2026 ICD-10-CM Diagnosis Code E88.9Metabolic disorder, unspecified

ICD-10-CM Codes›E00–E89›E70-E88›E88

ICD-10-CM E88.9
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

E88.9 is a billable ICD-10-CM diagnosis code for metabolic disorder, unspecified. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified and unspecified nutritional and metabolic disorders.

Code Identity

ICD-10-CM Code
E88.9
Billable Status
Yes — Valid for Submission
Code Describes
Metabolic disorder, unspecified
Short Description
Metabolic disorder, unspecified
Same as the full description in the CMS dataset.
Parent Code
E88
Other and unspecified metabolic disorders

Code Classification

ChapterE00–E89Endocrine, nutritional and metabolic diseases
SectionE70-E88Metabolic disorders
CategoryE88Other and unspecified metabolic disorders
This CodeE88.9Metabolic disorder, unspecified

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal metabolic requirement
  • Abnormal metabolic state due to diabetes mellitus
  • Acquired sensorineural hearing loss
  • Acute confusional state, of metabolic origin
  • Acute metabolic disorder
  • Amino acid deficiency
  • Anemia due to metabolic disorder
  • Aplastic anemia associated with metabolic alteration
  • Arthropathy associated with an endocrine AND/OR metabolic disorder
  • Arthropathy due to metabolic disorder
  • Autonomic disorder due to metabolic disorder
  • Autonomic neuropathy due to metabolic disease
  • Benign intracranial hypertension
  • Benign intracranial hypertension due to metabolic disease
  • Bilateral deposit in corneas
  • Cardiac glycogenosis
  • Cardiomyopathy due to mucopolysaccharidosis
  • Cardiomyopathy due to storage disease
  • Carnitine deficiency
  • Carnitine deficiency due to inborn error of metabolism
  • Chorea due to inborn error of metabolism
  • Chorea due to metabolic disorder
  • Chronic metabolic disorder
  • Chronic tubulointerstitial nephritis due to metabolic disease
  • Clinical manifestation of enzyme deficiency
  • Corneal deposit associated with metabolic disorder
  • Corneal deposits due to metabolic disorder
  • Defective biosynthesis
  • Defective metabolism
  • Dementia due to metabolic abnormality
  • Deposit in cornea of bilateral eyes due to metabolic disorder
  • Deposit in cornea of left eye due to metabolic disorder
  • Deposit in cornea of right eye due to metabolic disorder
  • Dilated cardiomyopathy due to metabolic disorder
  • Disorder of neurometabolic regulation
  • Enzymopathy
  • Familial cardiomyopathy
  • Familial restrictive cardiomyopathy
  • Generalized metabolic disorder
  • Glaucoma in endocrine, nutritional and metabolic diseases
  • Hereditary metabolic disease
  • Hypopituitarism due to metabolic disease
  • Inborn error of metabolism
  • Infiltrative cardiomyopathy
  • Inherited metabolic disorder of nervous system
  • Interstitial lung disease due to metabolic disease
  • Intrinsic staining of tooth - metabolic disease
  • Localized metabolic disorder
  • Metabolic and genetic disorder affecting the liver
  • Metabolic and nutritional disorders affecting skin
  • Metabolic bone disease
  • Metabolic complication of procedures
  • Metabolic disease
  • Metabolic disturbance in labor AND/OR delivery
  • Metabolic ileus
  • Metabolic myopathy
  • Metabolic neuropathy
  • Metabolic presbycusis
  • Metabolic renal disease
  • Myelopathy due to metabolic disorder
  • Navajo neurohepatopathy
  • Neonatal metabolic disorder
  • Neuropathy of upper limb due to metabolic disorder
  • Nutritional myopathy
  • Pericarditis due to metabolic disease
  • Peripheral neuropathy due to metabolic disorder
  • Presbycusis
  • Radiculopathy due to metabolic disorder
  • Restrictive cardiomyopathy secondary to familial storage disease
  • Seizures due to metabolic disorder
  • Sinus bradycardia
  • Sinus bradycardia due to metabolic disease
  • Splenomegaly due to storage disease
  • Storage disease
  • Thrombocytopenic purpura associated with metabolic disorder
  • Tremor due to metabolic disorder

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Arthritis, arthritic(acute) (chronic) (nonpyogenic) (subacute)
      • in (due to)
        • metabolic disorder NEC
    • Arthropathy
      • hemophilic NEC
        • in (due to)
          • metabolic disease NOS
    • Arthropathy
      • in (due to)
        • metabolic disease NOS
    • Cardiomyopathy(familial) (idiopathic)
      • metabolic
    • Cataract(cortical) (immature) (incipient)
      • in (due to)
        • metabolic disease
    • Complication(s) (from) (of)
      • metabolic
    • Disease, diseased
      • metabolic, metabolism
    • Disease, diseased
      • skin
        • due to metabolic disorder NEC
    • Disorder(of)
      • metabolism NOS
    • Disorder(of)
      • metabolism NOS
        • congenital
    • Disturbance(s)
      • metabolism
    • Disturbance(s)
      • metabolism
        • general
    • Glaucoma
      • in (due to)
        • metabolic disease NOS
    • Myopathy
      • in (due to)
        • metabolic disease NEC
    • Neuropathy, neuropathic
      • peripheral (nerve)
        • autonomic
          • in (due to)
            • metabolic disease NEC
    • Polyneuropathy(peripheral)
      • in (due to)
        • metabolic disease NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR END016
Other specified and unspecified nutritional and metabolic disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Presbycusis

    gradual bilateral hearing loss associated with aging that is due to progressive degeneration of cochlear structures and central auditory pathways. hearing loss usually begins with the high frequencies then progresses to sounds of middle and low frequencies.

  • Metabolic Myopathy

    a group of rare inherited disorders characterized by a deficiency of enzymes that are involved in metabolic pathways that affect muscles. the disorders are characterized by muscle dysfunction.

  • Presbycusis

    bilateral hearing loss caused by progressive degeneration of cochlear structures and central auditory pathways, typically associated with the aging process.

  • Myocardial Degeneration

    degeneration of myocardial tissue.

Patient EducationClinical

Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert E88.9 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
277.9 Metabolism disorder NOS
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About E88.9Overview

Is E88.9 (Other and unspecified metabolic disorders) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report metabolic disorder, unspecified on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What is the ICD-9 equivalent of E88.9?

Under the General Equivalence Mappings, metabolic disorder, unspecified converts to ICD-9-CM 277.9 (metabolism disorder NOS). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.