ICD-10-CM Code E85.2

Heredofamilial amyloidosis, unspecified

Version 2021 Billable Code

Valid for Submission

E85.2 is a billable code used to specify a medical diagnosis of heredofamilial amyloidosis, unspecified. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code E85.2 might also be used to specify conditions or terms like abri amyloidosis, adan amyloidosis, agel amyloidosis, amyloid myopathy, amyloid nephropathy, amyloid nephropathy, etc

Short Description:Heredofamilial amyloidosis, unspecified
Long Description:Heredofamilial amyloidosis, unspecified

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E85.2 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • ABri amyloidosis
  • ADan amyloidosis
  • AGel amyloidosis
  • Amyloid myopathy
  • Amyloid nephropathy
  • Amyloid nephropathy
  • Autosomal dominant beta2-microglobulinic amyloidosis
  • Cerebral amyloid angiopathy
  • Cerebral amyloid angiopathy
  • Chronic organic mental disorder
  • Chronic organic mental disorder
  • Cryopyrin associated periodic syndrome
  • Familial amyloid nephropathy with urticaria AND deafness
  • Familial lichen amyloidosis
  • Familial localized cutaneous amyloidosis
  • Familial non-neuropathic amyloidosis
  • Familial visceral amyloidosis, Ostertag type
  • Hereditary amyloidosis
  • Hereditary cerebrovascular amyloidosis
  • Hereditary periodic fever
  • Hereditary systemic amyloidosis
  • Heredofamilial systemic amyloidosis affecting skin
  • Localized hereditary amyloidosis
  • Primary familial amyloid myopathy
  • Primary localized cutaneous amyloidosis
  • Prion protein systemic amyloidosis
  • Systemic amyloidosis affecting skin
  • Systemic amyloidosis affecting skin

Diagnostic Related Groups

The ICD-10 code E85.2 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2021.


Convert E85.2 to ICD-9

  • 277.39 - Amyloidosis NEC (Approximate Flag)

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

There are three main types of amyloidosis:

  • Primary - with no known cause
  • Secondary - caused by another disease, including some types of cancer
  • Familial - passed down through genes

Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.

  • Cardiac amyloidosis (Medical Encyclopedia)
  • Hereditary amyloidosis (Medical Encyclopedia)
  • Primary amyloidosis (Medical Encyclopedia)
  • Secondary systemic amyloidosis (Medical Encyclopedia)

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