ICD-10-CM Code C81

Hodgkin lymphoma

Version 2020 Non-Billable Code

Not Valid for Submission

C81 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of hodgkin lymphoma. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10:C81
Short Description:Hodgkin lymphoma
Long Description:Hodgkin lymphoma

Consider the following ICD-10 codes with a higher level of specificity:

  • C81.0 - Nodular lymphocyte predominant Hodgkin lymphoma
  • C81.00 - Nodular lymphocyte predominant ... unspecified site
  • C81.01 - Nodular lymphocyte predominant ... lymph nodes of head, face, and neck
  • C81.02 - Nodular lymphocyte predominant ... intrathoracic lymph nodes
  • C81.03 - Nodular lymphocyte predominant ... intra-abdominal lymph nodes
  • C81.04 - Nodular lymphocyte predominant ... lymph nodes of axilla and upper limb
  • C81.05 - Nodular lymphocyte predominant ... lymph nodes of inguinal region and lower limb
  • C81.06 - Nodular lymphocyte predominant ... intrapelvic lymph nodes
  • C81.07 - Nodular lymphocyte predominant ... spleen
  • C81.08 - Nodular lymphocyte predominant ... lymph nodes of multiple sites
  • C81.09 - Nodular lymphocyte predominant ... extranodal and solid organ sites
  • C81.1 - Nodular sclerosis Hodgkin lymphoma
  • C81.10 - Nodular sclerosis ... unspecified site
  • C81.11 - Nodular sclerosis ... lymph nodes of head, face, and neck
  • C81.12 - Nodular sclerosis ... intrathoracic lymph nodes
  • C81.13 - Nodular sclerosis ... intra-abdominal lymph nodes
  • C81.14 - Nodular sclerosis ... lymph nodes of axilla and upper limb
  • C81.15 - Nodular sclerosis ... lymph nodes of inguinal region and lower limb
  • C81.16 - Nodular sclerosis ... intrapelvic lymph nodes
  • C81.17 - Nodular sclerosis ... spleen
  • C81.18 - Nodular sclerosis ... lymph nodes of multiple sites
  • C81.19 - Nodular sclerosis ... extranodal and solid organ sites
  • C81.2 - Mixed cellularity Hodgkin lymphoma
  • C81.20 - Mixed cellularity ... unspecified site
  • C81.21 - Mixed cellularity ... lymph nodes of head, face, and neck
  • C81.22 - Mixed cellularity ... intrathoracic lymph nodes
  • C81.23 - Mixed cellularity ... intra-abdominal lymph nodes
  • C81.24 - Mixed cellularity ... lymph nodes of axilla and upper limb
  • C81.25 - Mixed cellularity ... lymph nodes of inguinal region and lower limb
  • C81.26 - Mixed cellularity ... intrapelvic lymph nodes
  • C81.27 - Mixed cellularity ... spleen
  • C81.28 - Mixed cellularity ... lymph nodes of multiple sites
  • C81.29 - Mixed cellularity ... extranodal and solid organ sites
  • C81.3 - Lymphocyte depleted Hodgkin lymphoma
  • C81.30 - Lymphocyte depleted ... unspecified site
  • C81.31 - Lymphocyte depleted ... lymph nodes of head, face, and neck
  • C81.32 - Lymphocyte depleted ... intrathoracic lymph nodes
  • C81.33 - Lymphocyte depleted ... intra-abdominal lymph nodes
  • C81.34 - Lymphocyte depleted ... lymph nodes of axilla and upper limb
  • C81.35 - Lymphocyte depleted ... lymph nodes of inguinal region and lower limb
  • C81.36 - Lymphocyte depleted ... intrapelvic lymph nodes
  • C81.37 - Lymphocyte depleted ... spleen
  • C81.38 - Lymphocyte depleted ... lymph nodes of multiple sites
  • C81.39 - Lymphocyte depleted ... extranodal and solid organ sites
  • C81.4 - Lymphocyte-rich Hodgkin lymphoma
  • C81.40 - Lymphocyte-rich ... unspecified site
  • C81.41 - Lymphocyte-rich ... lymph nodes of head, face, and neck
  • C81.42 - Lymphocyte-rich ... intrathoracic lymph nodes
  • C81.43 - Lymphocyte-rich ... intra-abdominal lymph nodes
  • C81.44 - Lymphocyte-rich ... lymph nodes of axilla and upper limb
  • C81.45 - Lymphocyte-rich ... lymph nodes of inguinal region and lower limb
  • C81.46 - Lymphocyte-rich ... intrapelvic lymph nodes
  • C81.47 - Lymphocyte-rich ... spleen
  • C81.48 - Lymphocyte-rich ... lymph nodes of multiple sites
  • C81.49 - Lymphocyte-rich ... extranodal and solid organ sites
  • C81.7 - Other Hodgkin lymphoma
  • C81.70 - Other ... unspecified site
  • C81.71 - Other ... lymph nodes of head, face, and neck
  • C81.72 - Other ... intrathoracic lymph nodes
  • C81.73 - Other ... intra-abdominal lymph nodes
  • C81.74 - Other ... lymph nodes of axilla and upper limb
  • C81.75 - Other ... lymph nodes of inguinal region and lower limb
  • C81.76 - Other ... intrapelvic lymph nodes
  • C81.77 - Other ... spleen
  • C81.78 - Other ... lymph nodes of multiple sites
  • C81.79 - Other ... extranodal and solid organ sites
  • C81.9 - ... unspecified
  • C81.90 - ... unspecified, unspecified site
  • C81.91 - ... unspecified, lymph nodes of head, face, and neck
  • C81.92 - ... unspecified, intrathoracic lymph nodes
  • C81.93 - ... unspecified, intra-abdominal lymph nodes
  • C81.94 - ... unspecified, lymph nodes of axilla and upper limb
  • C81.95 - ... unspecified, lymph nodes of inguinal region and lower limb
  • C81.96 - ... unspecified, intrapelvic lymph nodes
  • C81.97 - ... unspecified, spleen
  • C81.98 - ... unspecified, lymph nodes of multiple sites
  • C81.99 - ... unspecified, extranodal and solid organ sites

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code C81:

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • personal history of Hodgkin lymphoma Z85.71

Clinical Information

  • HODGKIN DISEASE-. a malignant disease characterized by progressive enlargement of the lymph nodes spleen and general lymphoid tissue. in the classical variant giant usually multinucleate hodgkin's and reed sternberg cells are present; in the nodular lymphocyte predominant variant lymphocytic and histiocytic cells are seen.

Code Classification

  • Neoplasms (C00–D48)
    • Malignant neoplasms of lymphoid, hematopoietic and related tissue (C81-C96)
      • Hodgkin lymphoma (C81)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Hodgkin Disease

Hodgkin disease is a type of lymphoma. Lymphoma is a cancer of a part of the immune system called the lymph system. The first sign of Hodgkin disease is often an enlarged lymph node. The disease can spread to nearby lymph nodes. Later it may spread to the lungs, liver, or bone marrow. The exact cause is unknown.

Hodgkin disease is rare. Symptoms include

  • Painless swelling of the lymph nodes in the neck, armpits, or groin
  • Fever and chills
  • Night sweats
  • Weight loss
  • Loss of appetite
  • Itchy skin

To diagnose Hodgkin disease, doctors use a physical exam and history, blood tests, and a biopsy. Treatment depends on how far the disease has spread. It often includes radiation therapy or chemotherapy.

The earlier the disease is diagnosed, the more effective the treatment. In most cases, Hodgkin disease can be cured.

NIH: National Cancer Institute


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