2026 ICD-10-CM Diagnosis Code D89Other disorders involving the immune mechanism, not elsewhere classified
D89 is a non-billable ICD-10-CM category code for other disorders involving the immune mechanism, not elsewhere classified, so it cannot be submitted on claims. Use a more specific code from this category instead, such as D89.0, D89.1, D89.2, and D89.3.
Code Identity
Code Classification
Specific Coding for Oth disorders involving the immune mechanism, NECOverview
Non-specific codes like D89 require more characters. Use one of these billable codes instead:
Use D89.0 for Polyclonal hypergammaglobulinemia
Use D89.1 for Cryoglobulinemia
Use D89.2 for Hypergammaglobulinemia, unspecified
Use D89.3 for Immune reconstitution syndrome
D89.4 for Mast cell activation syndrome and related disorders
Use D89.40 for Mast cell activation, unspecified
Use D89.41 for Monoclonal mast cell activation syndrome
Use D89.42 for Idiopathic mast cell activation syndrome
Use D89.43 for Secondary mast cell activation
Use D89.44 for Hereditary alpha tryptasemia
Use D89.49 for Other mast cell activation disorder
D89.8 for Other specified disorders involving the immune mechanism, not elsewhere classified
D89.81 for Graft-versus-host disease
Use D89.82 for Autoimmune lymphoproliferative syndrome [ALPS]
D89.83 for Cytokine release syndrome
Use D89.84 for IgG4-related disease
Use D89.89 for Other specified disorders involving the immune mechanism, not elsewhere classified
Use D89.9 for Disorder involving the immune mechanism, unspecified
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Type 1 Excludes
Type 2 Excludes
- transplant failure and rejection T86
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Patient EducationClinical
Immune System and Disorders
Your immune system is a complex network of cells, tissues, and organs. Together they help the body fight infections and other diseases.
The full article covers:
- What is the immune system?
- What are the parts of the immune system?
- How does the immune system work?
- What are the types of immunity?
- What can go wrong with the immune system?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code HistoryHistory
Questions About D89Overview
Is D89 a billable code?
No. This is a category header that groups the codes for other disorders involving the immune mechanism, not elsewhere classified, and headers cannot be submitted on claims. Claims for other disorders involving the immune mechanism, not elsewhere classified need a more specific code from this category, such as D89.0, D89.1, and D89.2.
