ICD-10-CM Code E71.5

Peroxisomal disorders

Version 2021 Non-Billable Code

Not Valid for Submission

E71.5 is a "header" nonspecific and non-billable code code, consider using a code with a higher level of specificity for a diagnosis of peroxisomal disorders. The code is NOT valid for the year 2021 for the submission of HIPAA-covered transactions.

ICD-10:E71.5
Short Description:Peroxisomal disorders
Long Description:Peroxisomal disorders

Consider the following ICD-10 codes with a higher level of specificity:

  • E71.50 - Peroxisomal disorder, unspecified
  • E71.51 - Disorders of peroxisome biogenesis
  • E71.510 - Zellweger syndrome
  • E71.511 - Neonatal adrenoleukodystrophy
  • E71.518 - Other disorders of peroxisome biogenesis
  • E71.52 - X-linked adrenoleukodystrophy
  • E71.520 - Childhood cerebral X-linked adrenoleukodystrophy
  • E71.521 - Adolescent X-linked adrenoleukodystrophy
  • E71.522 - Adrenomyeloneuropathy
  • E71.528 - Other X-linked adrenoleukodystrophy
  • E71.529 - X-linked adrenoleukodystrophy, unspecified type
  • E71.53 - Other group 2 peroxisomal disorders
  • E71.54 - Other peroxisomal disorders
  • E71.540 - Rhizomelic chondrodysplasia punctata
  • E71.541 - Zellweger-like syndrome
  • E71.542 - Other group 3 peroxisomal disorders
  • E71.548 - Other peroxisomal disorders

Tabular List of Diseases and Injuries

The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with guidance for inclusions, exclusions, descriptions and more. The following references are applicable to the code E71.5:

Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Schilder's disease G37.0

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code E71.5 are found in the index:


Clinical Information

  • PEROXISOMAL DISORDERS-. a heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional peroxisomes. peroxisomal enzymatic abnormalities may be single or multiple. biosynthetic peroxisomal pathways are compromised including the ability to synthesize ether lipids and to oxidize long chain fatty acid precursors. diseases in this category include zellweger syndrome; infantile refsum disease; rhizomelic chondrodysplasia chondrodysplasia punctata rhizomelic; hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and adrenoleukodystrophy x linked. neurologic dysfunction is a prominent feature of most peroxisomal disorders.

Code Classification

  • Endocrine, nutritional and metabolic diseases (E00–E90)
    • Metabolic disorders (E70-E88)
      • Disord of branched-chain amino-acid metab & fatty-acid metab (E71)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients


Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.

  • Acidosis (Medical Encyclopedia)
  • Alkalosis (Medical Encyclopedia)
  • Lactic acid test (Medical Encyclopedia)
  • Metabolic acidosis (Medical Encyclopedia)
  • Metabolic neuropathies (Medical Encyclopedia)
  • Pseudohypoparathyroidism (Medical Encyclopedia)

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