Disorders of mineral metabolism (E83) ICD-10-CM
The E83 code range covers disorders of mineral metabolism with 40 ICD-10-CM diagnosis codes. 31 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
Codes in the E83 Range 40 codes · 31 billable
- E83 Disorders of mineral metabolismNon-billable
- E83.0 Disorders of copper metabolismNon-billable
- E83.00 Disorder of copper metabolism, unspecified
- E83.01 Wilson's disease
- E83.09 Other disorders of copper metabolism
- E83.1 Disorders of iron metabolismNon-billable
- E83.10 Disorder of iron metabolism, unspecified
- E83.11 HemochromatosisNon-billable
- E83.110 Hereditary hemochromatosis
- E83.111 Hemochromatosis due to repeated red blood cell transfusions
- E83.118 Other hemochromatosis
- E83.119 Hemochromatosis, unspecified
- E83.19 Other disorders of iron metabolism
- E83.2 Disorders of zinc metabolism
- E83.3 Disorders of phosphorus metabolism and phosphatasesNon-billable
- E83.30 Disorder of phosphorus metabolism, unspecified
- E83.31 Familial hypophosphatemia
- E83.32 Hereditary vitamin D-dependent rickets (type 1) (type 2)
- E83.39 Other disorders of phosphorus metabolism
- E83.4 Disorders of magnesium metabolismNon-billable
- E83.40 Disorders of magnesium metabolism, unspecified
- E83.41 Hypermagnesemia
- E83.42 Hypomagnesemia
- E83.49 Other disorders of magnesium metabolism
- E83.5 Disorders of calcium metabolismNon-billable
- E83.50 Unspecified disorder of calcium metabolism
- E83.51 Hypocalcemia
- E83.52 Hypercalcemia
- E83.59 Other disorders of calcium metabolism
- E83.8 Other disorders of mineral metabolismNon-billable
- E83.81 Hungry bone syndrome
- E83.82 Disorders of pyrophosphate metabolismNon-billable
- E83.820 Generalized arterial calcification of infancy with unspecified genetic causality
- E83.821 ENPP1 deficiency causing generalized arterial calcification of infancy
- E83.822 ENPP1 deficiency causing autosomal recessive hypophosphatemic rickets type 2
- E83.823 ABCC6 deficiency causing generalized arterial calcification of infancy
- E83.824 ABCC6 deficiency causing pseudoxanthoma elasticum
- E83.825 CD73 deficiency causing arterial calcification
- E83.89 Other disorders of mineral metabolism
- E83.9 Disorder of mineral metabolism, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the E83 range.
Calcinosis
Pathologic deposition of calcium salts in tissues.
Calciphylaxis
Condition of induced systemic hypersensitivity in which tissues respond to appropriate challenging agents with a sudden local calcification.
Hemochromatosis
A disorder of iron metabolism characterized by a triad of HEMOSIDEROSIS; LIVER CIRRHOSIS; and DIABETES MELLITUS. It is caused by massive iron deposits in parenchymal cells that may develop after a prolonged increase of iron absorption. (Jablonski's Dictionary of Syndromes & Eponymic Diseases, 2d ed)
Hemosiderosis
Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin.
Hepatolenticular Degeneration
A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
Hereditary Hemochromatosis
An inherited metabolic disorder characterized by iron accumulation in the tissues.
Hypercalcemia
Abnormally high level of calcium in the blood.
Hypermagnesemia, CTCAE
A disorder characterized by laboratory test results that indicate an elevation in the concentration of magnesium in the blood.
Hyperphosphatemia
A condition of abnormally high level of PHOSPHATES in the blood, usually significantly above the normal range of 0.84-1.58 mmol per liter of serum.
Hypocalcemia
Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
Hypomagnesemia, CTCAE
A disorder characterized by laboratory test results that indicate a low concentration of magnesium in the blood.
Hypophosphatemia
A condition of an abnormally low level of PHOSPHATES in the blood.
Hypophosphatemia, Familial
An inherited condition of abnormally low serum levels of PHOSPHATES (below 1 mg/liter) which can occur in a number of genetic diseases with defective reabsorption of inorganic phosphorus by the PROXIMAL RENAL TUBULES. This leads to phosphaturia, HYPOPHOSPHATEMIA, and disturbances of cellular and organ functions such as those in X-LINKED HYPOPHOSPHATEMIC RICKETS; OSTEOMALACIA; and FANCONI SYNDROME.
Nephrocalcinosis
A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.
About the E83 Code Range
Mineral metabolism disorders involve how the body handles minerals and related substances. The main subdivisions separate copper, iron, zinc, phosphorus and phosphatases, magnesium, and calcium disorders.
E83.0 includes Wilson's disease. E83.1 includes hemochromatosis, with further distinctions for hereditary cases and cases due to repeated red blood cell transfusions. E83.2 covers zinc disorders, while E83.3 covers phosphorus disorders and phosphatases. Magnesium and calcium subdivisions each distinguish high levels from low levels.
E83.8 groups other mineral metabolism disorders, including pyrophosphate disorders. Those codes distinguish named genetic deficiencies and associated conditions. E83.9 identifies an unspecified mineral metabolism disorder.
Questions About This Page
How many billable codes are in the E83 range?
Of the 40 codes in this range, 31 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the E83 range classify?
The range classifies disorders of mineral metabolism. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
