ICD-10-CM Code D64.4

Congenital dyserythropoietic anemia

Version 2020 Billable Code

Valid for Submission

D64.4 is a billable code used to specify a medical diagnosis of congenital dyserythropoietic anemia. The code is valid for the year 2020 for the submission of HIPAA-covered transactions. The ICD-10-CM code D64.4 might also be used to specify conditions or terms like congenital dyserythropoietic anemia, congenital dyserythropoietic anemia, congenital dyserythropoietic anemia type iv, congenital dyserythropoietic anemia, type i, congenital dyserythropoietic anemia, type ii, congenital dyserythropoietic anemia, type iii, etc

ICD-10:D64.4
Short Description:Congenital dyserythropoietic anemia
Long Description:Congenital dyserythropoietic anemia

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code D64.4:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Dyshematopoietic anemia (congenital)

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Blackfan-Diamond syndrome D61.01
  • Di Guglielmo's disease C94.0

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D64.4 are found in the index:


Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Congenital dyserythropoietic anemia
  • Congenital dyserythropoietic anemia
  • Congenital dyserythropoietic anemia type IV
  • Congenital dyserythropoietic anemia, type I
  • Congenital dyserythropoietic anemia, type II
  • Congenital dyserythropoietic anemia, type III
  • Cytochrome-c oxidase deficiency
  • Exocrine pancreatic insufficiency
  • GATA binding protein 1 related thrombocytopenia with dyserythropoiesis
  • Pancreatic insufficiency
  • Pancreatic insufficiency, dyserythropoietic anemia, calvarial hyperostosis syndrome
  • X-linked congenital dyserythropoietic anemia with thrombocytopenia

Clinical Information

  • ANEMIA DYSERYTHROPOIETIC CONGENITAL-. a familial disorder characterized by anemia with multinuclear erythroblasts karyorrhexis asynchrony of nuclear and cytoplasmic maturation and various nuclear abnormalities of bone marrow erythrocyte precursors erythroid precursor cells. type ii is the most common of the 3 types; it is often referred to as hempas based on the hereditary erythroblast multinuclearity with positive acidified serum test.

Diagnostic Related Groups

The ICD-10 code D64.4 is grouped in the following groups for version MS-DRG V37.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2020.

  • 811 - RED BLOOD CELL DISORDERS WITH MCC
  • 812 - RED BLOOD CELL DISORDERS WITHOUT MCC

Convert D64.4 to ICD-9

  • 285.8 - Anemia NEC (Approximate Flag)

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Aplastic and other anemias and other bone marrow failure syndromes (D60-D64)
      • Other anemias (D64)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Anemia

If you have anemia, your blood does not carry enough oxygen to the rest of your body. The most common cause of anemia is not having enough iron. Your body needs iron to make hemoglobin. Hemoglobin is an iron-rich protein that gives the red color to blood. It carries oxygen from the lungs to the rest of the body.

Anemia has three main causes: blood loss, lack of red blood cell production, and high rates of red blood cell destruction.

Conditions that may lead to anemia include

  • Heavy periods
  • Pregnancy
  • Ulcers
  • Colon polyps or colon cancer
  • Inherited disorders
  • A diet that does not have enough iron, folic acid or vitamin B12
  • Blood disorders such as sickle cell anemia and thalassemia, or cancer
  • Aplastic anemia, a condition that can be inherited or acquired
  • G6PD deficiency, a metabolic disorder

Anemia can make you feel tired, cold, dizzy, and irritable. You may be short of breath or have a headache.

Your doctor will diagnose anemia with a physical exam and blood tests. Treatment depends on the kind of anemia you have.

NIH: National Heart, Lung, and Blood Institute


[Learn More]

Congenital dyserythropoietic anemia Congenital dyserythropoietic anemia (CDA) is an inherited blood disorder that affects the development of red blood cells. This disorder is one of many types of anemia, which is a condition characterized by a shortage of red blood cells. This shortage prevents the blood from carrying an adequate supply of oxygen to the body's tissues. The resulting symptoms can include tiredness (fatigue), weakness, pale skin, and other complications.Researchers have identified three major types of CDA: type I, type II, and type III. The types have different genetic causes and different but overlapping patterns of signs and symptoms.CDA type I is characterized by moderate to severe anemia. It is usually diagnosed in childhood or adolescence, although in some cases, the condition can be detected before birth. Many affected individuals have yellowing of the skin and eyes (jaundice) and an enlarged liver and spleen (hepatosplenomegaly). This condition also causes the body to absorb too much iron, which builds up and can damage tissues and organs. In particular, iron overload can lead to an abnormal heart rhythm (arrhythmia), congestive heart failure, diabetes, and chronic liver disease (cirrhosis). Rarely, people with CDA type I are born with skeletal abnormalities, most often involving the fingers and/or toes.The anemia associated with CDA type II can range from mild to severe, and most affected individuals have jaundice, hepatosplenomegaly, and the formation of hard deposits in the gallbladder called gallstones. This form of the disorder is usually diagnosed in adolescence or early adulthood. An abnormal buildup of iron typically occurs after age 20, leading to complications including heart disease, diabetes, and cirrhosis.The signs and symptoms of CDA type III tend to be milder than those of the other types. Most affected individuals do not have hepatosplenomegaly, and iron does not build up in tissues and organs. In adulthood, abnormalities of a specialized tissue at the back of the eye (the retina) can cause vision impairment. Some people with CDA type III also have a blood disorder known as monoclonal gammopathy, which can lead to a cancer of white blood cells (multiple myeloma).Several other variants of CDA have been described, although they appear to be rare and not much is known about them. Once researchers discover the genetic causes of these variants, some of them may be grouped with the three major types of CDA.
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