2027 ICD-10-CM Diagnosis Code E76Disorders of glycosaminoglycan metabolism

ICD-10-CM Codes›E00–E89›E70-E88›E76

ICD-10-CM E76
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E76 is a non-billable ICD-10-CM category code for disorders of glycosaminoglycan metabolism, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E76.01, E76.02, E76.03, and E76.1.

Code Identity

ICD-10-CM Code
E76
Billable Status
No — Non-Billable Category
Code Describes
Disorders of glycosaminoglycan metabolism
Short Description
Disorders of glycosaminoglycan metabolism
Same as the full description in the CMS dataset.
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE76Disorders of glycosaminoglycan metabolism
This CodeE76Disorders of glycosaminoglycan metabolism

Specific Coding for Disorders of glycosaminoglycan metabolismOverview

Non-specific codes like E76 require more characters. Use one of these billable codes instead:

  • E76.0 for Mucopolysaccharidosis, type I

  • Use E76.01 for Hurler's syndrome

  • Use E76.02 for Hurler-Scheie syndrome

  • Use E76.03 for Scheie's syndrome

  • Use E76.1 for Mucopolysaccharidosis, type II

  • E76.2 for Other mucopolysaccharidoses

  • E76.21 for Morquio mucopolysaccharidoses

  • Use E76.22 for Sanfilippo mucopolysaccharidoses

  • Use E76.29 for Other mucopolysaccharidoses

  • Use E76.3 for Mucopolysaccharidosis, unspecified

  • Use E76.8 for Other disorders of glucosaminoglycan metabolism

  • Use E76.9 for Glucosaminoglycan metabolism disorder, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E76: its own notes plus those printed at block E70-E88 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block E70-E88 Metabolic disorders applies to 286 codes
  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block E70-E88 Metabolic disorders applies to 286 codes
  • Ehlers-Danlos syndromes (Q79.6-)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Patient EducationClinical

Carbohydrate Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system (enzymes) break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E76Overview

What is the ICD-10 code for disorders of glycosaminoglycan metabolism?

E76 is the ICD-10-CM category for disorders of glycosaminoglycan metabolism, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E76 (Disorders of glycosaminoglycan metabolism) a billable code?

No. This is a category header that groups the codes for disorders of glycosaminoglycan metabolism, and headers cannot be submitted on claims. Claims for disorders of glycosaminoglycan metabolism need a more specific code from this category, such as E76.01, E76.02, and E76.03.

Can E76 be reported with a code from E34.5?

Not as a rule. The Excludes1 note at block E70-E88, which applies to E76, lists "androgen insensitivity syndrome (E34.5-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).