Metabolic disorders (E70-E88) ICD-10-CM
The E70–E88 section covers metabolic disorders with 366 ICD-10-CM diagnosis codes, of which 286 are billable in fiscal year 2026. The section is organized into the 17 code ranges listed below.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- androgen insensitivity syndrome E34.5
- congenital adrenal hyperplasia E25.0
- hemolytic anemias attributable to enzyme disorders D55
- Marfan syndrome Q87.4
- 5-alpha-reductase deficiency E29.1
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
- Ehlers-Danlos syndromes Q79.6
Code Ranges in This Section 17 ranges · 366 codes
The info icon previews the code ranges inside each row and its instructional notations from the official Tabular List.
About the E70–E88 Code Range
ICD-10 codes E70-E88 cover a wide range of metabolic disorders, including inherited and acquired conditions affecting amino acid, carbohydrate, lipid, and mineral metabolism. These codes are used to document specific metabolic diseases such as phenylketonuria (E70.0), lipid storage disorders (E75), glycogen storage diseases (E74.0-E74.09), and disorders of fluid and electrolyte balance (E87).
This code range includes disorders of aromatic amino-acid metabolism like phenylketonuria, tyrosinemia, and albinism (E70 series), with synonyms guiding coders to associate common names such as classical phenylketonuria and ocular albinism with their precise codes. Branched-chain amino acid and fatty-acid metabolism disorders (E71) cover conditions like maple syrup urine disease and medium chain acyl CoA dehydrogenase deficiency. Carbohydrate metabolism disorders (E73-E74), including various forms of lactose intolerance and glycogen storage diseases, are specified for accurate coding. Lipid metabolism codes (E75-E78) identify complex disorders such as Fabry disease and familial hypercholesterolemia. The codes also address mineral metabolism abnormalities (E83), cystic fibrosis (E84), amyloidosis types (E85), and fluid/electrolyte imbalances (E86-E87), reflecting conditions like dehydration, hypokalemia, and hypernatremia. Finally, E88 captures other unspecified metabolic disorders, including mitochondrial diseases and lipodystrophies, aiding precise documentation of diverse metabolic conditions.
Questions About This Page
How many codes are in the E70-E88 range?
The E70-E88 range contains 366 ICD-10-CM diagnosis codes in FY 2026. 286 of them are billable, and the rest are category headers that organize the section.
What conditions does E70-E88 cover?
The range covers metabolic disorders. The code ranges listed above break it into groups of related conditions, and each one links to its own page with the full code list.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
