2024 ICD-10-CM Diagnosis Code C49.3

Malignant neoplasm of connective and soft tissue of thorax

ICD-10-CM Code:
C49.3
ICD-10 Code for:
Malignant neoplasm of connective and soft tissue of thorax
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Neoplasms
    (C00–D49)
    • Malignant neoplasms of mesothelial and soft tissue
      (C45-C49)
      • Malignant neoplasm of other connective and soft tissue
        (C49)

C49.3 is a billable diagnosis code used to specify a medical diagnosis of malignant neoplasm of connective and soft tissue of thorax. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

The following anatomical sites found in the Table of Neoplasms reference this diagnosis code given the correct histological behavior: Neoplasm, neoplastic aorta (thoracic) ; Neoplasm, neoplastic connective tissue NEC axilla ; Neoplasm, neoplastic connective tissue NEC chest (wall) ; Neoplasm, neoplastic connective tissue NEC diaphragm ; Neoplasm, neoplastic connective tissue NEC great vessels NEC ; Neoplasm, neoplastic connective tissue NEC infraclavicular region ; Neoplasm, neoplastic connective tissue NEC intrathoracic ; etc

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Leiomyosarcoma of esophagus
  • Leiomyosarcoma of lower esophagus
  • Malignant mesenchymal neoplasm of esophagus
  • Malignant tumor of soft tissue of thorax
  • Malignant tumor of thoracic part of esophagus
  • Neoplasm of blood vessel of axilla
  • Neoplasm of blood vessel of shoulder
  • Neoplasm of blood vessel of thorax
  • Neoplasm of diaphragm
  • Neoplasm of great vessels
  • Neoplasm of muscle of abdomen
  • Neoplasm of muscle of thorax
  • Neoplasm of muscle of thorax
  • Primary angiosarcoma of axillary region
  • Primary angiosarcoma of thorax
  • Primary angiosarcoma of trunk
  • Primary leiomyosarcoma of thorax
  • Primary liposarcoma of soft tissue of axilla
  • Primary liposarcoma of soft tissue of limb
  • Primary liposarcoma of soft tissue of thorax
  • Primary liposarcoma of soft tissue of trunk
  • Primary malignant neoplasm of axilla
  • Primary malignant neoplasm of axilla
  • Primary malignant neoplasm of axilla
  • Primary malignant neoplasm of axilla
  • Primary malignant neoplasm of blood vessel of axilla
  • Primary malignant neoplasm of blood vessel of shoulder
  • Primary malignant neoplasm of blood vessel of thorax
  • Primary malignant neoplasm of blood vessel of trunk
  • Primary malignant neoplasm of blood vessel of upper limb
  • Primary malignant neoplasm of diaphragm
  • Primary malignant neoplasm of great vessels
  • Primary malignant neoplasm of muscle of abdomen
  • Primary malignant neoplasm of muscle of thorax
  • Primary malignant neoplasm of muscle of trunk
  • Primary malignant neoplasm of muscle of trunk
  • Primary malignant neoplasm of soft tissues of axilla
  • Primary malignant neoplasm of soft tissues of thorax
  • Primary rhabdomyosarcoma of thorax
  • Primary sarcoma of axilla
  • Primary sarcoma of axilla
  • Primary sarcoma of thorax
  • SMARCA4-deficient undifferentiated neoplasm of thorax

Clinical Classification

Clinical Information

  • Contraceptive Devices, Female

    contraceptive devices used by females.
  • Diaphragm

    the musculofibrous partition that separates the thoracic cavity from the abdominal cavity. contraction of the diaphragm increases the volume of the thoracic cavity aiding inhalation.
  • Diaphragmatic Eventration

    a congenital abnormality characterized by the elevation of the diaphragm dome. it is the result of a thinned diaphragmatic muscle and injured phrenic nerve, allowing the intra-abdominal viscera to push the diaphragm upward against the lung.
  • Hernia, Diaphragmatic

    protrusion of abdominal structures into the thorax as a result of congenital or traumatic defects in the respiratory diaphragm.
  • Hernia, Diaphragmatic, Traumatic

    the type of diaphragmatic hernia caused by trauma or injury, usually to the abdomen.
  • Hernias, Diaphragmatic, Congenital

    protrusion of abdominal structures into the thorax as a result of embryologic defects in the diaphragm often present in the neonatal period. it can be isolated, syndromic, non-syndromic or be a part of chromosome abnormality. associated pulmonary hypoplasia and pulmonary hypertension can further complicate stabilization and surgical intervention.
  • Inferior Wall Myocardial Infarction

    myocardial infarction in which the inferior wall of the heart is involved. it is often caused by occlusion of the right coronary artery.
  • Pelvic Floor

    soft tissue formed mainly by the pelvic diaphragm, which is composed of the two levator ani and two coccygeus muscles. the pelvic diaphragm lies just below the pelvic aperture (outlet) and separates the pelvic cavity from the perineum. it extends between the pubic bone anteriorly and the coccyx posteriorly.
  • Peritoneal Stomata

    natural openings in the subdiaphragmatic lymphatic plexus in the peritoneum, delimited by adjacent mesothelial cells. peritoneal stomata constitute the principal pathways for the drainage of intraperitoneal contents from the peritoneal cavity to the lymphatic system.
  • Respiratory Paralysis

    complete or severe weakness of the muscles of respiration. this condition may be associated with motor neuron diseases; peripheral nerve diseases; neuromuscular junction diseases; spinal cord diseases; injury to the phrenic nerve; and other disorders.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Malignant neoplasm of axilla
  • Malignant neoplasm of diaphragm
  • Malignant neoplasm of great vessels

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • malignant neoplasm of breast C50
  • malignant neoplasm of heart C38.0
  • malignant neoplasm of mediastinum C38.1 C38.3
  • malignant neoplasm of thymus C37

Convert C49.3 to ICD-9-CM

  • ICD-9-CM Code: 171.4 - Mal neo soft tis thorax
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Table of Neoplasms

This code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »aorta (thoracic)
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »axilla
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »chest (wall)
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »diaphragm
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »great vessels NEC
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »infraclavicular region
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »intrathoracic
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »scapular region
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »thoracic (duct) (wall)
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »connective tissue NEC
    »thorax
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »diaphragm
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »great vessels NEC
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »thorax, thoracic (cavity) (organs NEC)
    »duct
C49.3C79.89 D21.3D48.1D49.2
»Neoplasm, neoplastic
  »vena cava (abdominal) (inferior)
    »superior
C49.3C79.89 D21.3D48.1D49.2

Patient Education


Cancer

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, immunotherapy or other types of biologic therapy, or stem cell transplantation.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Connective Tissue Disorders

Your connective tissue supports many different parts of your body, such as your skin, eyes, and heart. It is like a "cellular glue" that gives your body parts their shape and helps keep them strong. It also helps some of your tissues do their work. It is made of many kinds of proteins. Cartilage and fat are types of connective tissue.

Over 200 disorders that impact connective tissue. There are different types:

  • Genetic disorders, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta
  • Autoimmune disorders, such as lupus and scleroderma
  • Cancers, like some types of soft tissue sarcoma

Each disorder has its own symptoms and needs different treatment.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases


[Learn More in MedlinePlus]

Soft Tissue Sarcoma-Patient Version

Learn about soft tissue sarcoma risk factors, symptoms, tests to diagnose, factors affecting prognosis, staging, and treatment.
[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.