2026 ICD-10-CM Diagnosis Code C52Malignant neoplasm of vagina

ICD-10-CM CodesC00–D49C51-C58C52

ICD-10-CM C52
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C52 is a billable ICD-10-CM diagnosis code for malignant neoplasm of vagina. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 736 through 741, 754 through 756. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Female reproductive system cancers - vagina.

Code Identity

ICD-10-CM Code
C52
Billable Status
Yes — Valid for Submission
Code Describes
Malignant neoplasm of vagina
Short Description
Malignant neoplasm of vagina
Same as the full description in the CMS dataset.
Chapter
C51-C58
Malignant neoplasms of female genital organs

Code Classification

ChapterC00–D49Neoplasms
SectionC51-C58Malignant neoplasms of female genital organs
CategoryC52Malignant neoplasm of vagina
This CodeC52Malignant neoplasm of vagina

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Carcinoma of vagina
  • Malignant germ cell neoplasm of vagina
  • Malignant neoplasm involving left fallopian tube by direct extension from vagina
  • Malignant neoplasm involving right fallopian tube by direct extension from vagina
  • Malignant neoplasm involving urinary bladder by direct extension from vagina
  • Malignant neoplasm of Gartner's duct
  • Malignant neoplasm of vagina
  • Malignant neoplasm of vaginal vault
  • Malignant tumor involving an organ by direct extension from vagina
  • Malignant tumor involving left ovary by direct extension from vagina
  • Malignant tumor involving rectum by direct extension from vagina
  • Malignant tumor involving right ovary by direct extension from vagina
  • Malignant tumor involving uterine cervix by direct extension from vagina
  • Malignant tumor involving uterine corpus by direct extension from vagina
  • Malignant tumor involving vulva by direct extension from vagina
  • Primary adenocarcinoma of vagina
  • Primary carcinoma of vagina
  • Primary malignant melanoma of vagina
  • Primary malignant neoplasm of vagina
  • Primary squamous cell carcinoma of vagina
  • Recurrent primary malignant neoplasm of vagina
  • Sarcoma of vulva
  • Squamous cell carcinoma of vagina
  • Vaginal intraepithelial neoplasia
  • Vulvovaginal rhabdomyosarcoma

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • carcinoma in situ of vagina D07.2

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO037
Female reproductive system cancers - vagina
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of NeoplasmsClinical

Anatomical sites in the Table of Neoplasms that reference this code family.

SiteMalig.
Primary
Malig.
Secondary
Ca
in situ
BenignUncertainUnspec.
fornix vaginaC52C79.82D07.2D28.1D39.8D49.59
Gartner's ductC52C79.82D07.2D28.1D39.8D49.59
hymenC52C79.82D07.2D28.1D39.8D49.59
vagina, vaginal (fornix) (vault) (wall)C52C79.82D07.2D28.1D39.8D49.59

Patient EducationClinical

Vaginal Cancer

Vaginal cancer is a rare type of cancer that starts in the vagina. The vagina is the canal leading from your cervix (the opening of your uterus) to the outside of your body.

The full article covers:

  • What is vaginal cancer?
  • Who is more likely to develop vaginal cancer?
  • What are the symptoms of vaginal cancer?
  • How is vaginal cancer diagnosed?
  • What are the treatments for vaginal cancer?
  • Can vaginal cancer be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C52 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
184.0 Malign neopl vagina
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C52Overview

Is C52 (Malignant neoplasm of vagina) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report malignant neoplasm of vagina on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C52 group to?

When malignant neoplasm of vagina is the principal diagnosis on an inpatient stay, it groups to MS-DRG 736, 737, 738, 739, 740, 741, 754, 755, 756, with relative weights from 0.9605 to 3.5745 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C52?

Under the General Equivalence Mappings, malignant neoplasm of vagina converts to ICD-9-CM 184.0 (malign neopl vagina). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.