2022 ICD-10-CM Code D89.4

Mast cell activation syndrome and related disorders

Version 2021

Not Valid for Submission

ICD-10:D89.4
Short Description:Mast cell activation syndrome and related disorders
Long Description:Mast cell activation syndrome and related disorders

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Certain disorders involving the immune mechanism (D80-D89)
      • Oth disorders involving the immune mechanism, NEC (D89)

D89.4 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of mast cell activation syndrome and related disorders. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding for Mast cell activation syndrome and related disorders

Non-specific codes like D89.4 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for mast cell activation syndrome and related disorders:

  • BILLABLE CODE - Use D89.40 for Mast cell activation, unspecified
  • BILLABLE CODE - Use D89.41 for Monoclonal mast cell activation syndrome
  • BILLABLE CODE - Use D89.42 for Idiopathic mast cell activation syndrome
  • BILLABLE CODE - Use D89.43 for Secondary mast cell activation
  • BILLABLE CODE - Use D89.44 for Hereditary alpha tryptasemia
  • BILLABLE CODE - Use D89.49 for Other mast cell activation disorder

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D89.4:


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018