2027 ICD-10-CM Diagnosis Code E84Cystic fibrosis

ICD-10-CM Codes›E00–E89›E70-E88›E84

ICD-10-CM E84
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

E84 is a non-billable ICD-10-CM category code for cystic fibrosis, so it cannot be submitted on claims. Use a more specific code from this category instead, such as E84.0, E84.11, E84.19, and E84.8.

Code Identity

ICD-10-CM Code
E84
Billable Status
No — Non-Billable Category
Code Describes
Cystic fibrosis
Short Description
Cystic fibrosis
Same as the full description in the CMS dataset.
Chapter
E70-E88
Metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE84Cystic fibrosis
This CodeE84Cystic fibrosis

Specific Coding for Cystic fibrosisOverview

Non-specific codes like E84 require more characters. Use one of these billable codes instead:

  • Use E84.0 for Cystic fibrosis with pulmonary manifestations

  • E84.1 for Cystic fibrosis with intestinal manifestations

  • Use E84.11 for Meconium ileus in cystic fibrosis

  • Use E84.19 for Cystic fibrosis with other intestinal manifestations

  • Use E84.8 for Cystic fibrosis with other manifestations

  • Use E84.9 for Cystic fibrosis, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to E84: its own notes plus those printed at block E70-E88 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

  • mucoviscidosis

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block E70-E88 Metabolic disorders applies to 286 codes
  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)
From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block E70-E88 Metabolic disorders applies to 286 codes
  • Ehlers-Danlos syndromes (Q79.6-)

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

  • exocrine pancreatic insufficiency (K86.81)

Notes

General instructions on how these codes are used.

From Chapter 4 (E00-E89) Endocrine, nutritional and metabolic diseases applies to 973 codes
  • All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name E84, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming E84: they are not reported together with it, unless the two conditions are unrelated.

  • Q45.3 Other congenital malformations of pancreas and pancreatic duct
    fibrocystic disease of pancreas (E84.-)

Excludes2 2

These codes carry an Excludes2 note naming E84: its condition is not part of those codes, and both may be reported when the patient has both.

  • Block J40-J4B Chronic lower respiratory diseases
    cystic fibrosis (E84.-)
  • K86 Other diseases of pancreas
    fibrocystic disease of pancreas (E84.-)

Code First 3

These codes say to code first a condition named in the note, and E84 is one of the conditions named.

  • E08 Diabetes mellitus due to underlying condition
    cystic fibrosis (E84.-)
  • J93.12 Secondary spontaneous pneumothorax
    cystic fibrosis (E84.-)
  • Q55.3 Atresia of vas deferens
    any associated cystic fibrosis (E84.-)

Code Also 1

These codes say E84 may also be needed to fully describe the condition. The note gives no sequencing direction.

  • Z71.87 Encounter for pediatric-to-adult transition counseling
    cystic fibrosis (E84.-)

Clinical InformationClinical

  • Cystic Fibrosis

    an autosomal recessive genetic disease of the exocrine glands. it is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator expressed in several organs including the lung, the pancreas, the biliary system, and the sweat glands. cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in airway obstruction; chronic respiratory infections; pancreatic insufficiency; maldigestion; salt depletion; and heat prostration.

Patient EducationClinical

Cystic Fibrosis

Cystic fibrosis (CF) is an inherited disease of the mucus and sweat glands. It affects mostly your lungs, pancreas, liver, intestines, sinuses, and sex organs. CF causes your mucus to be thick and sticky. The mucus clogs the lungs, causing breathing problems and making it easy for bacteria to grow.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About E84Overview

What is the ICD-10 code for cystic fibrosis?

E84 is the ICD-10-CM category for cystic fibrosis, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is E84 (Cystic fibrosis) a billable code?

No. This is a category header that groups the codes for cystic fibrosis, and headers cannot be submitted on claims. Claims for cystic fibrosis need a more specific code from this category, such as E84.0, E84.11, and E84.19.

Can E84 be reported with a code from E34.5?

Not as a rule. The Excludes1 note at block E70-E88, which applies to E84, lists "androgen insensitivity syndrome (E34.5-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).