductive system. It lies just below the bladder. It makes fluid that is part of semen.
The full article covers:
- What is prostate cancer?
- What causes prostate cancer?
- Who is more likely to develop prostate cancer?
- What are the symptoms of prostate cancer?
- What are prostate tests and how is prostate cancer diagnosed?
- What are the treatments for prostate cancer?
- Can prostate cancer be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert C61 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C61Overview
Is C61 (Malignant neoplasm of prostate) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of prostate on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does C61 group to?
When malignant neoplasm of prostate is the principal diagnosis on an inpatient stay, it groups to MS-DRG 715, 716, 722, 723, 724, with relative weights from 0.6117 to 2.2373 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of C61?
Under the General Equivalence Mappings, malignant neoplasm of prostate converts to ICD-9-CM 185 (malign neopl prostate). The mapping is a direct match.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
