2027 ICD-10-CM Diagnosis Code C81Hodgkin lymphoma

ICD-10-CM Codes›C00–D49›C81-C96›C81

ICD-10-CM C81
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

C81 is a non-billable ICD-10-CM category code for hodgkin lymphoma, so it cannot be submitted on claims. Use a more specific code from this category instead, such as C81.00, C81.01, C81.02, and C81.03.

Code Identity

ICD-10-CM Code
C81
Billable Status
No — Non-Billable Category
Code Describes
Hodgkin lymphoma
Short Description
Hodgkin lymphoma
Same as the full description in the CMS dataset.
Chapter
C81-C96
Malignant neoplasms of lymphoid, hematopoietic and related tissue

Code Classification

ChapterC00–D49Neoplasms
SectionC81-C96Malignant neoplasms of lymphoid, hematopoietic and related tissue
CategoryC81Hodgkin lymphoma
This CodeC81Hodgkin lymphoma

Specific Coding for Hodgkin lymphomaOverview

Non-specific codes like C81 require more characters. Use one of these billable codes instead:

  • C81.0 for Nodular lymphocyte predominant Hodgkin lymphoma

  • Use C81.00 for Nodular lymphocyte predominant Hodgkin lymphoma, unspecified site

  • Use C81.01 for Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of head, face, and neck

  • Use C81.02 for Nodular lymphocyte predominant Hodgkin lymphoma, intrathoracic lymph nodes

  • Use C81.03 for Nodular lymphocyte predominant Hodgkin lymphoma, intra-abdominal lymph nodes

  • Use C81.04 for Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • Use C81.05 for Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

  • Use C81.06 for Nodular lymphocyte predominant Hodgkin lymphoma, intrapelvic lymph nodes

  • Use C81.07 for Nodular lymphocyte predominant Hodgkin lymphoma, spleen

  • Use C81.08 for Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites

  • Use C81.09 for Nodular lymphocyte predominant Hodgkin lymphoma, extranodal and solid organ sites

  • Use C81.0A for Nodular lymphocyte predominant Hodgkin lymphoma, in remission

  • C81.1 for Nodular sclerosis Hodgkin lymphoma

  • Use C81.10 for Nodular sclerosis Hodgkin lymphoma, unspecified site

  • Use C81.11 for Nodular sclerosis Hodgkin lymphoma, lymph nodes of head, face, and neck

  • Use C81.12 for Nodular sclerosis Hodgkin lymphoma, intrathoracic lymph nodes

  • Use C81.13 for Nodular sclerosis Hodgkin lymphoma, intra-abdominal lymph nodes

  • Use C81.14 for Nodular sclerosis Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • Use C81.15 for Nodular sclerosis Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

  • Use C81.16 for Nodular sclerosis Hodgkin lymphoma, intrapelvic lymph nodes

  • Use C81.17 for Nodular sclerosis Hodgkin lymphoma, spleen

  • Use C81.18 for Nodular sclerosis Hodgkin lymphoma, lymph nodes of multiple sites

  • Use C81.19 for Nodular sclerosis Hodgkin lymphoma, extranodal and solid organ sites

  • Use C81.1A for Nodular sclerosis Hodgkin lymphoma, in remission

  • C81.2 for Mixed cellularity Hodgkin lymphoma

  • Use C81.20 for Mixed cellularity Hodgkin lymphoma, unspecified site

  • Use C81.21 for Mixed cellularity Hodgkin lymphoma, lymph nodes of head, face, and neck

  • Use C81.22 for Mixed cellularity Hodgkin lymphoma, intrathoracic lymph nodes

  • Use C81.23 for Mixed cellularity Hodgkin lymphoma, intra-abdominal lymph nodes

  • Use C81.24 for Mixed cellularity Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • Use C81.25 for Mixed cellularity Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

  • Use C81.26 for Mixed cellularity Hodgkin lymphoma, intrapelvic lymph nodes

  • Use C81.27 for Mixed cellularity Hodgkin lymphoma, spleen

  • Use C81.28 for Mixed cellularity Hodgkin lymphoma, lymph nodes of multiple sites

  • Use C81.29 for Mixed cellularity Hodgkin lymphoma, extranodal and solid organ sites

  • Use C81.2A for Mixed cellularity Hodgkin lymphoma, in remission

  • C81.3 for Lymphocyte depleted Hodgkin lymphoma

  • Use C81.30 for Lymphocyte depleted Hodgkin lymphoma, unspecified site

  • Use C81.31 for Lymphocyte depleted Hodgkin lymphoma, lymph nodes of head, face, and neck

  • Use C81.32 for Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodes

  • Use C81.33 for Lymphocyte depleted Hodgkin lymphoma, intra-abdominal lymph nodes

  • Use C81.34 for Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • Use C81.35 for Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

  • Use C81.36 for Lymphocyte depleted Hodgkin lymphoma, intrapelvic lymph nodes

  • Use C81.37 for Lymphocyte depleted Hodgkin lymphoma, spleen

  • Use C81.38 for Lymphocyte depleted Hodgkin lymphoma, lymph nodes of multiple sites

  • Use C81.39 for Lymphocyte depleted Hodgkin lymphoma, extranodal and solid organ sites

  • Use C81.3A for Lymphocyte depleted Hodgkin lymphoma, in remission

  • C81.4 for Lymphocyte-rich Hodgkin lymphoma

  • Use C81.40 for Lymphocyte-rich Hodgkin lymphoma, unspecified site

  • Use C81.41 for Lymphocyte-rich Hodgkin lymphoma, lymph nodes of head, face, and neck

  • Use C81.42 for Lymphocyte-rich Hodgkin lymphoma, intrathoracic lymph nodes

  • Use C81.43 for Lymphocyte-rich Hodgkin lymphoma, intra-abdominal lymph nodes

  • Use C81.44 for Lymphocyte-rich Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • Use C81.45 for Lymphocyte-rich Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

  • Use C81.46 for Lymphocyte-rich Hodgkin lymphoma, intrapelvic lymph nodes

  • Use C81.47 for Lymphocyte-rich Hodgkin lymphoma, spleen

  • Use C81.48 for Lymphocyte-rich Hodgkin lymphoma, lymph nodes of multiple sites

  • Use C81.49 for Lymphocyte-rich Hodgkin lymphoma, extranodal and solid organ sites

  • Use C81.4A for Lymphocyte-rich Hodgkin lymphoma, in remission

  • C81.7 for Other Hodgkin lymphoma

  • Use C81.70 for Other Hodgkin lymphoma, unspecified site

  • Use C81.71 for Other Hodgkin lymphoma, lymph nodes of head, face, and neck

  • Use C81.72 for Other Hodgkin lymphoma, intrathoracic lymph nodes

  • Use C81.73 for Other Hodgkin lymphoma, intra-abdominal lymph nodes

  • Use C81.74 for Other Hodgkin lymphoma, lymph nodes of axilla and upper limb

  • Use C81.75 for Other Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

  • Use C81.76 for Other Hodgkin lymphoma, intrapelvic lymph nodes

  • Use C81.77 for Other Hodgkin lymphoma, spleen

  • Use C81.78 for Other Hodgkin lymphoma, lymph nodes of multiple sites

  • Use C81.79 for Other Hodgkin lymphoma, extranodal and solid organ sites

  • Use C81.7A for Other Hodgkin lymphoma, in remission

  • C81.9 for Hodgkin lymphoma, unspecified

  • Use C81.90 for Hodgkin lymphoma, unspecified, unspecified site

  • Use C81.91 for Hodgkin lymphoma, unspecified, lymph nodes of head, face, and neck

  • Use C81.92 for Hodgkin lymphoma, unspecified, intrathoracic lymph nodes

  • Use C81.93 for Hodgkin lymphoma, unspecified, intra-abdominal lymph nodes

  • Use C81.94 for Hodgkin lymphoma, unspecified, lymph nodes of axilla and upper limb

  • Use C81.95 for Hodgkin lymphoma, unspecified, lymph nodes of inguinal region and lower limb

  • Use C81.96 for Hodgkin lymphoma, unspecified, intrapelvic lymph nodes

  • Use C81.97 for Hodgkin lymphoma, unspecified, spleen

  • Use C81.98 for Hodgkin lymphoma, unspecified, lymph nodes of multiple sites

  • Use C81.99 for Hodgkin lymphoma, unspecified, extranodal and solid organ sites

  • Use C81.9A for Hodgkin lymphoma, unspecified, in remission

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to C81: its own notes plus those printed at block C81-C96 and Chapter 2. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • personal history of Hodgkin lymphoma (Z85.71)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block C81-C96 Malignant neoplasms of lymphoid, hematopoietic and related tissue applies to 533 codes
  • Kaposi's sarcoma of lymph nodes (C46.3)
  • secondary and unspecified neoplasm of lymph nodes (C77.-)
  • secondary neoplasm of bone marrow (C79.52)
  • secondary neoplasm of spleen (C78.89)

Notes

General instructions on how these codes are used.

From Chapter 2 (C00-D49) Neoplasms applies to 1,730 codes
  • Functional activity
  • All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
  • Morphology [Histology]
  • Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
  • Primary malignant neoplasms overlapping site boundaries
  • A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
  • Malignant neoplasm of ectopic tissue
  • Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name C81, its category, or a range that includes it.

Applicable To 1

These notes mention C81.

  • Z85.71 Personal history of Hodgkin lymphoma
    Conditions classifiable to C81

Excludes1 1

These codes carry an Excludes1 note naming C81: they are not reported together with it, unless the two conditions are unrelated.

  • C26.1 Malignant neoplasm of spleen
    Hodgkin lymphoma (C81.-)

Clinical InformationClinical

  • Hodgkin Disease

    a malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. in the classical variant, giant usually multinucleate hodgkin's and reed-sternberg cells are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.

Patient EducationClinical

Hodgkin Lymphoma

Hodgkin lymphoma, also called Hodgkin disease, is a type of cancer that develops in the lymph system. Your lymph system is part of your immune system. It helps protect your body from infection and disease.

The full article covers:

  • What is Hodgkin lymphoma?
  • What causes Hodgkin lymphoma?
  • Who is more likely to develop Hodgkin lymphoma?
  • What are the symptoms of Hodgkin lymphoma?
  • How is Hodgkin lymphoma diagnosed?
  • What are the treatments for Hodgkin lymphoma?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About C81Overview

What is the ICD-10 code for hodgkin lymphoma?

C81 is the ICD-10-CM category for hodgkin lymphoma, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is C81 (Hodgkin lymphoma) a billable code?

No. This is a category header that groups the codes for hodgkin lymphoma, and headers cannot be submitted on claims. Claims for hodgkin lymphoma need a more specific code from this category, such as C81.00, C81.01, and C81.02.

Can C81 be reported with Z85.71?

Not as a rule. The Excludes1 note on C81 lists "personal history of Hodgkin lymphoma (Z85.71)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).