ICD-10-CM Code E88.1

Lipodystrophy, not elsewhere classified

Version 2021 Billable Code

Valid for Submission

E88.1 is a billable code used to specify a medical diagnosis of lipodystrophy, not elsewhere classified. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code E88.1 might also be used to specify conditions or terms like acquired generalized lipodystrophy, acquired partial lipodystrophy, acquired partial lipodystrophy, congenital anomaly of subcutaneous tissue, congenital anomaly of subcutaneous tissue, congenital generalized lipodystrophy, etc

Short Description:Lipodystrophy, not elsewhere classified
Long Description:Lipodystrophy, not elsewhere classified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E88.1:

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Lipodystrophy NOS

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E88.1 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired generalized lipodystrophy
  • Acquired partial lipodystrophy
  • Acquired partial lipodystrophy
  • Congenital anomaly of subcutaneous tissue
  • Congenital anomaly of subcutaneous tissue
  • Congenital generalized lipodystrophy
  • Diabetes mellitus due to genetic defect in insulin action
  • Familial partial lipodystrophy
  • Familial partial lipodystrophy Dunnigan type
  • Familial partial lipodystrophy Kobberling type
  • Genetic lipodystrophy
  • Genetic lipodystrophy
  • Genetic lipodystrophy
  • Glucose-galactose malabsorption
  • Insulin adverse reaction
  • Insulin lipoatrophy
  • Insulin resistance
  • Lipoatrophic diabetes
  • Lipoatrophy
  • Lipoatrophy and lipodystrophy
  • Lipoatrophy caused by antiretroviral drug
  • Lipoatrophy due to injected corticosteroid
  • Lipodystrophia centrifugalis abdominalis infantalis
  • Lipodystrophy
  • Lipodystrophy caused by antiretroviral drug
  • Lipodystrophy due to peptidic growth factors deficiency
  • Lipodystrophy of face
  • Lipodystrophy, intellectual disability, deafness syndrome
  • Lipodystrophy, partial, with Rieger anomaly, short stature, and insulinopenic diabetes mellitus
  • Localized idiopathic lipoatrophy
  • Localized lipoatrophy
  • Localized lipoatrophy
  • Localized lipoatrophy
  • Localized lipodystrophy
  • Loss of subcutaneous fat
  • Loss of subcutaneous fat overlying triceps muscle
  • Malabsorption of glucose
  • Marfan's syndrome
  • Membranous lipodystrophy
  • Nakajo-Nishimura syndrome
  • Panniculitis induced localized lipodystrophy
  • Partial face-sparing lipodystrophy
  • Perilipin 1 related familial partial lipodystrophy
  • Post-inflammatory lipoatrophy
  • Progeroid and marfanoid aspect, lipodystrophy syndrome
  • Semicircular lipoatrophy
  • Severe neurodegenerative syndrome with lipodystrophy
  • Widespread lipoatrophy

Convert E88.1 to ICD-9

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Metabolic disorders (E70-E88)
      • Other and unspecified metabolic disorders (E88)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.

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