Cystic fibrosis (E84)
ICD-10 code E84 identifies cystic fibrosis, a genetic disorder chiefly affecting the lungs and digestive system. These codes help specify the particular complications or manifestations of cystic fibrosis to guide accurate medical diagnosis and treatment.
The ICD-10 code for cystic fibrosis (E84) includes various subcodes that reflect its complex nature. For instance, E84.0 is used when cystic fibrosis involves the lungs, also known as cystic fibrosis of the lung. Digestive complications are captured under E84.1, with further detail such as E84.11 for meconium ileus, a form of perinatal intestinal obstruction linked to cystic fibrosis. The code E84.19 covers other intestinal issues like distal intestinal obstruction syndrome. Additionally, E84.8 encompasses other manifestations including liver disease, pancreatic insufficiency, and infertility related to cystic fibrosis. When the diagnosis is less specific, E84.9 applies, covering variants such as classical, atypical, or subclinical cystic fibrosis. These detailed codes assist clinicians and coders in pinpointing the exact cystic fibrosis condition present for accurate health records and treatment planning.
Endocrine, nutritional and metabolic diseases (E00–E89)
Metabolic disorders (E70-E88)
E84 Cystic fibrosis
- E84.0 Cystic fibrosis with pulmonary manifestations
E84.1 Cystic fibrosis with intestinal manifestations
- E84.11 Meconium ileus in cystic fibrosis
- E84.19 Cystic fibrosis with other intestinal manifestations
- E84.8 Cystic fibrosis with other manifestations
- E84.9 Cystic fibrosis, unspecified
Cystic fibrosis (E84)
Instructional Notations
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- mucoviscidosis
Code Also
A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.
- exocrine pancreatic insufficiency K86.81
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Calgranulin A
A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.
Cystic Fibrosis
An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Cystic Fibrosis Transmembrane Conductance Regulator
A chloride channel that regulates secretion in many exocrine tissues. Abnormalities in the CFTR gene have been shown to cause cystic fibrosis. (Hum Genet 1994;93(4):364-8)
Meconium Ileus
Intestinal obstruction caused by congealed MECONIUM in the distal ILEUM and CECUM. It presents shortly after birth as a failure to pass meconium and frequently occurs in infants with CYSTIC FIBROSIS.
