Valid for Submission
E75.26 is a billable diagnosis code used to specify a medical diagnosis of sulfatase deficiency. The code E75.26 is valid during the fiscal year 2022 from October 01, 2021 through September 30, 2022 for the submission of HIPAA-covered transactions.
The ICD-10-CM code E75.26 might also be used to specify conditions or terms like deficiency of sulfatase.
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E75.26:
Inclusion TermsInclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Multiple sulfatase deficiency (MSD)
Index to Diseases and Injuries
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E75.26 are found in the index:
- - MSD (multiple sulfatase deficiency) - E75.26
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Deficiency of sulfatase
- LEUKODYSTROPHY METACHROMATIC-. an autosomal recessive metabolic disease caused by a deficiency of cerebroside sulfatase leading to intralysosomal accumulation of cerebroside sulfate sulfoglycosphingolipids in the nervous system and other organs. pathological features include diffuse demyelination and metachromatically staining granules in many cell types such as the glial cells. there are several allelic and nonallelic forms with a variety of neurological symptoms.
- MUCOPOLYSACCHARIDOSIS III-. mucopolysaccharidosis characterized by heparitin sulfate in the urine progressive mental retardation mild dwarfism and other skeletal disorders. there are four clinically indistinguishable but biochemically distinct forms each due to a deficiency of a different enzyme.
- ICHTHYOSIS X LINKED-. chronic form of ichthyosis that is inherited as a sex linked recessive trait carried on the x chromosome and transmitted to the male offspring. it is characterized by severe scaling especially on the extremities and is associated with steroid sulfatase deficiency.
E7526 replaces the following previously assigned ICD-10 code(s):
Information for Patients
Genetic Brain Disorders
A genetic brain disorder is caused by a variation or a mutation in a gene. A variation is a different form of a gene. A mutation is a change in a gene. Genetic brain disorders affect the development and function of the brain.
Some genetic brain disorders are due to random gene mutations or mutations caused by environmental exposure, such as cigarette smoke. Other disorders are inherited, which means that a mutated gene or group of genes is passed down through a family. They can also be due to a combination of both genetic changes and other outside factors.
Some examples of genetic brain disorders include
- Tay-Sachs disease
- Wilson disease
Many people with genetic brain disorders fail to produce enough of certain proteins that influence brain development and function. These brain disorders can cause serious problems that affect the nervous system. Some have treatments to control symptoms. Some are life-threatening.
[Learn More in MedlinePlus]
Lipid Metabolism Disorders
Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system (enzymes) break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues. If you have a metabolic disorder, something goes wrong with this process.
Lipid metabolism disorders, such as Gaucher disease and Tay-Sachs disease, involve lipids. Lipids are fats or fat-like substances. They include oils, fatty acids, waxes, and cholesterol. If you have one of these disorders, you may not have enough enzymes to break down lipids. Or the enzymes may not work properly and your body can't convert the fats into energy. They cause a harmful amount of lipids to build up in your body. Over time, that can damage your cells and tissues, especially in the brain, peripheral nervous system, liver, spleen, and bone marrow. Many of these disorders can be very serious, or sometimes even fatal.
These disorders are inherited. Newborn babies get screened for some of them, using blood tests. If there is a family history of one of these disorders, parents can get genetic testing to see whether they carry the gene. Other genetic tests can tell whether the fetus has the disorder or carries the gene for the disorder.
Enzyme replacement therapies can help with a few of these disorders. For others, there is no treatment. Medicines, blood transfusions, and other procedures may help with complications.
[Learn More in MedlinePlus]