Endocrine, nutritional and metabolic diseases (E00–E89) ICD-10-CM
Chapter 4 of the ICD-10-CM classification spans codes E00–E89 and contains 1,270 diagnosis codes for endocrine, nutritional and metabolic diseases, of which 973 are billable. The chapter is organized into 10 sections listed below, each linking to its code ranges and individual codes.
Chapter Coding Notes
Note: All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e.E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Excludes1: transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Sections in This Chapter 10 ranges · 1,270 codes
The info icon previews the code ranges inside each row and its instructional notations from the official Tabular List.
About Chapter 4
Thyroid and other gland disorders appear here alongside diabetes, nutrition problems, and disorders of metabolism, the body’s way of using nutrients.
The gland-related blocks separate thyroid disorders, diabetes, other problems with glucose regulation or pancreatic internal secretion, and disorders of other glands. The nutrition blocks separate malnutrition, other nutritional deficiencies, and overweight, obesity, or other excess nutrition. Metabolic disorders form another block.
Separate blocks cover endocrine complications during an operation and endocrine or metabolic disorders after a procedure. The listed seventh character distinguishes the right eye, left eye, both eyes, or an unspecified eye.
FY 2027 changes: The FY 2027 ICD-10-CM update, effective October 1, 2026, added 2 codes and deleted 3 codes in this chapter.
Questions About This Page
How many codes are in the E00-E89 range?
The E00-E89 range contains 1,270 ICD-10-CM diagnosis codes in FY 2027. 973 of them are billable, and the rest are category headers that organize the chapter.
What conditions does E00-E89 cover?
The range covers endocrine, nutritional and metabolic diseases. The sections listed above break it into groups of related conditions, and each one links to its own page with the full code list.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
