2024 ICD-10-CM Diagnosis Code C52

Malignant neoplasm of vagina

ICD-10-CM Code:
ICD-10 Code for:
Malignant neoplasm of vagina
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Code Navigator:

Code Classification

  • Neoplasms
    • Malignant neoplasms of female genital organs
      • Malignant neoplasm of vagina

C52 is a billable diagnosis code used to specify a medical diagnosis of malignant neoplasm of vagina. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

This code is applicable to female patients only. It is clinically and virtually impossible to use this code on a non-female patient.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic fornix vagina or Neoplasm, neoplastic Gartner's duct or Neoplasm, neoplastic hymen or Neoplasm, neoplastic vagina, vaginal (fornix) (vault) (wall) .

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Carcinoma of vagina
  • Malignant germ cell neoplasm of vagina
  • Malignant neoplasm involving urinary bladder by direct extension from vagina
  • Malignant neoplasm of Gartner's duct
  • Malignant neoplasm of vaginal vault
  • Malignant tumor involving an organ by direct extension from vagina
  • Malignant tumor involving left fallopian tube by direct extension from vagina
  • Malignant tumor involving left ovary by direct extension from vagina
  • Malignant tumor involving rectum by direct extension from vagina
  • Malignant tumor involving right fallopian tube by direct extension from vagina
  • Malignant tumor involving right ovary by direct extension from vagina
  • Malignant tumor involving uterine cervix by direct extension from vagina
  • Malignant tumor involving uterine corpus by direct extension from vagina
  • Malignant tumor involving vulva by direct extension from vagina
  • Malignant tumor of vagina
  • Primary adenocarcinoma of vagina
  • Primary carcinoma of vagina
  • Primary malignant melanoma of vagina
  • Primary malignant neoplasm of vagina
  • Primary squamous cell carcinoma of vagina
  • Recurrent primary malignant neoplasm of vagina
  • Sarcoma of vulva
  • Squamous cell carcinoma of vagina
  • Vaginal intraepithelial neoplasia
  • Vaginal intraepithelial neoplasia
  • Vaginal intraepithelial neoplasia
  • Vaginal intraepithelial neoplasia
  • Vulvovaginal rhabdomyosarcoma

Clinical Classification

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • carcinoma in situ of vagina D07.2

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Diagnoses for females only - The Medicare Code Editor detects inconsistencies between a patient’s sex and any diagnosis on the patient’s record, these edits apply to FEMALES only .

Convert C52 to ICD-9-CM

  • ICD-9-CM Code: 184.0 - Malign neopl vagina

Table of Neoplasms

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
CaInSitu Benign Uncertain
»Neoplasm, neoplastic
»Neoplasm, neoplastic
  »Gartner's duct
»Neoplasm, neoplastic
»Neoplasm, neoplastic
  »vagina, vaginal (fornix) (vault) (wall)

Patient Education

Vaginal Cancer

Vaginal cancer is a rare type of cancer. It is more common in women 60 and older. You are also more likely to get it if you have had a human papillomavirus (HPV) infection or if your mother took diethylstilbestrol (DES) when she was pregnant. Doctors prescribed DES in the 1950's to prevent miscarriages. You are also at higher risk if you have had abnormal cells in the vagina, cervix, or uterus.

It often doesn't have early symptoms. However, see your doctor if you notice:

  • Bleeding that is not your period
  • A vaginal lump
  • Pelvic pain

A Pap test can find abnormal cells that may be cancer. Vaginal cancer can often be cured in its early stages. Treatment might include surgery, radiation therapy, and chemotherapy.

NIH: National Cancer Institute

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.