2024 ICD-10-CM Diagnosis Code E79.89

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• 5-amino-4-imidazole carboxamide ribosiduria
• Adenine phosphoribosyl transferase deficiency type I
• Adenine phosphoribosyl transferase deficiency type II
• Adenylosuccinate lyase deficiency
• APRT deficiency, Japanese type
• Beta-aminoisobutyric aciduria
• Congenital anomaly of macula
• Cytosine diphosphate choline phosphotransferase deficiency
• Deficiency of 3'-nucleotidase
• Deficiency of 5'-nucleotidase
• Deficiency of adenine deaminase
• Deficiency of allantoicase
• Deficiency of allantoinase
• Deficiency of AMP deaminase
• Deficiency of AMP nucleosidase
• Deficiency of AMP pyrophorylase
• Deficiency of aspartate carbamoyltransferase
• Deficiency of beta-ureidopropionase
• Deficiency of cytidine deaminase
• Deficiency of dihydrouracil dehydrogenase
• Deficiency of DNA repair
• Deficiency of glycine formiminotransferase
• Deficiency of GMP synthase
• Deficiency of homologous recombination deoxyribonucleic acid repair
• Deficiency of phosphoribosylaminoimidazole carboxylase
• Deficiency of phosphoribosylaminoimidazolecarboxamide formyltransferase
• Deficiency of phosphoribosylaminoimidazole-succinocarboxamide synthase
• Deficiency of phosphoribosylformylglycinamidine cyclo-ligase
• Deficiency of phosphoribosylformylglycinamidine synthase
• Deficiency of thymidine phosphorylase
• Deficiency of trimetaphosphatase
• Deficiency of uridine phosphorylase
• Deficiency of xanthine oxidase
• Dihydropyrimidinase deficiency
• Dihydropyrimidine dehydrogenase deficiency
• DNA repair
• DNA repair
• Hereditary orotic aciduria
• Hereditary orotic aciduria, type 1
• Hereditary orotic aciduria, type 2
• Hyperuricuria
• Hypouricemia
• Inosine triphosphate pyrophosphohydrolase deficiency
• NUDT15 deficiency
• Orotic aciduria
• Phosphoribosylpyrophosphate synthetase superactivity
• Ribose-phosphate pyrophosphokinase overactivity
• Secondary orotic aciduria
• Uridine monophosphate hydrolase deficiency

Clinical Information

• DNA End-Joining Repair

  the repair of double-strand dna breaks by rejoining the broken ends of dna to each other directly.

• DNA Repair

  the reconstruction of a continuous two-stranded dna molecule without mismatch from a molecule which contained damaged regions. the major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light.

• DNA Repair Enzymes

  enzymes that are involved in the reconstruction of a continuous two-stranded dna molecule without mismatch from a molecule, which contained damaged regions.

• DNA Repair-Deficiency Disorders

  disorders resulting from defective dna repair processes or the associated cellular responses to dna damage.

• O(6)-Methylguanine-DNA Methyltransferase

  an enzyme that transfers methyl groups from o(6)-methylguanine, and other methylated moieties of dna, to a cysteine residue in itself, thus repairing alkylated dna in a single-step reaction. ec 2.1.1.63.

• Rad52 DNA Repair and Recombination Protein

  a dna-binding protein that mediates dna repair of double strand breaks, and homologous recombination.

• Recombinational DNA Repair

  repair of dna damage by exchange of dna between matching sequences, usually between the allelic dna (alleles) of sister chromatids.

• Dihydropyrimidine Dehydrogenase Deficiency

  an autosomal recessive disorder affecting dihydropyrimidine dehydrogenase and causing familial pyrimidinemia. it is characterized by thymine-uraciluria in homozygous deficient patients. even a partial deficiency in the enzyme leaves individuals at risk for developing severe 5-fluorouracil-associated toxicity.

• DNA

  a deoxyribonucleotide polymer that is the primary genetic material of all cells. eukaryotic and prokaryotic organisms normally contain dna in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. dna, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).

• Hereditary Orotic Aciduria

  an extremely rare autosomal recessive inherited disorder caused by mutations in the umps gene. it is characterized by deficiency of the activity of the pyrimidine pathway enzyme uridine 5'-monophosphate (ump) synthase. clinical manifestations include growth retardation, anemia, and increased excretion of orotic acid in the urine.

New 2024 ICD-10-CM Code

E79.89 is new to ICD-10-CM code set for the FY 2024, effective October 1, 2023. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2023. This is a new and revised code for the FY 2024 (October 1, 2023 - September 30, 2024).

Replacement Code

E7989 replaces the following previously assigned ICD-10-CM code(s):

• E79.8 - Other disorders of purine and pyrimidine metabolism

Code History

• FY 2024 - Code Added, effective from 10/1/2023 through 9/30/2024