2024 ICD-10-CM Diagnosis Code C25.4
Malignant neoplasm of endocrine pancreas
- ICD-10-CM Code:
- C25.4
- ICD-10 Code for:
- Malignant neoplasm of endocrine pancreas
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Chronic
- Code Navigator:
C25.4 is a billable diagnosis code used to specify a medical diagnosis of malignant neoplasm of endocrine pancreas. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.
The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic insular tissue (pancreas) or Neoplasm, neoplastic islands or islets of Langerhans or Neoplasm, neoplastic Langerhans, islands or islets or Neoplasm, neoplastic pancreas islet cells .
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Carcinoma of endocrine pancreas
- Hyperinsulinemia due to malignant insulinoma
- Malignant gastrinoma of pancreas
- Malignant glucagonoma of pancreas
- Malignant insulinoma
- Malignant tumor of endocrine pancreas
- Malignant tumor of Islets of Langerhans
- Primary carcinoma of endocrine pancreas
- Primary carcinoma of pancreas
- Primary malignant gastrinoma of pancreas
- Primary malignant glucagonoma of pancreas
- Primary malignant insulinoma
- Primary malignant neoplasm of islets of Langerhans
Clinical Classification
Clinical Category is Endocrine system cancers - pancreas
- CCSR Category Code: NEO051
- Inpatient Default CCSR: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
- Outpatient Default CCSR: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Tabular List of Diseases and Injuries
The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Malignant neoplasm of islets of Langerhans
Use Additional Code
Use Additional CodeThe “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
- code to identify any functional activity.
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Adenocarcinoma - See Also: Neoplasm, malignant, by site;
- - islet cell
- - pancreas - C25.4
- - unspecified site - C25.4
- - islet cell
- - Carcinoma (malignant) - See Also: Neoplasm, by site, malignant;
- - islet cell
- - pancreas - C25.4
- - unspecified site - C25.4
- - islet cell
- - Gastrinoma
- - malignant
- - pancreas - C25.4
- - unspecified site - C25.4
- - malignant
- - Glucagonoma
- - pancreas
- - malignant - C25.4
- - unspecified site
- - malignant - C25.4
- - pancreas
- - Insulinoma
- - pancreas
- - malignant - C25.4
- - unspecified site
- - malignant - C25.4
- - pancreas
- - Tumor - See Also: Neoplasm, unspecified behavior, by site;
- - alpha-cell
- - malignant
- - pancreas - C25.4
- - unspecified site - C25.4
- - malignant
- - beta-cell
- - malignant
- - pancreas - C25.4
- - unspecified site - C25.4
- - malignant
- - G cell
- - malignant
- - pancreas - C25.4
- - unspecified site - C25.4
- - malignant
- - islet cell - See: Neoplasm, benign, by site;
- - malignant - See: Neoplasm, malignant, by site;
- - pancreas - C25.4
- - unspecified site - C25.4
- - malignant - See: Neoplasm, malignant, by site;
- - alpha-cell
Convert C25.4 to ICD-9-CM
- ICD-9-CM Code: 157.4 - Mal neo islet langerhans
Table of Neoplasms
This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.
Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.
Neoplasm, neoplastic | Malignant Primary |
Malignant Secondary |
CaInSitu | Benign | Uncertain Behavior |
Unspecified Behavior |
---|---|---|---|---|---|---|
»Neoplasm, neoplastic »insular tissue (pancreas) | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
»Neoplasm, neoplastic »islands or islets of Langerhans | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
»Neoplasm, neoplastic »Langerhans, islands or islets | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
»Neoplasm, neoplastic »pancreas »islet cells | C25.4 | C78.89 | D01.7 | D13.7 | D37.8 | D49.0 |
Patient Education
Pancreatic Cancer
The pancreas is a gland behind your stomach and in front of your spine. It produces the juices that help break down food and the hormones that help control blood sugar levels. Pancreatic cancer usually begins in the cells that produce the juices. Some risk factors for developing pancreatic cancer include:
- Smoking
- Long-term diabetes
- Chronic pancreatitis
- Certain hereditary disorders
Pancreatic cancer is hard to catch early. It doesn't cause symptoms right away. When you do get symptoms, they are often vague or you may not notice them. They include yellowing of the skin and eyes, pain in the abdomen and back, weight loss and fatigue. Also, because the pancreas is hidden behind other organs, health care providers cannot see or feel the tumors during routine exams. Doctors use a physical exam, blood tests, imaging tests, and a biopsy to diagnose it.
Because it is often found late and it spreads quickly, pancreatic cancer can be hard to treat. Possible treatments include surgery, radiation, chemotherapy, and targeted therapy. Targeted therapy uses drugs or other substances that attack specific cancer cells with less harm to normal cells.
NIH: National Cancer Institute
[Learn More in MedlinePlus]
Pancreatic Cancer-Patient Version
Learn about pancreatic cancer risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.[Learn More in MedlinePlus]
Pancreatic Cancer Summary
Learn about pancreatic cancer risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.[Learn More in MedlinePlus]
Pancreatic Neuroendocrine Tumors (Islet Cell Tumors) Treatment (PDQ®)
Learn about pancreatic neuroendocrine tumor (islet cell tumor) risk factors, signs and symptoms, tests to diagnose, factors affecting prognosis, and treatment.[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.