Version 2024

2024 ICD-10-CM Diagnosis Code C49

Malignant neoplasm of other connective and soft tissue

ICD-10-CM Code:
C49
ICD-10 Code for:
Malignant neoplasm of other connective and soft tissue
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Neoplasms
    (C00–D49)
    • Malignant neoplasms of mesothelial and soft tissue
      (C45-C49)
      • Malignant neoplasm of other connective and soft tissue
        (C49)

C49 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of malignant neoplasm of other connective and soft tissue. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Malignant neoplasm of other connective and soft tissue

Non-specific codes like C49 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for malignant neoplasm of other connective and soft tissue:

  • Use C49.0 for Malignant neoplasm of connective and soft tissue of head, face and neck - BILLABLE CODE

  • C49.1 for Malignant neoplasm of connective and soft tissue of upper limb, including shoulder - NON-BILLABLE CODE

  • Use C49.10 for Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder - BILLABLE CODE

  • Use C49.11 for Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder - BILLABLE CODE

  • Use C49.12 for Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder - BILLABLE CODE

  • C49.2 for Malignant neoplasm of connective and soft tissue of lower limb, including hip - NON-BILLABLE CODE

  • Use C49.20 for Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip - BILLABLE CODE

  • Use C49.21 for Malignant neoplasm of connective and soft tissue of right lower limb, including hip - BILLABLE CODE

  • Use C49.22 for Malignant neoplasm of connective and soft tissue of left lower limb, including hip - BILLABLE CODE

  • Use C49.3 for Malignant neoplasm of connective and soft tissue of thorax - BILLABLE CODE

  • Use C49.4 for Malignant neoplasm of connective and soft tissue of abdomen - BILLABLE CODE

  • Use C49.5 for Malignant neoplasm of connective and soft tissue of pelvis - BILLABLE CODE

  • Use C49.6 for Malignant neoplasm of connective and soft tissue of trunk, unspecified - BILLABLE CODE

  • Use C49.8 for Malignant neoplasm of overlapping sites of connective and soft tissue - BILLABLE CODE

  • Use C49.9 for Malignant neoplasm of connective and soft tissue, unspecified - BILLABLE CODE

  • C49.A for Gastrointestinal stromal tumor - NON-BILLABLE CODE

  • Use C49.A0 for Gastrointestinal stromal tumor, unspecified site - BILLABLE CODE

  • Use C49.A1 for Gastrointestinal stromal tumor of esophagus - BILLABLE CODE

  • Use C49.A2 for Gastrointestinal stromal tumor of stomach - BILLABLE CODE

  • Use C49.A3 for Gastrointestinal stromal tumor of small intestine - BILLABLE CODE

  • Use C49.A4 for Gastrointestinal stromal tumor of large intestine - BILLABLE CODE

  • Use C49.A5 for Gastrointestinal stromal tumor of rectum - BILLABLE CODE

  • Use C49.A9 for Gastrointestinal stromal tumor of other sites - BILLABLE CODE

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Includes

Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • malignant neoplasm of cartilage (of):
  • articular C40 C41
  • larynx C32.3
  • nose C30.0
  • malignant neoplasm of connective tissue of breast C50

Type 2 Excludes

Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
  • Kaposi's sarcoma of soft tissue C46.1
  • malignant neoplasm of heart C38.0
  • malignant neoplasm of peripheral nerves and autonomic nervous system C47
  • malignant neoplasm of peritoneum C48.2
  • malignant neoplasm of retroperitoneum C48.0
  • malignant neoplasm of uterine ligament C57.3
  • mesothelioma C45

Patient Education


Cancer

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, immunotherapy or other types of biologic therapy, or stem cell transplantation.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


[Learn More in MedlinePlus]

Soft Tissue Sarcoma-Patient Version

Learn about soft tissue sarcoma risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.