Endocrine, nutritional and metabolic diseases (E00–E89) ICD-10-CM
Chapter 4 of the ICD-10-CM classification spans codes E00–E89 and contains 1,267 diagnosis codes for endocrine, nutritional and metabolic diseases, of which 971 are billable. The chapter is organized into 10 sections listed below, each linking to its code ranges and individual codes.
Chapter Coding Notes
Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e.E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Excludes1: transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Sections in This Chapter 10 ranges · 1,267 codes
The info icon previews the code ranges inside each row and its instructional notations from the official Tabular List.
About Chapter 4
ICD-10-CM Chapter 4 (E00–E89) covers a wide range of disorders related to the body's hormones, nutrition, and metabolism. These codes are used to identify conditions involving the endocrine system and metabolic imbalances, such as diabetes and thyroid disorders.
This chapter includes diseases that affect how the body produces and regulates hormones, as well as disorders caused by nutritional deficiencies or metabolic dysfunction. Common conditions covered here include different types of diabetes mellitus, thyroid gland issues like hypothyroidism or hyperthyroidism, disorders of calcium metabolism, and other hormone-related imbalances. These codes are essential for documenting diseases that influence growth, energy use, and nutrient processing, helping healthcare providers diagnose, treat, and manage these complex health issues effectively.
Questions About This Page
How many codes are in the E00-E89 range?
The E00-E89 range contains 1,267 ICD-10-CM diagnosis codes in FY 2026. 971 of them are billable, and the rest are category headers that organize the chapter.
What conditions does E00-E89 cover?
The range covers endocrine, nutritional and metabolic diseases. The sections listed above break it into groups of related conditions, and each one links to its own page with the full code list.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
