Diseases of the musculoskeletal system and connective tissue (M00–M99)
Chapter 13 of the ICD-10-CM, covering codes M00–M99, categorizes diseases affecting the musculoskeletal system and connective tissue. These codes are used to identify disorders involving bones, joints, muscles, ligaments, and related soft tissues, including both inflammatory and non-inflammatory conditions.
This chapter includes a wide range of conditions such as arthritis, osteoporosis, muscular dystrophies, connective tissue diseases like lupus and scleroderma, and various deformities or injuries affecting the musculoskeletal framework. The codes help healthcare providers specify the type and location of musculoskeletal problems for accurate diagnosis, treatment planning, and medical reporting. Medical coders utilize this section to capture the complexity of bone and connective tissue diseases, ranging from acute infections to chronic degenerative disorders. Proper documentation under these codes supports effective communication in patient care and informs clinical decisions related to mobility and structural integrity.
- Infectious arthropathies (M00-M02)
- Autoinflammatory syndromes (M04)
- Inflammatory polyarthropathies (M05-M14)
- Osteoarthritis (M15-M19)
- Other joint disorders (M20-M25)
- Dentofacial anomalies [including malocclusion] and other dis
- Systemic connective tissue disorders (M30-M36)
- Deforming dorsopathies (M40-M43)
- Spondylopathies (M45-M49)
- Other dorsopathies (M50-M54)
- Disorders of muscles (M60-M63)
- Disorders of synovium and tendon (M65-M67)
- Other soft tissue disorders (M70-M79)
- Disorders of bone density and structure (M80-M85)
- Other osteopathies (M86-M90)
- Chondropathies (M91-M94)
- Other disorders of the musculoskeletal system and connective
- Intraoperative and postprocedural complications and disorder
- Periprosthetic fracture around internal prosthetic joint (M9
- Biomechanical lesions, not elsewhere classified (M99)
Diseases of the musculoskeletal system and connective tissue (M00–M99)
Note: Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition
Excludes2: arthropathic psoriasis (L40.5-), certain conditions originating in the perinatal period (P04-P96), certain infectious and parasitic diseases (A00-B99), compartment syndrome (traumatic) (T79.A-), complications of pregnancy, childbirth and the puerperium (O00-O9A), congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99), endocrine, nutritional and metabolic diseases (E00-E88), injury, poisoning and certain other consequences of external causes (S00-T88), neoplasms (C00-D49), symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)Infectious arthropathies (M00-M02)
Autoinflammatory syndromes (M04)
- Autoinflammatory syndromes (M04)
Inflammatory polyarthropathies (M05-M14)
- Rheumatoid arthritis with rheumatoid factor (M05)
- Other rheumatoid arthritis (M06)
- Enteropathic arthropathies (M07)
- Juvenile arthritis (M08)
- Gout (M10)
- Other crystal arthropathies (M11)
- Other and unspecified arthropathy (M12)
- Other arthritis (M13)
- Arthropathies in other diseases classified elsewhere (M14)
- Chronic gout (M1A)
Osteoarthritis (M15-M19)
Other joint disorders (M20-M25)
Dentofacial anomalies [including malocclusion] and other disorders of jaw (M26-M27)
Systemic connective tissue disorders (M30-M36)
- Polyarteritis nodosa and related conditions (M30)
- Other necrotizing vasculopathies (M31)
- Systemic lupus erythematosus (SLE) (M32)
- Dermatopolymyositis (M33)
- Systemic sclerosis [scleroderma] (M34)
- Other systemic involvement of connective tissue (M35)
- Systemic disorders of connective tissue in diseases classified elsewhere (M36)
Deforming dorsopathies (M40-M43)
Spondylopathies (M45-M49)
Other dorsopathies (M50-M54)
Disorders of muscles (M60-M63)
Disorders of synovium and tendon (M65-M67)
Other soft tissue disorders (M70-M79)
Disorders of bone density and structure (M80-M85)
Other osteopathies (M86-M90)
Chondropathies (M91-M94)
Other disorders of the musculoskeletal system and connective tissue (M95)
- Other acquired deformities of musculoskeletal system and connective tissue (M95)
Intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified (M96)
- Intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified (M96)
Periprosthetic fracture around internal prosthetic joint (M97)
- Periprosthetic fracture around internal prosthetic joint (M97)
Biomechanical lesions, not elsewhere classified (M99)
- Biomechanical lesions, not elsewhere classified (M99)