Endocrine, nutritional and metabolic diseases (E00–E89)
ICD-10-CM Chapter 4 (E00–E89) covers a wide range of disorders related to the body's hormones, nutrition, and metabolism. These codes are used to identify conditions involving the endocrine system and metabolic imbalances, such as diabetes and thyroid disorders.
This chapter includes diseases that affect how the body produces and regulates hormones, as well as disorders caused by nutritional deficiencies or metabolic dysfunction. Common conditions covered here include different types of diabetes mellitus, thyroid gland issues like hypothyroidism or hyperthyroidism, disorders of calcium metabolism, and other hormone-related imbalances. These codes are essential for documenting diseases that influence growth, energy use, and nutrient processing, helping healthcare providers diagnose, treat, and manage these complex health issues effectively.
- Disorders of thyroid gland (E00-E07)
- Diabetes mellitus (E08-E13)
- Other disorders of glucose regulation and pancreatic interna
- Disorders of other endocrine glands (E20-E35)
- Intraoperative complications of endocrine system (E36)
- Malnutrition (E40-E46)
- Other nutritional deficiencies (E50-E64)
- Overweight, obesity and other hyperalimentation (E65-E68)
- Metabolic disorders (E70-E88)
- Postprocedural endocrine and metabolic complications and dis
Endocrine, nutritional and metabolic diseases (E00–E89)
Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e.E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Excludes1: transitory endocrine and metabolic disorders specific to newborn (P70-P74)Disorders of thyroid gland (E00-E07)
- Congenital iodine-deficiency syndrome (E00)
- Iodine-deficiency related thyroid disorders and allied conditions (E01)
- Subclinical iodine-deficiency hypothyroidism (E02)
- Other hypothyroidism (E03)
- Other nontoxic goiter (E04)
- Thyrotoxicosis [hyperthyroidism] (E05)
- Thyroiditis (E06)
- Other disorders of thyroid (E07)
Diabetes mellitus (E08-E13)
Other disorders of glucose regulation and pancreatic internal secretion (E15-E16)
Disorders of other endocrine glands (E20-E35)
- Hypoparathyroidism (E20)
- Hyperparathyroidism and other disorders of parathyroid gland (E21)
- Hyperfunction of pituitary gland (E22)
- Hypofunction and other disorders of the pituitary gland (E23)
- Cushing's syndrome (E24)
- Adrenogenital disorders (E25)
- Hyperaldosteronism (E26)
- Other disorders of adrenal gland (E27)
- Ovarian dysfunction (E28)
- Testicular dysfunction (E29)
- Disorders of puberty, not elsewhere classified (E30)
- Polyglandular dysfunction (E31)
- Diseases of thymus (E32)
- Other endocrine disorders (E34)
- Disorders of endocrine glands in diseases classified elsewhere (E35)
Intraoperative complications of endocrine system (E36)
- Intraoperative complications of endocrine system (E36)
Malnutrition (E40-E46)
Other nutritional deficiencies (E50-E64)
- Vitamin A deficiency (E50)
- Thiamine deficiency (E51)
- Niacin deficiency [pellagra] (E52)
- Deficiency of other B group vitamins (E53)
- Ascorbic acid deficiency (E54)
- Vitamin D deficiency (E55)
- Other vitamin deficiencies (E56)
- Dietary calcium deficiency (E58)
- Dietary selenium deficiency (E59)
- Dietary zinc deficiency (E60)
- Deficiency of other nutrient elements (E61)
- Other nutritional deficiencies (E63)
- Sequelae of malnutrition and other nutritional deficiencies (E64)
Overweight, obesity and other hyperalimentation (E65-E68)
Metabolic disorders (E70-E88)
- Disorders of aromatic amino-acid metabolism (E70)
- Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism (E71)
- Other disorders of amino-acid metabolism (E72)
- Lactose intolerance (E73)
- Other disorders of carbohydrate metabolism (E74)
- Disorders of sphingolipid metabolism and other lipid storage disorders (E75)
- Disorders of glycosaminoglycan metabolism (E76)
- Disorders of glycoprotein metabolism (E77)
- Disorders of lipoprotein metabolism and other lipidemias (E78)
- Disorders of purine and pyrimidine metabolism (E79)
- Disorders of porphyrin and bilirubin metabolism (E80)
- Disorders of mineral metabolism (E83)
- Cystic fibrosis (E84)
- Amyloidosis (E85)
- Volume depletion (E86)
- Other disorders of fluid, electrolyte and acid-base balance (E87)
- Other and unspecified metabolic disorders (E88)
Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified (E89)
- Postprocedural endocrine and metabolic complications and disorders, not elsewhere classified (E89)