2026 ICD-10-CM Diagnosis Code E78Disorders of lipoprotein metabolism and other lipidemias

ICD-10-CM Codes›E00–E89›E70-E88›E78

ICD-10-CM E78
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E78 is a non-billable ICD-10-CM category code for disorders of lipoprotein metabolism and other lipidemias, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E78.00, E78.010, E78.011, and E78.019.

Code Identity

ICD-10-CM Code
E78
Billable Status
No — Non-Billable Category
Code Describes
Disorders of lipoprotein metabolism and other lipidemias
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE78Disorders of lipoprotein metabolism and other lipidemias
This CodeE78Disorders of lipoprotein metabolism and other lipidemias

Specific Coding for Disorders of lipoprotein metabolism and other lipidemiasOverview

Non-specific codes like E78 require more characters. Use one of these billable codes instead:

  • E78.0 for Pure hypercholesterolemia

  • Use E78.00 for Pure hypercholesterolemia, unspecified

  • E78.01 for Familial hypercholesterolemia

  • Use E78.1 for Pure hyperglyceridemia

  • Use E78.2 for Mixed hyperlipidemia

  • Use E78.3 for Hyperchylomicronemia

  • E78.4 for Other hyperlipidemia

  • Use E78.41 for Elevated Lipoprotein(a)

  • Use E78.49 for Other hyperlipidemia

  • Use E78.5 for Hyperlipidemia, unspecified

  • Use E78.6 for Lipoprotein deficiency

  • E78.7 for Disorders of bile acid and cholesterol metabolism

  • Use E78.70 for Disorder of bile acid and cholesterol metabolism, unspecified

  • Use E78.71 for Barth syndrome

  • Use E78.72 for Smith-Lemli-Opitz syndrome

  • Use E78.79 for Other disorders of bile acid and cholesterol metabolism

  • E78.8 for Other disorders of lipoprotein metabolism

  • Use E78.81 for Lipoid dermatoarthritis

  • Use E78.89 for Other lipoprotein metabolism disorders

  • Use E78.9 for Disorder of lipoprotein metabolism, unspecified

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 1 Excludes

Patient EducationClinical

Lipid Metabolism Disorders

Metabolism is the process your body uses to make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system (enzymes) break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E78Overview

Is E78 (Disorders of lipoprotein metabolism and other lipidemias) a billable code?

No. This is a category header that groups the codes for disorders of lipoprotein metabolism and other lipidemias, and headers cannot be submitted on claims. Claims for disorders of lipoprotein metabolism and other lipidemias need a more specific code from this category, such as E78.00, E78.010, and E78.011.