2027 ICD-10-CM Diagnosis Code D89Other disorders involving the immune mechanism, not elsewhere classified
D89 is a non-billable ICD-10-CM category code for other disorders involving the immune mechanism, not elsewhere classified, so it cannot be submitted on claims. Use a more specific code from this category instead, such as D89.0, D89.1, D89.2, and D89.3.
Code Identity
Code Classification
Specific Coding for Oth disorders involving the immune mechanism, NECOverview
Non-specific codes like D89 require more characters. Use one of these billable codes instead:
Use D89.0 for Polyclonal hypergammaglobulinemia
Use D89.1 for Cryoglobulinemia
Use D89.2 for Hypergammaglobulinemia, unspecified
Use D89.3 for Immune reconstitution syndrome
D89.4 for Mast cell activation syndrome and related disorders
Use D89.40 for Mast cell activation, unspecified
Use D89.41 for Monoclonal mast cell activation syndrome
Use D89.42 for Idiopathic mast cell activation syndrome
Use D89.43 for Secondary mast cell activation
Use D89.44 for Hereditary alpha tryptasemia
Use D89.49 for Other mast cell activation disorder
D89.8 for Other specified disorders involving the immune mechanism, not elsewhere classified
D89.81 for Graft-versus-host disease
Use D89.82 for Autoimmune lymphoproliferative syndrome [ALPS]
D89.83 for Cytokine release syndrome
Use D89.84 for IgG4-related disease
Use D89.89 for Other specified disorders involving the immune mechanism, not elsewhere classified
Use D89.9 for Disorder involving the immune mechanism, unspecified
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to D89: its own notes plus those printed at block D80-D89 and Chapter 3. A note printed at a category, block or chapter applies to every code under it.
Includes
Further defines, or gives examples of, the content of the category.
- defects in the complement system
- immunodeficiency disorders, except human immunodeficiency virus [HIV] disease
- sarcoidosis
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- transplant failure and rejection (T86.-)
- human immunodeficiency virus [HIV] disease (B20)
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name D89, its category, or a range that includes it.
Patient EducationClinical
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.
The full article covers:
- What is the immune system?
- What are the parts of the immune system?
- How does the immune system work?
- What are the types of immunity?
- What can go wrong with the immune system?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code HistoryHistory
Questions About D89Overview
Is D89 a billable code?
No. This is a category header that groups the codes for other disorders involving the immune mechanism, not elsewhere classified, and headers cannot be submitted on claims. Claims for other disorders involving the immune mechanism, not elsewhere classified need a more specific code from this category, such as D89.0, D89.1, and D89.2.
Can D89 be reported with R77.1?
Not as a rule. The Excludes1 note on D89 lists "hyperglobulinemia NOS (R77.1)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
