2026 ICD-10-CM Diagnosis Code E72Other disorders of amino-acid metabolism

ICD-10-CM Codes›E00–E89›E70-E88›E72

ICD-10-CM E72
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E72 is a non-billable ICD-10-CM category code for other disorders of amino-acid metabolism, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E72.00, E72.01, E72.02, and E72.03.

Code Identity

ICD-10-CM Code
E72
Billable Status
No — Non-Billable Category
Code Describes
Other disorders of amino-acid metabolism
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE72Other disorders of amino-acid metabolism
This CodeE72Other disorders of amino-acid metabolism

Specific Coding for Other disorders of amino-acid metabolismOverview

Non-specific codes like E72 require more characters. Use one of these billable codes instead:

  • E72.0 for Disorders of amino-acid transport

  • Use E72.00 for Disorders of amino-acid transport, unspecified

  • Use E72.01 for Cystinuria

  • Use E72.02 for Hartnup's disease

  • Use E72.03 for Lowe's syndrome

  • Use E72.04 for Cystinosis

  • Use E72.09 for Other disorders of amino-acid transport

  • E72.1 for Disorders of sulfur-bearing amino-acid metabolism

  • Use E72.10 for Disorders of sulfur-bearing amino-acid metabolism, unspecified

  • Use E72.11 for Homocystinuria

  • Use E72.12 for Methylenetetrahydrofolate reductase deficiency

  • Use E72.19 for Other disorders of sulfur-bearing amino-acid metabolism

  • E72.2 for Disorders of urea cycle metabolism

  • Use E72.20 for Disorder of urea cycle metabolism, unspecified

  • Use E72.21 for Argininemia

  • Use E72.22 for Arginosuccinic aciduria

  • Use E72.23 for Citrullinemia

  • Use E72.29 for Other disorders of urea cycle metabolism

  • Use E72.3 for Disorders of lysine and hydroxylysine metabolism

  • Use E72.4 for Disorders of ornithine metabolism

  • E72.5 for Disorders of glycine metabolism

  • Use E72.50 for Disorder of glycine metabolism, unspecified

  • Use E72.51 for Non-ketotic hyperglycinemia

  • Use E72.52 for Trimethylaminuria

  • E72.53 for Primary hyperoxaluria

  • E72.54 for Secondary hyperoxaluria

  • Use E72.59 for Other disorders of glycine metabolism

  • E72.8 for Other specified disorders of amino-acid metabolism

  • Use E72.81 for Disorders of gamma aminobutyric acid metabolism

  • Use E72.89 for Other specified disorders of amino-acid metabolism

  • Use E72.9 for Disorder of amino-acid metabolism, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

  • disorders of:
  • aromatic amino-acid metabolism E70
  • branched-chain amino-acid metabolism E71.0 E71.2
  • fatty-acid metabolism E71.3
  • purine and pyrimidine metabolism E79
  • gout M1A M10

Patient EducationClinical

Amino Acid Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Your digestive system breaks the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E72Overview

Is E72 (Other disorders of amino-acid metabolism) a billable code?

No. This is a category header that groups the codes for other disorders of amino-acid metabolism, and headers cannot be submitted on claims. Claims for other disorders of amino-acid metabolism need a more specific code from this category, such as E72.00, E72.01, and E72.02.