2027 ICD-10-CM Diagnosis Code E79Disorders of purine and pyrimidine metabolism

ICD-10-CM Codes›E00–E89›E70-E88›E79

ICD-10-CM E79
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E79 is a non-billable ICD-10-CM category code for disorders of purine and pyrimidine metabolism, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E79.0, E79.1, E79.2, and E79.81.

Code Identity

ICD-10-CM Code
E79
Billable Status
No — Non-Billable Category
Code Describes
Disorders of purine and pyrimidine metabolism
Short Description
Disorders of purine and pyrimidine metabolism
Same as the full description in the CMS dataset.
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE79Disorders of purine and pyrimidine metabolism
This CodeE79Disorders of purine and pyrimidine metabolism

Specific Coding for Disorders of purine and pyrimidine metabolismOverview

Non-specific codes like E79 require more characters. Use one of these billable codes instead:

  • Use E79.0 for Hyperuricemia without signs of inflammatory arthritis and tophaceous disease

  • Use E79.1 for Lesch-Nyhan syndrome

  • Use E79.2 for Myoadenylate deaminase deficiency

  • E79.8 for Other disorders of purine and pyrimidine metabolism

  • Use E79.81 for Aicardi-Goutieres syndrome

  • Use E79.82 for Hereditary xanthinuria

  • Use E79.89 for Other specified disorders of purine and pyrimidine metabolism

  • Use E79.9 for Disorder of purine and pyrimidine metabolism, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E79: its own notes plus those printed at block E70-E88 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On E79 itself
From Block E70-E88 Metabolic disorders applies to 286 codes
  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block E70-E88 Metabolic disorders applies to 286 codes
  • Ehlers-Danlos syndromes (Q79.6-)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E79, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming E79: they are not reported together with it, unless the two conditions are unrelated.

  • E72 Other disorders of amino-acid metabolism
    purine and pyrimidine metabolism (E79.-)

Excludes2 1

These codes carry an Excludes2 note naming E79: its condition is not part of those codes, and both may be reported when the patient has both.

  • G11.3 Cerebellar ataxia with defective DNA repair
    other disorders of purine and pyrimidine metabolism (E79.-)

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E79Overview

What is the ICD-10 code for disorders of purine and pyrimidine metabolism?

E79 is the ICD-10-CM category for disorders of purine and pyrimidine metabolism, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E79 (Disorders of purine and pyrimidine metabolism) a billable code?

No. This is a category header that groups the codes for disorders of purine and pyrimidine metabolism, and headers cannot be submitted on claims. Claims for disorders of purine and pyrimidine metabolism need a more specific code from this category, such as E79.0, E79.1, and E79.2.

Can E79 be reported with Q87.19?

Not as a rule. The Excludes1 note on E79 lists "Ataxia-telangiectasia (Q87.19)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).