2026 ICD-10-CM Diagnosis Code E80Disorders of porphyrin and bilirubin metabolism

ICD-10-CM CodesE00–E89E70-E88E80

ICD-10-CM E80
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E80 is a non-billable ICD-10-CM category code for disorders of porphyrin and bilirubin metabolism, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E80.0, E80.1, E80.20, and E80.21.

Code Identity

ICD-10-CM Code
E80
Billable Status
No — Non-Billable Category
Code Describes
Disorders of porphyrin and bilirubin metabolism
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE80Disorders of porphyrin and bilirubin metabolism
This CodeE80Disorders of porphyrin and bilirubin metabolism

Specific Coding for Disorders of porphyrin and bilirubin metabolismOverview

Non-specific codes like E80 require more characters. Use one of these billable codes instead:

  • Use E80.0 for Hereditary erythropoietic porphyria

  • Use E80.1 for Porphyria cutanea tarda

  • E80.2 for Other and unspecified porphyria

  • Use E80.20 for Unspecified porphyria

  • Use E80.21 for Acute intermittent (hepatic) porphyria

  • Use E80.29 for Other porphyria

  • Use E80.3 for Defects of catalase and peroxidase

  • Use E80.4 for Gilbert syndrome

  • Use E80.5 for Crigler-Najjar syndrome

  • Use E80.6 for Other disorders of bilirubin metabolism

  • Use E80.7 for Disorder of bilirubin metabolism, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Includes

  • defects of catalase and peroxidase

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E80Overview

Is E80 (Disorders of porphyrin and bilirubin metabolism) a billable code?

No. This is a category header that groups the codes for disorders of porphyrin and bilirubin metabolism, and headers cannot be submitted on claims. Claims for disorders of porphyrin and bilirubin metabolism need a more specific code from this category, such as E80.0, E80.1, and E80.20.