2022 ICD-10-CM Code E80

Disorders of porphyrin and bilirubin metabolism

Version 2021

Not Valid for Submission

Short Description:Disorders of porphyrin and bilirubin metabolism
Long Description:Disorders of porphyrin and bilirubin metabolism

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Metabolic disorders (E70-E88)
      • Disorders of porphyrin and bilirubin metabolism (E80)

E80 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of disorders of porphyrin and bilirubin metabolism. The code is not specific and is NOT valid for the year 2022 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding for Disorders of porphyrin and bilirubin metabolism

Non-specific codes like E80 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10 codes with a higher level of specificity when coding for disorders of porphyrin and bilirubin metabolism:

  • BILLABLE CODE - Use E80.0 for Hereditary erythropoietic porphyria
  • BILLABLE CODE - Use E80.1 for Porphyria cutanea tarda
  • NON-BILLABLE CODE - E80.2 for Other and unspecified porphyria
  • BILLABLE CODE - Use E80.20 for Unspecified porphyria
  • BILLABLE CODE - Use E80.21 for Acute intermittent (hepatic) porphyria
  • BILLABLE CODE - Use E80.29 for Other porphyria
  • BILLABLE CODE - Use E80.3 for Defects of catalase and peroxidase
  • BILLABLE CODE - Use E80.4 for Gilbert syndrome
  • BILLABLE CODE - Use E80.5 for Crigler-Najjar syndrome
  • BILLABLE CODE - Use E80.6 for Other disorders of bilirubin metabolism
  • BILLABLE CODE - Use E80.7 for Disorder of bilirubin metabolism, unspecified

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E80:


This note appears immediately under a three character code title to further define, or give examples of, the content of the category.

Information for Patients

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.

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Code History

  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)