ICD-10-CM Code E72.8

Other specified disorders of amino-acid metabolism

Version 2020 Replaced Code Non-Billable Code

Not Valid for Submission

E72.8 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of other specified disorders of amino-acid metabolism. The code is NOT valid for the year 2020 for the submission of HIPAA-covered transactions.

ICD-10:E72.8
Short Description:Other specified disorders of amino-acid metabolism
Long Description:Other specified disorders of amino-acid metabolism

Consider the following ICD-10 codes with a higher level of specificity:

  • E72.81 - Disorders of gamma aminobutyric acid metabolism
  • E72.89 - Other specified disorders of amino-acid metabolism

Replaced Code

This code was replaced in the 2020 ICD-10 code set with the code(s) listed below. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2019. This code was replaced for the FY 2020 (October 1, 2019 - September 30, 2020).

  • E72.81 - Disorders of gamma aminobutyric acid metabolism
  • E72.89 - Other specified disorders of amino-acid metabolism

Convert E72.8 to ICD-9

  • 270.7 - Straig amin-acid met NEC (Approximate Flag)
  • 270.8 - Dis amino-acid metab NEC (Approximate Flag)

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Metabolic disorders (E70-E88)
      • Other disorders of amino-acid metabolism (E72)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - Code Deleted, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020

Information for Patients


Amino Acid Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Your digestive system breaks the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body. If you have a metabolic disorder, something goes wrong with this process.

One group of these disorders is amino acid metabolism disorders. They include phenylketonuria (PKU) and maple syrup urine disease. Amino acids are "building blocks" that join together to form proteins. If you have one of these disorders, your body may have trouble breaking down certain amino acids. Or there may be a problem getting the amino acids into your cells. These problems cause a buildup of harmful substances in your body. That can lead to serious, sometimes life-threatening, health problems.

These disorders are usually inherited. A baby who is born with one may not have any symptoms right away. Because the disorders can be so serious, early diagnosis and treatment are critical. Newborn babies get screened for many of them, using blood tests.

Treatments may include special diets, medicines, and supplements. Some babies may also need additional treatments if there are complications.


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