2024 ICD-10-CM Diagnosis Code E72.89

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• 2-hydroxyglutaric aciduria
• 3-Phosphoglycerate dehydrogenase deficiency
• 3-phosphoglycerate dehydrogenase deficiency infantile form
• 3-phosphoglycerate dehydrogenase deficiency juvenile form
• 5-Oxoprolinase deficiency
• Alaninemia
• Alpha ketoadipic aciduria
• Aminoacidemia
• Aminoaciduria
• Aminoaciduria
• Aminoaciduria
• Camptodactyly of finger
• Camptodactyly taurinuria syndrome
• Combined D-2-hydroxyglutaric aciduria and L-2-hydroxyglutaric aciduria
• Congenital porphyria
• Deficiency of 3-hydroxyisobutyrate dehydrogenase
• Deficiency of 4-hydroxy-2-oxoglutarate aldolase
• Deficiency of A-ase
• Deficiency of acid-aminoacid ligase
• Deficiency of adenosylhomocysteinase
• Deficiency of alanine aminotransferase
• Deficiency of alanine dehydrogenase
• Deficiency of alanine-oxo-acid aminotransferase
• Deficiency of alanine-tRNA ligase
• Deficiency of aminoacylase 1
• Deficiency of aminoacyl-histidine dipeptidase
• Deficiency of aminoacyltransferase
• Deficiency of aminopeptidase
• Deficiency of aminotransferase
• Deficiency of ammonia-lyase
• Deficiency of asparagine-oxo-acid aminotransferase
• Deficiency of aspartate 4-decarboxylase
• Deficiency of aspartate aminotransferase
• Deficiency of aspartate kinase
• Deficiency of betaine-aldehyde dehydrogenase
• Deficiency of betaine-homocysteine methyltransferase
• Deficiency of carboxy-lyase
• Deficiency of carboxypeptidase A
• Deficiency of carboxypeptidase B
• Deficiency of carnosinase
• Deficiency of choline dehydrogenase
• Deficiency of cysteamine dioxygenase
• Deficiency of cysteine aminotransferase
• Deficiency of cysteine carboxypeptidase
• Deficiency of cysteine proteinase
• Deficiency of cysteinyl-glycine dipeptidase
• Deficiency of cystine reductase
• Deficiency of cytosol aminopeptidase
• Deficiency of D-amino-acid oxidase
• Deficiency of D-aspartate oxidase
• Deficiency of glutamate decarboxylase
• Deficiency of glutamate dehydrogenase
• Deficiency of glutamate-ammonia ligase
• Deficiency of glutaminase
• Deficiency of glutamine phenylacetyltransferase
• Deficiency of glutamine-fructose-6-phosphate aminotransferase
• Deficiency of glutamine-pyruvate aminotransferase
• Deficiency of glycine amidinotransferase
• Deficiency of glycine hydroxymethyltransferase
• Deficiency of guanidinoacetate kinase
• Deficiency of guanidinoacetate methyltransferase
• Deficiency of homoserine kinase
• Deficiency of L-amino-acid oxidase
• Deficiency of L-asparagine amidohydrolase
• Deficiency of L-serine ammonia-lyase
• Deficiency of malonate CoA-transferase
• Deficiency of N-methyl-L-amino-acid oxidase
• Deficiency of phosphoserine phosphatase
• Deficiency of proline dipeptidase
• Deficiency of pyrroline-5-carboxylate reductase
• Deficiency of serine carboxypeptidase
• Deficiency of serine-tRNA ligase
• Deficiency of threonine aldolase
• Deficiency of threonine dehydratase
• Deficiency of threonine-tRNA ligase
• Dibasic aminoaciduria
• Dicarboxylic aminoaciduria syndrome
• Disorder of beta alanine, carnosine AND/OR homocarnosine metabolism
• Disorder of beta and omega amino acid metabolism
• Disorder of creatine synthesis
• Disorder of glutamine metabolism
• Disorder of glutamine metabolism
• Disorder of glutamine metabolism
• Disorder of phenylalanine metabolism
• Disorder of proline AND/OR hydroxyproline metabolism
• Disorder of serine metabolism
• Disorder of tetrahydrobiopterin metabolism
• Disorder of the gamma-glutamyl cycle
• Disorder of threonine metabolism
• Erythropoietic protoporphyria
• Erythropoietic protoporphyria due to gain of function of erythroid-specific aminolevulinic acid synthase 2
• Ferrochelatase deficiency
• Gamma-glutamyl transpeptidase deficiency
• Glutamate-cysteine ligase deficiency
• Glutathione synthase deficiency with 5-oxoprolinuria
• Glutathione synthase deficiency without 5-oxoprolinuria
• Glutathione synthetase deficiency
• Glutathionemia
• Glycoprolinuria
• Hereditary camptodactyly
• Homocarnosinase deficiency
• Hyper-beta-alaninemia
• Hyper-beta-carnosinemia
• Hyperdicarboxylicaminoaciduria AND hyperprolinemia
• Hyperhydroxyprolinemia
• Hyperprolinemia
• Iminoacidopathy
• Inborn error of glutathione metabolism
• Inherited aminoaciduria
• Inherited aminoaciduria
• Inherited aminoaciduria
• Lysinuric protein intolerance
• Neonatal epileptic encephalopathy due to glutaminase deficiency
• Phosphoserine aminotransferase deficiency
• Pipecolic acidemia
• Prolinuria
• Spastic ataxia, dysarthria due to glutaminase deficiency
• Succinate-semialdehyde dehydrogenase deficiency

Clinical Information

• Lysinuric Protein Intolerance

  a disorder caused by the inability to digest and use lysine, arginine, and ornithine. lysinuric protein intolerance is caused by mutations in the slc7a7 gene. y+l amino acid transporter 1, the product of the slc7a7 gene, is involved in transporting lysine, arginine, and ornithine between cells in the body.

Replacement Code

E7289 replaces the following previously assigned ICD-10-CM code(s):

• E72.8 - Other specified disorders of amino-acid metabolism

Patient Education

Amino Acid Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Your digestive system breaks the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body. If you have a metabolic disorder, something goes wrong with this process.

One group of these disorders is amino acid metabolism disorders. They include phenylketonuria (PKU) and maple syrup urine disease. Amino acids are "building blocks" that join together to form proteins. If you have one of these disorders, your body may have trouble breaking down certain amino acids. Or there may be a problem getting the amino acids into your cells. These problems cause a buildup of harmful substances in your body. That can lead to serious, sometimes life-threatening, health problems.

These disorders are usually inherited. A baby who is born with one may not have any symptoms right away. Because the disorders can be so serious, early diagnosis and treatment are critical. Newborn babies get screened for many of them, using blood tests.

Treatments may include special diets, medicines, and supplements. Some babies may also need additional treatments if there are complications.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019