2024 ICD-10-CM Diagnosis Code E88.2

Lipomatosis, not elsewhere classified

ICD-10-CM Code:
ICD-10 Code for:
Lipomatosis, not elsewhere classified
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    • Metabolic disorders
      • Other and unspecified metabolic disorders

E88.2 is a billable diagnosis code used to specify a medical diagnosis of lipomatosis, not elsewhere classified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adiposis tuberosa simplex
  • Congenital diffuse lipomatosis
  • Congenital infiltrating lipomatosis of face
  • Encephalocraniocutaneous lipomatosis
  • Epidural lipomatosis
  • Familial multiple lipomata
  • Familial multiple lipomatosis
  • Fat hypertrophy
  • Hemihyperplasia with multiple lipomatosis syndrome
  • Hereditary disorder of lymphatic system
  • Lipoma of skin
  • Lipomatosis
  • Lipomatosis circumscripta
  • Lipomatosis dolorosa
  • Lipomatosis of subcutaneous tissue
  • Lipomatosis of subcutaneous tissue
  • Lipomatosis renis
  • Multiple lipomata
  • Multiple symmetrical lipomatosis
  • Nodular circumscribed lipomatosis
  • Perineural lipomatosis
  • Pierpont syndrome
  • PTEN hamartoma tumor syndrome
  • Roch Leri mesosomatous lipomatosis
  • Segmental outgrowth, lipomatosis, arteriovenous malformation, epidermal nevus syndrome
  • Subcutaneous lipoma

Clinical Classification

Clinical Information

  • Adiposis Dolorosa

    a rare disease characterized by multiple tumor-like fatty deposits that press on nerves in various sites causing pain and weakness. often these lipoma-like structures are located on the trunk and limbs but not on the face and hands.
  • Familial Multiple Lipomatosis

    a rare autosomal disorder characterized by numerous encapsulated lipomas on the trunk and extremities. the lipomas are usually not painful but can cause pain when growing. in rare cases, one lipoma can become painful and progress to multiple painful lipomas; it is then referred to as dercum's disease type iii
  • Lipoma

    a benign tumor composed of fat cells (adipocytes). it can be surrounded by a thin layer of connective tissue (encapsulated), or diffuse without the capsule.
  • Lipomatosis

    a disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling lipoma.
  • Lipomatosis, Multiple Symmetrical

    a condition characterized by the growth of unencapsulated masses of adipose tissue symmetrically deposited around the neck, shoulders, or other sites around the body.
  • Adipocytes

    cells in the body that store fats, usually in the form of triglycerides. white adipocytes are the predominant type and found mostly in the abdominal cavity and subcutaneous tissue. brown adipocytes are thermogenic cells that can be found in newborns of some species and hibernating mammals.
  • Adipose Tissue

    specialized connective tissue composed of fat cells (adipocytes). it is the site of stored fats, usually in the form of triglycerides. in mammals, there are two types of adipose tissue, the white fat and the brown fat. their relative distributions vary in different species with most adipose tissue being white.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.

Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Lipomatosis NOS
  • Lipomatosis (Check) dolorosa Dercum

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert E88.2 to ICD-9-CM

  • ICD-9-CM Code: 272.8 - Lipoid metabol dis NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.


[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.