ICD-10-CM Code N42.31

Prostatic intraepithelial neoplasia

Version 2020 Billable Code Diagnoses For Males Only

Valid for Submission

N42.31 is a billable code used to specify a medical diagnosis of prostatic intraepithelial neoplasia. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code N42.31 might also be used to specify conditions or terms like carcinoma in situ of prostate or low grade prostatic intraepithelial neoplasia or prostatic intraepithelial neoplasia or prostatic intraepithelial neoplasia low grade.

The code N42.31 is applicable to male patients only. It is clinically and virtually impossible to use this code on a non-male patient.

Short Description:Prostatic intraepithelial neoplasia
Long Description:Prostatic intraepithelial neoplasia

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code N42.31:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • PIN
  • Prostatic intraepithelial neoplasia I (PIN I)
  • Prostatic intraepithelial neoplasia II (PIN II)

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • prostatic intraepithelial neoplasia III PIN III D07.5

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code N42.31 are found in the index:

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10 Code Edits are applicable to this code:

  • Diagnoses for males only - Medicare Code Editor detects inconsistencies between a patient’s sex and any diagnosis on the patient’s record, this code applies to MALES only .


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Carcinoma in situ of prostate
  • Low grade prostatic intraepithelial neoplasia
  • Prostatic intraepithelial neoplasia
  • Prostatic intraepithelial neoplasia low grade

Clinical Information

  • PROSTATIC INTRAEPITHELIAL NEOPLASIA-. a premalignant change arising in the prostatic epithelium regarded as the most important and most likely precursor of prostatic adenocarcinoma. the neoplasia takes the form of an intra acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia which corresponds to nuclear grade 2 and 3 invasive prostate cancer.

Diagnostic Related Groups

The ICD-10 code N42.31 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2019 through 09/30/2020.


Replacement Code

N4231 replaces the following previously assigned ICD-10 code(s):

  • N42.3 - Dysplasia of prostate

Convert N42.31 to ICD-9

  • 602.3 - Dysplasia of prostate (Approximate Flag)

Code Classification

  • Diseases of the genitourinary system (N00–N99)
    • Diseases of male genital organs (N40-N53)
      • Other and unspecified disorders of prostate (N42)

Code History

  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020