Medicare Code Edits · FY 2026 MCE v43.0
Manifestation Diagnoses ICD-10-CM
The manifestation diagnoses edit is a check in Medicare’s claim-validation software, the Medicare Code Editor (MCE). It covers the 422 ICD-10-CM diagnosis codes listed below. Each of these codes describes the manifestation of an underlying disease rather than the disease itself, so the underlying condition is sequenced first and the manifestation code follows as a secondary diagnosis. Claims led by one of these codes are flagged.
✓ Built from the official CMS MCE v43.0 datasetEffective Oct 1, 2025 – Sep 30, 2026
422
ICD-10-CM Codes
83
Code Categories
Never
As Principal Diagnosis
ICD-10-CM
Diagnosis Codes in This Edit 422 codes · 83 categories
422 of 422 shown
D63 Anemia in chronic diseases classified elsewhere3 codes
D64 Other anemias1 code
- D64.1 Secondary sideroblastic anemia due to disease
D72 Other disorders of white blood cells1 code
- D72.18 Eosinophilia in diseases classified elsewhere
D75 Other and unspecified diseases of blood and blood-forming organs1 code
- D75.81 Myelofibrosis
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere1 code
- D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
D84 Other immunodeficiencies1 code
- D84.81 Immunodeficiency due to conditions classified elsewhere
E08 Diabetes mellitus due to underlying condition86 codes
- E08.00 Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)
- E08.01 Diabetes mellitus due to underlying condition with hyperosmolarity with coma
- E08.10 Diabetes mellitus due to underlying condition with ketoacidosis without coma
- E08.11 Diabetes mellitus due to underlying condition with ketoacidosis with coma
- E08.21 Diabetes mellitus due to underlying condition with diabetic nephropathy
- E08.22 Diabetes mellitus due to underlying condition with diabetic chronic kidney disease
- E08.29 Diabetes mellitus due to underlying condition with other diabetic kidney complication
- E08.311 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema
- E08.319 Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy without macular edema
- E08.3211 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, right eye
- E08.3212 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, left eye
- E08.3213 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, bilateral
- E08.3219 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, unspecified eye
- E08.3291 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, right eye
- E08.3292 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, left eye
- E08.3293 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, bilateral
- E08.3299 Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, unspecified eye
- E08.3311 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, right eye
- E08.3312 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, left eye
- E08.3313 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, bilateral
- E08.3319 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, unspecified eye
- E08.3391 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy without macular edema, right eye
- E08.3392 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy without macular edema, left eye
- E08.3393 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy without macular edema, bilateral
- E08.3399 Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy without macular edema, unspecified eye
- E08.3411 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy with macular edema, right eye
- E08.3412 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy with macular edema, left eye
- E08.3413 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy with macular edema, bilateral
- E08.3419 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy with macular edema, unspecified eye
- E08.3491 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy without macular edema, right eye
- E08.3492 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy without macular edema, left eye
- E08.3493 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy without macular edema, bilateral
- E08.3499 Diabetes mellitus due to underlying condition with severe nonproliferative diabetic retinopathy without macular edema, unspecified eye
- E08.3511 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema, right eye
- E08.3512 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema, left eye
- E08.3513 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema, bilateral
- E08.3519 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with macular edema, unspecified eye
- E08.3521 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment involving the macula, right eye
- E08.3522 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment involving the macula, left eye
- E08.3523 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment involving the macula, bilateral
- E08.3529 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment involving the macula, unspecified eye
- E08.3531 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, right eye
- E08.3532 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, left eye
- E08.3533 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, bilateral
- E08.3539 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with traction retinal detachment not involving the macula, unspecified eye
- E08.3541 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, right eye
- E08.3542 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, left eye
- E08.3543 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, bilateral
- E08.3549 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy with combined traction retinal detachment and rhegmatogenous retinal detachment, unspecified eye
- E08.3551 Diabetes mellitus due to underlying condition with stable proliferative diabetic retinopathy, right eye
- E08.3552 Diabetes mellitus due to underlying condition with stable proliferative diabetic retinopathy, left eye
- E08.3553 Diabetes mellitus due to underlying condition with stable proliferative diabetic retinopathy, bilateral
- E08.3559 Diabetes mellitus due to underlying condition with stable proliferative diabetic retinopathy, unspecified eye
- E08.3591 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema, right eye
- E08.3592 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema, left eye
- E08.3593 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema, bilateral
- E08.3599 Diabetes mellitus due to underlying condition with proliferative diabetic retinopathy without macular edema, unspecified eye
- E08.36 Diabetes mellitus due to underlying condition with diabetic cataract
- E08.37X1 Diabetes mellitus due to underlying condition with diabetic macular edema, resolved following treatment, right eye
- E08.37X2 Diabetes mellitus due to underlying condition with diabetic macular edema, resolved following treatment, left eye
- E08.37X3 Diabetes mellitus due to underlying condition with diabetic macular edema, resolved following treatment, bilateral
- E08.37X9 Diabetes mellitus due to underlying condition with diabetic macular edema, resolved following treatment, unspecified eye
- E08.39 Diabetes mellitus due to underlying condition with other diabetic ophthalmic complication
- E08.40 Diabetes mellitus due to underlying condition with diabetic neuropathy, unspecified
- E08.41 Diabetes mellitus due to underlying condition with diabetic mononeuropathy
- E08.42 Diabetes mellitus due to underlying condition with diabetic polyneuropathy
- E08.43 Diabetes mellitus due to underlying condition with diabetic autonomic (poly)neuropathy
- E08.44 Diabetes mellitus due to underlying condition with diabetic amyotrophy
- E08.49 Diabetes mellitus due to underlying condition with other diabetic neurological complication
- E08.51 Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy without gangrene
- E08.52 Diabetes mellitus due to underlying condition with diabetic peripheral angiopathy with gangrene
- E08.59 Diabetes mellitus due to underlying condition with other circulatory complications
- E08.610 Diabetes mellitus due to underlying condition with diabetic neuropathic arthropathy
- E08.618 Diabetes mellitus due to underlying condition with other diabetic arthropathy
- E08.620 Diabetes mellitus due to underlying condition with diabetic dermatitis
- E08.621 Diabetes mellitus due to underlying condition with foot ulcer
- E08.622 Diabetes mellitus due to underlying condition with other skin ulcer
- E08.628 Diabetes mellitus due to underlying condition with other skin complications
- E08.630 Diabetes mellitus due to underlying condition with periodontal disease
- E08.638 Diabetes mellitus due to underlying condition with other oral complications
- E08.641 Diabetes mellitus due to underlying condition with hypoglycemia with coma
- E08.649 Diabetes mellitus due to underlying condition with hypoglycemia without coma
- E08.65 Diabetes mellitus due to underlying condition with hyperglycemia
- E08.69 Diabetes mellitus due to underlying condition with other specified complication
- E08.8 Diabetes mellitus due to underlying condition with unspecified complications
- E08.9 Diabetes mellitus due to underlying condition without complications
E20 Hypoparathyroidism1 code
- E20.811 Secondary hypoparathyroidism in diseases classified elsewhere
E35 Disorders of endocrine glands in diseases classified elsewhere1 code
- E35 Disorders of endocrine glands in diseases classified elsewhere
F02 Dementia in other diseases classified elsewhere24 codes
- F02.80 Dementia in other diseases classified elsewhere, unspecified severity, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
- F02.811 Dementia in other diseases classified elsewhere, unspecified severity, with agitation
- F02.818 Dementia in other diseases classified elsewhere, unspecified severity, with other behavioral disturbance
- F02.82 Dementia in other diseases classified elsewhere, unspecified severity, with psychotic disturbance
- F02.83 Dementia in other diseases classified elsewhere, unspecified severity, with mood disturbance
- F02.84 Dementia in other diseases classified elsewhere, unspecified severity, with anxiety
- F02.A0 Dementia in other diseases classified elsewhere, mild, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
- F02.A11 Dementia in other diseases classified elsewhere, mild, with agitation
- F02.A18 Dementia in other diseases classified elsewhere, mild, with other behavioral disturbance
- F02.A2 Dementia in other diseases classified elsewhere, mild, with psychotic disturbance
- F02.A3 Dementia in other diseases classified elsewhere, mild, with mood disturbance
- F02.A4 Dementia in other diseases classified elsewhere, mild, with anxiety
- F02.B0 Dementia in other diseases classified elsewhere, moderate, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
- F02.B11 Dementia in other diseases classified elsewhere, moderate, with agitation
- F02.B18 Dementia in other diseases classified elsewhere, moderate, with other behavioral disturbance
- F02.B2 Dementia in other diseases classified elsewhere, moderate, with psychotic disturbance
- F02.B3 Dementia in other diseases classified elsewhere, moderate, with mood disturbance
- F02.B4 Dementia in other diseases classified elsewhere, moderate, with anxiety
- F02.C0 Dementia in other diseases classified elsewhere, severe, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxiety
- F02.C11 Dementia in other diseases classified elsewhere, severe, with agitation
- F02.C18 Dementia in other diseases classified elsewhere, severe, with other behavioral disturbance
- F02.C2 Dementia in other diseases classified elsewhere, severe, with psychotic disturbance
- F02.C3 Dementia in other diseases classified elsewhere, severe, with mood disturbance
- F02.C4 Dementia in other diseases classified elsewhere, severe, with anxiety
F54 Psychological and behavioral factors associated with disorders or diseases classified elsewhere1 code
- F54 Psychological and behavioral factors associated with disorders or diseases classified elsewhere
G01 Meningitis in bacterial diseases classified elsewhere1 code
- G01 Meningitis in bacterial diseases classified elsewhere
G02 Meningitis in other infectious and parasitic diseases classified elsewhere1 code
- G02 Meningitis in other infectious and parasitic diseases classified elsewhere
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere2 codes
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere1 code
- G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere4 codes
- G13.0 Paraneoplastic neuromyopathy and neuropathy
- G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease
- G13.2 Systemic atrophy primarily affecting the central nervous system in myxedema
- G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere
G26 Extrapyramidal and movement disorders in diseases classified elsewhere1 code
- G26 Extrapyramidal and movement disorders in diseases classified elsewhere
G32 Other degenerative disorders of nervous system in diseases classified elsewhere3 codes
G47 Sleep disorders6 codes
- G47.27 Circadian rhythm sleep disorder in conditions classified elsewhere
- G47.36 Sleep related hypoventilation in conditions classified elsewhere
- G47.37 Central sleep apnea in conditions classified elsewhere
- G47.421 Narcolepsy in conditions classified elsewhere with cataplexy
- G47.429 Narcolepsy in conditions classified elsewhere without cataplexy
- G47.54 Parasomnia in conditions classified elsewhere
G53 Cranial nerve disorders in diseases classified elsewhere1 code
- G53 Cranial nerve disorders in diseases classified elsewhere
G55 Nerve root and plexus compressions in diseases classified elsewhere1 code
- G55 Nerve root and plexus compressions in diseases classified elsewhere
G59 Mononeuropathy in diseases classified elsewhere1 code
- G59 Mononeuropathy in diseases classified elsewhere
G63 Polyneuropathy in diseases classified elsewhere1 code
- G63 Polyneuropathy in diseases classified elsewhere
G70 Myasthenia gravis and other myoneural disorders1 code
- G70.81 Lambert-Eaton syndrome in disease classified elsewhere
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere3 codes
G91 Hydrocephalus1 code
- G91.4 Hydrocephalus in diseases classified elsewhere
G94 Other disorders of brain in diseases classified elsewhere1 code
- G94 Other disorders of brain in diseases classified elsewhere
G99 Other disorders of nervous system in diseases classified elsewhere3 codes
H22 Disorders of iris and ciliary body in diseases classified elsewhere1 code
- H22 Disorders of iris and ciliary body in diseases classified elsewhere
H28 Cataract in diseases classified elsewhere1 code
- H28 Cataract in diseases classified elsewhere
H32 Chorioretinal disorders in diseases classified elsewhere1 code
- H32 Chorioretinal disorders in diseases classified elsewhere
H36 Retinal disorders in diseases classified elsewhere1 code
- H36.89 Other retinal disorders in diseases classified elsewhere
H42 Glaucoma in diseases classified elsewhere1 code
- H42 Glaucoma in diseases classified elsewhere
H62 Disorders of external ear in diseases classified elsewhere8 codes
- H62.40 Otitis externa in other diseases classified elsewhere, unspecified ear
- H62.41 Otitis externa in other diseases classified elsewhere, right ear
- H62.42 Otitis externa in other diseases classified elsewhere, left ear
- H62.43 Otitis externa in other diseases classified elsewhere, bilateral
- H62.8X1 Other disorders of right external ear in diseases classified elsewhere
- H62.8X2 Other disorders of left external ear in diseases classified elsewhere
- H62.8X3 Other disorders of external ear in diseases classified elsewhere, bilateral
- H62.8X9 Other disorders of external ear in diseases classified elsewhere, unspecified ear
H67 Otitis media in diseases classified elsewhere4 codes
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere8 codes
- H75.00 Mastoiditis in infectious and parasitic diseases classified elsewhere, unspecified ear
- H75.01 Mastoiditis in infectious and parasitic diseases classified elsewhere, right ear
- H75.02 Mastoiditis in infectious and parasitic diseases classified elsewhere, left ear
- H75.03 Mastoiditis in infectious and parasitic diseases classified elsewhere, bilateral
- H75.80 Other specified disorders of middle ear and mastoid in diseases classified elsewhere, unspecified ear
- H75.81 Other specified disorders of right middle ear and mastoid in diseases classified elsewhere
- H75.82 Other specified disorders of left middle ear and mastoid in diseases classified elsewhere
- H75.83 Other specified disorders of middle ear and mastoid in diseases classified elsewhere, bilateral
H82 Vertiginous syndromes in diseases classified elsewhere4 codes
H94 Other disorders of ear in diseases classified elsewhere8 codes
- H94.00 Acoustic neuritis in infectious and parasitic diseases classified elsewhere, unspecified ear
- H94.01 Acoustic neuritis in infectious and parasitic diseases classified elsewhere, right ear
- H94.02 Acoustic neuritis in infectious and parasitic diseases classified elsewhere, left ear
- H94.03 Acoustic neuritis in infectious and parasitic diseases classified elsewhere, bilateral
- H94.80 Other specified disorders of ear in diseases classified elsewhere, unspecified ear
- H94.81 Other specified disorders of right ear in diseases classified elsewhere
- H94.82 Other specified disorders of left ear in diseases classified elsewhere
- H94.83 Other specified disorders of ear in diseases classified elsewhere, bilateral
I31 Other diseases of pericardium1 code
- I31.31 Malignant pericardial effusion in diseases classified elsewhere
I32 Pericarditis in diseases classified elsewhere1 code
- I32 Pericarditis in diseases classified elsewhere
I39 Endocarditis and heart valve disorders in diseases classified elsewhere1 code
- I39 Endocarditis and heart valve disorders in diseases classified elsewhere
I41 Myocarditis in diseases classified elsewhere1 code
- I41 Myocarditis in diseases classified elsewhere
I43 Cardiomyopathy in diseases classified elsewhere1 code
- I43 Cardiomyopathy in diseases classified elsewhere
I52 Other heart disorders in diseases classified elsewhere1 code
- I52 Other heart disorders in diseases classified elsewhere
I68 Cerebrovascular disorders in diseases classified elsewhere3 codes
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere3 codes
J17 Pneumonia in diseases classified elsewhere1 code
- J17 Pneumonia in diseases classified elsewhere
J84 Other interstitial pulmonary diseases3 codes
J91 Pleural effusion in conditions classified elsewhere2 codes
J99 Respiratory disorders in diseases classified elsewhere1 code
- J99 Respiratory disorders in diseases classified elsewhere
K23 Disorders of esophagus in diseases classified elsewhere1 code
- K23 Disorders of esophagus in diseases classified elsewhere
K67 Disorders of peritoneum in infectious diseases classified elsewhere1 code
- K67 Disorders of peritoneum in infectious diseases classified elsewhere
K77 Liver disorders in diseases classified elsewhere1 code
- K77 Liver disorders in diseases classified elsewhere
K82 Other diseases of gallbladder2 codes
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere1 code
- K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
L14 Bullous disorders in diseases classified elsewhere1 code
- L14 Bullous disorders in diseases classified elsewhere
L45 Papulosquamous disorders in diseases classified elsewhere1 code
- L45 Papulosquamous disorders in diseases classified elsewhere
L54 Erythema in diseases classified elsewhere1 code
- L54 Erythema in diseases classified elsewhere
L62 Nail disorders in diseases classified elsewhere1 code
- L62 Nail disorders in diseases classified elsewhere
L86 Keratoderma in diseases classified elsewhere1 code
- L86 Keratoderma in diseases classified elsewhere
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere1 code
- L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere24 codes
- M01.X0 Direct infection of unspecified joint in infectious and parasitic diseases classified elsewhere
- M01.X11 Direct infection of right shoulder in infectious and parasitic diseases classified elsewhere
- M01.X12 Direct infection of left shoulder in infectious and parasitic diseases classified elsewhere
- M01.X19 Direct infection of unspecified shoulder in infectious and parasitic diseases classified elsewhere
- M01.X21 Direct infection of right elbow in infectious and parasitic diseases classified elsewhere
- M01.X22 Direct infection of left elbow in infectious and parasitic diseases classified elsewhere
- M01.X29 Direct infection of unspecified elbow in infectious and parasitic diseases classified elsewhere
- M01.X31 Direct infection of right wrist in infectious and parasitic diseases classified elsewhere
- M01.X32 Direct infection of left wrist in infectious and parasitic diseases classified elsewhere
- M01.X39 Direct infection of unspecified wrist in infectious and parasitic diseases classified elsewhere
- M01.X41 Direct infection of right hand in infectious and parasitic diseases classified elsewhere
- M01.X42 Direct infection of left hand in infectious and parasitic diseases classified elsewhere
- M01.X49 Direct infection of unspecified hand in infectious and parasitic diseases classified elsewhere
- M01.X51 Direct infection of right hip in infectious and parasitic diseases classified elsewhere
- M01.X52 Direct infection of left hip in infectious and parasitic diseases classified elsewhere
- M01.X59 Direct infection of unspecified hip in infectious and parasitic diseases classified elsewhere
- M01.X61 Direct infection of right knee in infectious and parasitic diseases classified elsewhere
- M01.X62 Direct infection of left knee in infectious and parasitic diseases classified elsewhere
- M01.X69 Direct infection of unspecified knee in infectious and parasitic diseases classified elsewhere
- M01.X71 Direct infection of right ankle and foot in infectious and parasitic diseases classified elsewhere
- M01.X72 Direct infection of left ankle and foot in infectious and parasitic diseases classified elsewhere
- M01.X79 Direct infection of unspecified ankle and foot in infectious and parasitic diseases classified elsewhere
- M01.X8 Direct infection of vertebrae in infectious and parasitic diseases classified elsewhere
- M01.X9 Direct infection of multiple joints in infectious and parasitic diseases classified elsewhere
M02 Postinfective and reactive arthropathies25 codes
- M02.80 Other reactive arthropathies, unspecified site
- M02.811 Other reactive arthropathies, right shoulder
- M02.812 Other reactive arthropathies, left shoulder
- M02.819 Other reactive arthropathies, unspecified shoulder
- M02.821 Other reactive arthropathies, right elbow
- M02.822 Other reactive arthropathies, left elbow
- M02.829 Other reactive arthropathies, unspecified elbow
- M02.831 Other reactive arthropathies, right wrist
- M02.832 Other reactive arthropathies, left wrist
- M02.839 Other reactive arthropathies, unspecified wrist
- M02.841 Other reactive arthropathies, right hand
- M02.842 Other reactive arthropathies, left hand
- M02.849 Other reactive arthropathies, unspecified hand
- M02.851 Other reactive arthropathies, right hip
- M02.852 Other reactive arthropathies, left hip
- M02.859 Other reactive arthropathies, unspecified hip
- M02.861 Other reactive arthropathies, right knee
- M02.862 Other reactive arthropathies, left knee
- M02.869 Other reactive arthropathies, unspecified knee
- M02.871 Other reactive arthropathies, right ankle and foot
- M02.872 Other reactive arthropathies, left ankle and foot
- M02.879 Other reactive arthropathies, unspecified ankle and foot
- M02.88 Other reactive arthropathies, vertebrae
- M02.89 Other reactive arthropathies, multiple sites
- M02.9 Reactive arthropathy, unspecified
M14 Arthropathies in other diseases classified elsewhere24 codes
- M14.80 Arthropathies in other specified diseases classified elsewhere, unspecified site
- M14.811 Arthropathies in other specified diseases classified elsewhere, right shoulder
- M14.812 Arthropathies in other specified diseases classified elsewhere, left shoulder
- M14.819 Arthropathies in other specified diseases classified elsewhere, unspecified shoulder
- M14.821 Arthropathies in other specified diseases classified elsewhere, right elbow
- M14.822 Arthropathies in other specified diseases classified elsewhere, left elbow
- M14.829 Arthropathies in other specified diseases classified elsewhere, unspecified elbow
- M14.831 Arthropathies in other specified diseases classified elsewhere, right wrist
- M14.832 Arthropathies in other specified diseases classified elsewhere, left wrist
- M14.839 Arthropathies in other specified diseases classified elsewhere, unspecified wrist
- M14.841 Arthropathies in other specified diseases classified elsewhere, right hand
- M14.842 Arthropathies in other specified diseases classified elsewhere, left hand
- M14.849 Arthropathies in other specified diseases classified elsewhere, unspecified hand
- M14.851 Arthropathies in other specified diseases classified elsewhere, right hip
- M14.852 Arthropathies in other specified diseases classified elsewhere, left hip
- M14.859 Arthropathies in other specified diseases classified elsewhere, unspecified hip
- M14.861 Arthropathies in other specified diseases classified elsewhere, right knee
- M14.862 Arthropathies in other specified diseases classified elsewhere, left knee
- M14.869 Arthropathies in other specified diseases classified elsewhere, unspecified knee
- M14.871 Arthropathies in other specified diseases classified elsewhere, right ankle and foot
- M14.872 Arthropathies in other specified diseases classified elsewhere, left ankle and foot
- M14.879 Arthropathies in other specified diseases classified elsewhere, unspecified ankle and foot
- M14.88 Arthropathies in other specified diseases classified elsewhere, vertebrae
- M14.89 Arthropathies in other specified diseases classified elsewhere, multiple sites
M36 Systemic disorders of connective tissue in diseases classified elsewhere6 codes
- M36.0 Dermato(poly)myositis in neoplastic disease
- M36.1 Arthropathy in neoplastic disease
- M36.2 Hemophilic arthropathy
- M36.3 Arthropathy in other blood disorders
- M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
- M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
M49 Spondylopathies in diseases classified elsewhere10 codes
- M49.80 Spondylopathy in diseases classified elsewhere, site unspecified
- M49.81 Spondylopathy in diseases classified elsewhere, occipito-atlanto-axial region
- M49.82 Spondylopathy in diseases classified elsewhere, cervical region
- M49.83 Spondylopathy in diseases classified elsewhere, cervicothoracic region
- M49.84 Spondylopathy in diseases classified elsewhere, thoracic region
- M49.85 Spondylopathy in diseases classified elsewhere, thoracolumbar region
- M49.86 Spondylopathy in diseases classified elsewhere, lumbar region
- M49.87 Spondylopathy in diseases classified elsewhere, lumbosacral region
- M49.88 Spondylopathy in diseases classified elsewhere, sacral and sacrococcygeal region
- M49.89 Spondylopathy in diseases classified elsewhere, multiple sites in spine
M63 Disorders of muscle in diseases classified elsewhere24 codes
- M63.80 Disorders of muscle in diseases classified elsewhere, unspecified site
- M63.811 Disorders of muscle in diseases classified elsewhere, right shoulder
- M63.812 Disorders of muscle in diseases classified elsewhere, left shoulder
- M63.819 Disorders of muscle in diseases classified elsewhere, unspecified shoulder
- M63.821 Disorders of muscle in diseases classified elsewhere, right upper arm
- M63.822 Disorders of muscle in diseases classified elsewhere, left upper arm
- M63.829 Disorders of muscle in diseases classified elsewhere, unspecified upper arm
- M63.831 Disorders of muscle in diseases classified elsewhere, right forearm
- M63.832 Disorders of muscle in diseases classified elsewhere, left forearm
- M63.839 Disorders of muscle in diseases classified elsewhere, unspecified forearm
- M63.841 Disorders of muscle in diseases classified elsewhere, right hand
- M63.842 Disorders of muscle in diseases classified elsewhere, left hand
- M63.849 Disorders of muscle in diseases classified elsewhere, unspecified hand
- M63.851 Disorders of muscle in diseases classified elsewhere, right thigh
- M63.852 Disorders of muscle in diseases classified elsewhere, left thigh
- M63.859 Disorders of muscle in diseases classified elsewhere, unspecified thigh
- M63.861 Disorders of muscle in diseases classified elsewhere, right lower leg
- M63.862 Disorders of muscle in diseases classified elsewhere, left lower leg
- M63.869 Disorders of muscle in diseases classified elsewhere, unspecified lower leg
- M63.871 Disorders of muscle in diseases classified elsewhere, right ankle and foot
- M63.872 Disorders of muscle in diseases classified elsewhere, left ankle and foot
- M63.879 Disorders of muscle in diseases classified elsewhere, unspecified ankle and foot
- M63.88 Disorders of muscle in diseases classified elsewhere, other site
- M63.89 Disorders of muscle in diseases classified elsewhere, multiple sites
M90 Osteopathies in diseases classified elsewhere72 codes
- M90.50 Osteonecrosis in diseases classified elsewhere, unspecified site
- M90.511 Osteonecrosis in diseases classified elsewhere, right shoulder
- M90.512 Osteonecrosis in diseases classified elsewhere, left shoulder
- M90.519 Osteonecrosis in diseases classified elsewhere, unspecified shoulder
- M90.521 Osteonecrosis in diseases classified elsewhere, right upper arm
- M90.522 Osteonecrosis in diseases classified elsewhere, left upper arm
- M90.529 Osteonecrosis in diseases classified elsewhere, unspecified upper arm
- M90.531 Osteonecrosis in diseases classified elsewhere, right forearm
- M90.532 Osteonecrosis in diseases classified elsewhere, left forearm
- M90.539 Osteonecrosis in diseases classified elsewhere, unspecified forearm
- M90.541 Osteonecrosis in diseases classified elsewhere, right hand
- M90.542 Osteonecrosis in diseases classified elsewhere, left hand
- M90.549 Osteonecrosis in diseases classified elsewhere, unspecified hand
- M90.551 Osteonecrosis in diseases classified elsewhere, right thigh
- M90.552 Osteonecrosis in diseases classified elsewhere, left thigh
- M90.559 Osteonecrosis in diseases classified elsewhere, unspecified thigh
- M90.561 Osteonecrosis in diseases classified elsewhere, right lower leg
- M90.562 Osteonecrosis in diseases classified elsewhere, left lower leg
- M90.569 Osteonecrosis in diseases classified elsewhere, unspecified lower leg
- M90.571 Osteonecrosis in diseases classified elsewhere, right ankle and foot
- M90.572 Osteonecrosis in diseases classified elsewhere, left ankle and foot
- M90.579 Osteonecrosis in diseases classified elsewhere, unspecified ankle and foot
- M90.58 Osteonecrosis in diseases classified elsewhere, other site
- M90.59 Osteonecrosis in diseases classified elsewhere, multiple sites
- M90.60 Osteitis deformans in neoplastic diseases, unspecified site
- M90.611 Osteitis deformans in neoplastic diseases, right shoulder
- M90.612 Osteitis deformans in neoplastic diseases, left shoulder
- M90.619 Osteitis deformans in neoplastic diseases, unspecified shoulder
- M90.621 Osteitis deformans in neoplastic diseases, right upper arm
- M90.622 Osteitis deformans in neoplastic diseases, left upper arm
- M90.629 Osteitis deformans in neoplastic diseases, unspecified upper arm
- M90.631 Osteitis deformans in neoplastic diseases, right forearm
- M90.632 Osteitis deformans in neoplastic diseases, left forearm
- M90.639 Osteitis deformans in neoplastic diseases, unspecified forearm
- M90.641 Osteitis deformans in neoplastic diseases, right hand
- M90.642 Osteitis deformans in neoplastic diseases, left hand
- M90.649 Osteitis deformans in neoplastic diseases, unspecified hand
- M90.651 Osteitis deformans in neoplastic diseases, right thigh
- M90.652 Osteitis deformans in neoplastic diseases, left thigh
- M90.659 Osteitis deformans in neoplastic diseases, unspecified thigh
- M90.661 Osteitis deformans in neoplastic diseases, right lower leg
- M90.662 Osteitis deformans in neoplastic diseases, left lower leg
- M90.669 Osteitis deformans in neoplastic diseases, unspecified lower leg
- M90.671 Osteitis deformans in neoplastic diseases, right ankle and foot
- M90.672 Osteitis deformans in neoplastic diseases, left ankle and foot
- M90.679 Osteitis deformans in neoplastic diseases, unspecified ankle and foot
- M90.68 Osteitis deformans in neoplastic diseases, other site
- M90.69 Osteitis deformans in neoplastic diseases, multiple sites
- M90.80 Osteopathy in diseases classified elsewhere, unspecified site
- M90.811 Osteopathy in diseases classified elsewhere, right shoulder
- M90.812 Osteopathy in diseases classified elsewhere, left shoulder
- M90.819 Osteopathy in diseases classified elsewhere, unspecified shoulder
- M90.821 Osteopathy in diseases classified elsewhere, right upper arm
- M90.822 Osteopathy in diseases classified elsewhere, left upper arm
- M90.829 Osteopathy in diseases classified elsewhere, unspecified upper arm
- M90.831 Osteopathy in diseases classified elsewhere, right forearm
- M90.832 Osteopathy in diseases classified elsewhere, left forearm
- M90.839 Osteopathy in diseases classified elsewhere, unspecified forearm
- M90.841 Osteopathy in diseases classified elsewhere, right hand
- M90.842 Osteopathy in diseases classified elsewhere, left hand
- M90.849 Osteopathy in diseases classified elsewhere, unspecified hand
- M90.851 Osteopathy in diseases classified elsewhere, right thigh
- M90.852 Osteopathy in diseases classified elsewhere, left thigh
- M90.859 Osteopathy in diseases classified elsewhere, unspecified thigh
- M90.861 Osteopathy in diseases classified elsewhere, right lower leg
- M90.862 Osteopathy in diseases classified elsewhere, left lower leg
- M90.869 Osteopathy in diseases classified elsewhere, unspecified lower leg
- M90.871 Osteopathy in diseases classified elsewhere, right ankle and foot
- M90.872 Osteopathy in diseases classified elsewhere, left ankle and foot
- M90.879 Osteopathy in diseases classified elsewhere, unspecified ankle and foot
- M90.88 Osteopathy in diseases classified elsewhere, other site
- M90.89 Osteopathy in diseases classified elsewhere, multiple sites
N08 Glomerular disorders in diseases classified elsewhere1 code
- N08 Glomerular disorders in diseases classified elsewhere
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere1 code
- N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
N22 Calculus of urinary tract in diseases classified elsewhere1 code
- N22 Calculus of urinary tract in diseases classified elsewhere
N29 Other disorders of kidney and ureter in diseases classified elsewhere1 code
- N29 Other disorders of kidney and ureter in diseases classified elsewhere
N33 Bladder disorders in diseases classified elsewhere1 code
- N33 Bladder disorders in diseases classified elsewhere
N37 Urethral disorders in diseases classified elsewhere1 code
- N37 Urethral disorders in diseases classified elsewhere
N48 Other disorders of penis1 code
- N48.32 Priapism due to disease classified elsewhere
N51 Disorders of male genital organs in diseases classified elsewhere1 code
- N51 Disorders of male genital organs in diseases classified elsewhere
N52 Male erectile dysfunction1 code
- N52.1 Erectile dysfunction due to diseases classified elsewhere
N74 Female pelvic inflammatory disorders in diseases classified elsewhere1 code
- N74 Female pelvic inflammatory disorders in diseases classified elsewhere
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere2 codes
P91 Other disturbances of cerebral status of newborn1 code
- P91.811 Neonatal encephalopathy in diseases classified elsewhere
R47 Speech disturbances, not elsewhere classified1 code
- R47.82 Fluency disorder in conditions classified elsewhere
R50 Fever of other and unknown origin1 code
- R50.81 Fever presenting with conditions classified elsewhere
Z91 Personal risk factors, not elsewhere classified1 code
- Z91.83 Wandering in diseases classified elsewhere
Questions About This Code Edit
What is the manifestation diagnoses Medicare code edit?
Manifestation codes describe the manifestation of an underlying disease, not the disease itself, and therefore should not be used as a principal diagnosis. Claims that fail the check are flagged for correction before payment.
How many ICD-10-CM codes are on the manifestation diagnoses list?
The FY 2026 list contains 422 diagnosis codes across 83 code categories, imported from the CMS Definitions of Medicare Code Edits v43.0.
What happens when a claim triggers this edit?
Each of these codes describes the manifestation of an underlying disease rather than the disease itself, so the underlying condition is sequenced first and the manifestation code follows as a secondary diagnosis. Claims led by one of these codes are flagged.
Does this edit make the codes invalid for billing?
No. Every code on this list is a valid ICD-10-CM code. The edit checks how the code is used on the claim, not whether the code exists.
Other ICD-10-CM Medicare Code Edits
Adult DiagnosesNewborn DiagnosesPediatric DiagnosesMaternity DiagnosesQuestionable AdmissionUnacceptable Principal DiagnosisOutcome of DeliveryUnspecified Codes
Source: CMS Definitions of Medicare Code Edits v43.0, effective October 1, 2025 through September 30, 2026. Code lists are imported directly from the official manual. See also the ICD-10-PCS procedure edits and the MS-DRG list.
