2024 ICD-10-CM Diagnosis Code E88.819
Insulin resistance, unspecified
- ICD-10-CM Code:
- E88.819
- ICD-10 Code for:
- Insulin resistance, unspecified
- Is Billable?
- Yes - Valid for Submission
- Code Navigator:
E88.819 is a billable diagnosis code used to specify a medical diagnosis of insulin resistance, unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.
Unspecified diagnosis codes like E88.819 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Acanthosis nigricans
- Acanthosis nigricans and insulin resistance with muscle cramp and acral enlargement syndrome
- Bird-headed dwarfism with progressive ataxia, insulin-resistant diabetes, goiter, and primary gonadal insufficiency
- Congenital abnormal shape of metacarpal bone
- Deformity of metacarpal
- Drug resistance to insulin
- Glucose-galactose malabsorption
- Glucose-galactose malabsorption
- Insulin receptor defect
- Insulin resistance
- Insulin resistance
- Longitudinal deficiency of metacarpal bone
- Malabsorption of glucose
- Malabsorption of glucose
- Microcephalic primordial dwarfism, insulin resistance syndrome
- Short fifth metacarpal insulin resistance syndrome
Clinical Information
Insulin Resistance
diminished effectiveness of insulin in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent hyperglycemia or ketosis.Metabolic Syndrome
a cluster of symptoms that are risk factors for cardiovascular diseases and type 2 diabetes mellitus. the major components of metabolic syndrome include abdominal obesity; atherogenic dyslipidemia; hypertension; hyperglycemia; insulin resistance; a proinflammatory state; and a prothrombotic (thrombosis) state.Acanthosis Nigricans
a circumscribed melanosis consisting of a brown-pigmented, velvety verrucosity or fine papillomatosis appearing in the axillae and other body folds. it occurs in association with endocrine disorders, underlying malignancy, administration of certain drugs, or as in inherited disorder.Homeostatic Model Assessment of Insulin Resistance
an assessment of beta-cell function and insulin resistance based on fasting blood glucose and insulin concentrations.Hyperandrogenism, Insulin Resistance, Acanthosis Nigricans Syndrome|HAIR-AN Syndrome
a condition characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans, typically associated with obesity in teenage girls. it is considered to be a subtype of polycystic ovarian syndrome, but may occur in male individuals. etiology is unclear, but some cases may be associated with mutations affecting the tyrosine kinase domain of the insulin receptor.Insulin Receptor Mutation - Associated Insulin Resistance Syndromes
insulin resistance caused by inactivating mutation(s) in the insr gene encoding the insulin receptor.Insulin Resistance
decreased sensitivity to circulating insulin which may result in acanthosis nigicrans, elevated insulin level or hyperglycemia.Insulin Resistance Measurement|INSULINR|Insulin Resistance|Insulin Resistance
the determination of the insulin resistance (cells inability to respond to insulin) in a biological specimen.Insulin Resistance Syndrome
a cluster of closely related metabolic abnormalities associated with insulin resistance that confer an increased risk of the development of type 2 diabetes and cardiovascular disease. these abnormalities may include obesity, high blood pressure, abnormal cholesterol levels, proteinuria, and/or polycystic ovary syndrome.Insulin Resistant Diabetes Mellitus with Acanthosis Nigricans and Hyperandrogenism|Type A Insulin Resistance Syndrome
a syndrome of insulin resistance caused by mutation(s) in the insr gene, encoding the insulin receptor. this condition is characterized by a clinical triad of hyperinsulinemia, acanthosis nigricans, and hyperandrogenism without lipodystrophy. this is the least severe of a spectrum of disorders; the other two conditions are rabson-mendenhall syndrome and donohoe syndrome.Obesity-Associated Insulin Resistance
insulin resistance associated with obesity, which may be attributed in part to impaired insulin signaling in target tissues, or impaired insulin-stimulated glucose transport due to reduced expression of the glucose transporter protein 4.Acanthosis Nigricans
a melanotic cutaneous lesion that develops in the axilla and other body folds. it may be idiopathic, drug-induced, or it may be associated with the presence of an endocrine disorder or malignancy.
New 2024 ICD-10-CM Code
E88.819 is new to ICD-10-CM code set for the FY 2024, effective October 1, 2023. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2023. This is a new and revised code for the FY 2024 (October 1, 2023 - September 30, 2024).
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Resistance, resistant (to)
- - insulin - E88.819
Replacement Code
E88819 replaces the following previously assigned ICD-10-CM code(s):
- E88.81 - Metabolic syndrome
- E88.81 - Metabolic syndrome and other insulin resistance
Code History
- FY 2024 - Code Added, effective from 10/1/2023 through 9/30/2024