2026 ICD-10-CM Diagnosis Code E88.10

Approximate Synonyms

The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.

Clinical Information

• HIV-Associated Lipodystrophy Syndrome

  defective metabolism leading to fat maldistribution in patients infected with hiv. the etiology appears to be multifactorial and probably involves some combination of infection-induced alterations in metabolism, direct effects of antiretroviral therapy, and patient-related factors.

• Lipodystrophy

  a collection of heterogenous conditions resulting from defective lipid metabolism and characterized by adipose tissue atrophy. often there is redistribution of body fat resulting in peripheral fat wasting and central adiposity. they include generalized, localized, congenital, and acquired lipodystrophy.

• Lipodystrophy, Congenital Generalized

  congenital disorders, usually autosomal recessive, characterized by severe generalized lack of adipose tissue, extreme insulin resistance, and hypertriglyceridemia.

• Lipodystrophy, Familial Partial

  inherited conditions characterized by the partial loss of adipose tissue, either confined to the extremities with normal or increased fat deposits on the face, neck and trunk (type 1), or confined to the loss of subcutaneous fat from the limbs and trunk (type 2). type 3 is associated with mutation in the gene encoding peroxisome proliferator-activated receptor gamma.

• Lipomatosis, Multiple Symmetrical

  a condition characterized by the growth of unencapsulated masses of adipose tissue symmetrically deposited around the neck, shoulders, or other sites around the body.

• Panniculitis, Peritoneal

  inflammation of the underlying layer of adipose tissue (panniculus) of the peritoneum, usually of the mesentery or the omentum. there are several forms with various names and are usually characterized by infiltration of lymphocytes and neutrophils, fat necrosis, and fibrosis.

• Whipple Disease

  a chronic systemic infection by a gram-positive bacterium, tropheryma whippelii, mainly affecting the small intestine but also the joints; cardiovascular system; and the central nervous system. the disease is characterized by fat deposits in the intestinal mucosa and lymph nodes, malabsorption, diarrhea with fatty stools, malnutrition, and arthritis.

• HIV

  human immunodeficiency virus. a non-taxonomic and historical term referring to any of two species, specifically hiv-1 and/or hiv-2. prior to 1986, this was called human t-lymphotropic virus type iii/lymphadenopathy-associated virus (htlv-iii/lav). from 1986-1990, it was an official species called hiv. since 1991, hiv was no longer considered an official species name; the two species were designated hiv-1 and hiv-2.

• Adipose Tissue

  specialized connective tissue composed of fat cells (adipocytes). it is the site of stored fats, usually in the form of triglycerides. in mammals, there are two types of adipose tissue, the white fat and the brown fat. their relative distributions vary in different species with most adipose tissue being white.

New 2026 ICD-10-CM Code

E88.10 is new to ICD-10-CM code set for the FY 2026, effective October 1, 2025. The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2025. This is a new and revised code for the FY 2026 (October 1, 2025 - September 30, 2026).

Replacement Code

E8810 replaces the following previously assigned ICD-10-CM code(s):

• E88.1 - Lipodystrophy, not elsewhere classified

Code History

• FY 2026 - Code Added, effective from 10/1/2025 through 9/30/2026