2024 ICD-10-CM Diagnosis Code E85.4

Organ-limited amyloidosis

ICD-10-CM Code:
E85.4
ICD-10 Code for:
Organ-limited amyloidosis
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)

E85.4 is a billable diagnosis code used to specify a medical diagnosis of organ-limited amyloidosis. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Acquired abnormality of atrium
  • Age-related amyloidosis
  • Age-related amyloidosis
  • Age-related amyloidosis
  • Amyloid disease of the urethra
  • Amyloid nephropathy
  • Amyloid of bladder
  • Amyloid of cornea
  • Amyloid of prostate
  • Amyloid of testes
  • Amyloid of ureter
  • Amyloid of vitreous
  • Amyloidosis cutis dyschromia
  • Amyloidosis limited to skin
  • Amyloidosis limited to skin
  • Amyloidosis of skin
  • Amyloidosis of small intestine
  • Amyloidosis of spleen
  • Arthritis secondary to amyloidosis
  • Arthritis secondary to amyloidosis
  • Autonomic neuropathy due to amyloidosis
  • Beta-2 microglobulin arthropathy
  • Bullous cutaneous amyloidosis
  • Cardiac familial non-neuropathic amyloidosis
  • Cerebral amyloid angiopathy
  • Conjunctival amyloidosis
  • Danish type familial amyloid cardiomyopathy
  • Deposit on gingivae
  • Dominant primary localized cutaneous amyloidosis
  • Enlargement of tongue
  • Familial amyloid polyneuropathy
  • Familial amyloid polyneuropathy with cutaneous amyloidosis
  • Familial cardiomyopathy
  • Familial non-neuropathic amyloidosis
  • Gingival amyloidosis
  • Glomerular disorder due to amyloidosis
  • Glomerular disorder due to organ-limited amyloidosis
  • Hepatic amyloidosis
  • Hereditary cerebral amyloid angiopathy, Dutch type
  • Hereditary cerebral hemorrhage with amyloidosis
  • Hereditary cerebrovascular amyloidosis
  • Hereditary oculoleptomeningeal amyloid angiopathy
  • Heredofamilial systemic amyloidosis affecting skin
  • Infiltrative cardiomyopathy
  • Isolated atrial amyloid
  • Isolated corneal amyloidosis
  • Laryngeal amyloidosis
  • Lichen amyloidosis
  • Localized amyloidosis
  • Localized hereditary amyloidosis
  • Localized hereditary amyloidosis
  • Localized non-hereditary amyloidosis
  • Localized non-hereditary amyloidosis
  • Macroglossia due to amyloidosis
  • Macular cutaneous amyloidosis
  • Macule of skin
  • Myocardial degeneration
  • Neuropathy associated with dysproteinemias
  • Ocular amyloid deposit
  • Poikilodermal cutaneous amyloid
  • Primary localized cutaneous amyloidosis
  • Primary localized cutaneous amyloidosis
  • Primary localized cutaneous nodular amyloidosis
  • Pulmonary amyloidosis
  • Secondary localized cutaneous amyloidosis
  • Senile brain amyloidosis
  • Senile cardiac amyloidosis
  • Sporadic cerebral amyloid angiopathy
  • Systemic amyloidosis affecting skin

Clinical Classification

Clinical Information

  • Amyloid Neuropathies, Familial

    inherited disorders of the peripheral nervous system associated with the deposition of amyloid in nerve tissue. the different clinical types based on symptoms correspond to the presence of a variety of mutations in several different proteins including transthyretin (prealbumin); apolipoprotein a-i; and gelsolin.
  • Cerebral Amyloid Angiopathy

    a heterogeneous group of sporadic or familial disorders characterized by amyloid deposits in the walls of small and medium sized blood vessels of cerebral cortex and meninges. clinical features include multiple, small lobar cerebral hemorrhage; cerebral ischemia (brain ischemia); and cerebral infarction. cerebral amyloid angiopathy is unrelated to generalized amyloidosis. amyloidogenic peptides in this condition are nearly always the same ones found in alzheimer disease. (from kumar: robbins and cotran: pathologic basis of disease, 7th ed., 2005)
  • Cerebral Amyloid Angiopathy, Familial

    a familial disorder marked by amyloid deposits in the walls of small and medium sized blood vessels of cerebral cortex and meninges.
  • Cerebral Amyloid Angiopathy

    a disorder characterized by the deposition of amyloid in the wall of the vessels in the brain.
  • Cerebral Amyloid Angiopathy, APP-Related|HCHWAD|Hereditary Cerebral Hemorrhage with Amyloidosis-Dutch Type

    an autosomal dominant form of cerebral amyloid angiopathy caused by mutation(s) in the app gene, encoding amyloid-beta a4 protein. the deposition of amyloid in cerebral blood vessels wall may lead to degenerative vascular changes that may result in cerebral hemorrhage. mutation(s) in the app gene may also cause autosomal dominant alzheimer disease 1.
  • Myocardial Degeneration

    degeneration of myocardial tissue.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Localized amyloidosis
  • Transthyretin-related (ATTR) familial amyloid cardiomyopathy

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert E85.4 to ICD-9-CM

  • ICD-9-CM Code: 277.39 - Amyloidosis NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Amyloidosis

Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

There are three main types of amyloidosis:

  • Primary - with no known cause
  • Secondary - caused by another disease, including some types of cancer
  • Familial - passed down through genes

Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.


[Learn More in MedlinePlus]

Amyloidosis & Kidney Disease

Overview of amyloidosis, a condition where abnormal proteins called amyloid build up in organs and tissues, and how the condition affects the kidneys.
[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.